Innovations in Clinical Trials and Research Data Management

Articles published in 2026 in this theme: 15 (scroll down to load remaining articles)

2026

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Optimization of University Counseling Consent Forms With Large Language Models: Multidimensional Comparative Evaluation

Jianchen Luo, Jing Ma, Danni Zhan, Yuhong Zhou, Jiayu Li, Lan Zhang, Wentao Wang

J Med Internet Res 2026 (Apr 01); 28:e86502

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Development and Evaluation of a Human-in-the-Loop Data Curation Training Program to Support a Digital Clinical Trial Platform: Descriptive Feasibility Study

Mirna Issa, Olivia Yang, Jeffrey Doeve, Shreya Arcot, Amanda Chang, Shriya Amara, Shiven Himanshu Bhakta, Iman Baber, Kawan Shali, Qaiss Dweik, Tony Kin Wai Hung

JMIR Form Res 2026 (Mar 25); 10:e81257

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Guide on Selection of Optimal Motivational Themes for Use in a Clinical Trial Recruiting Black US Adults: Survey Study

Tamunotonye Harry, Jingyi Cao, Zaib Hussain, Ruth-Alma N Turkson-Ocran, Stephen P Juraschek, Timothy P Lahey, Timothy B Plante, Yuanyuan Feng

J Med Internet Res 2026 (Mar 19); 28:e75857

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AI-Assisted Systematic Review: Humans Still Need to Review All Abstracts for Inclusion

Hyelin Sung, Deyana Altahsh, Scott Garrison

JMIR Form Res 2026 (Mar 19); 10:e82896

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Personalized Glucose Management With AI: Pilot Study Using a Multiarmed Bandit Approach

Shinji Hotta, Mikko Kytö, Saila Koivusalo, Seppo Heinonen, Pekka Marttinen

JMIR Form Res 2026 (Mar 19); 10:e70826

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Digital Twins for Just-in-Time Adaptive Interventions (JITAIs): Framework for Optimizing and Continually Improving JITAIs

Asim H Gazi, Daiqi Gao, Susobhan Ghosh, Ziping Xu, Anna L Trella, Predrag Klasnja, Susan A Murphy

J Med Internet Res 2026 (Mar 06); 28:e72830

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Preventing and Treating Insomnia Symptoms in Midlife and Older Adults (ASLEEP): Protocol for a Randomized Controlled Trial Using the PROTECT Norge Infrastructure

Jon Arild Aakre, Bjørn Bjorvatn, Martha Therese Gjestsen, Ingvild Dalen, Clive Ballard, Ingelin Testad

JMIR Res Protoc 2026 (Mar 02); 15:e81542

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Digitally Enhanced Routine Outcome Monitoring in Italian Psychotherapy: Protocol for a Longitudinal Implementation Study

Mattia Vincenzo Olive, Antonino La Tona, Vivian Ostwald, Agostino Brugnera, Gianluca Lo Coco, Angelo Compare, Dana Tzur Bitan, Cristina Masella

JMIR Res Protoc 2026 (Mar 02); 15:e82837

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Comparative Evaluation of AmnioGuard and Advanced Platelet-Rich Fibrin When Combined With NovaBone Putty in the Regeneration of Human Periodontal Infrabony Defects: Protocol for a Randomized Controlled Clinical Trial

Geeta Bhandari, Priyanka Jaiswal, Shweta Bhagat, Sakshi Kotecha

JMIR Res Protoc 2026 (Feb 26); 15:e75987

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Impact of Ocular Massage on Intraocular Pressure and Schlemm Canal Dimensions in Healthy Adults: Protocol for a Randomized Controlled Trial

Mingxuan Zhang, Luning Qin, Liangzhang Tan, Yongtao Li, Qing Zhang, Shuhan Wang, Zhihui Zhang, Emmanuel Eric Pazo, Xinjun Ren

JMIR Res Protoc 2026 (Feb 26); 15:e78864

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Evaluation of Reduced Single-Photon Emission Computed Tomography Imaging Protocols and Software Variability in 177Lu-DOTATATE Dosimetry: Protocol for an Exploratory Observational Trial

Takayuki Yagihashi, Kenta Miwa, Noriaki Miyaji, Satoru Sugimoto, Hideki Hayakawa, Noritoshi Kobayashi, Shoko Takano, Taro Murai

JMIR Res Protoc 2026 (Feb 19); 15:e83248

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Real-World Effectiveness and Noninferiority Evaluation and Comparison of Messenger RNA–Based and Protein-Based COVID-19 Vaccines: Protocol for the BEEHIVE Randomized Study With a Hybrid Effectiveness Design

Sarang K Yoon, German L Ellsworth, Steph Battan-Wraith, Andrew L Phillips, Rebecca V Fink, Joshua Griffin, Elizabeth A K Rowley, Jacob McKell, Ashley S Smith, Riley Campbell, Jesse Williams, Sarah W Ball, Hongwei Zhao, Brandy Warren, Matthew D Rousculp, Matthew S Thiese

JMIR Res Protoc 2026 (Jan 27); 15:e80858

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Frameworks for Guiding the Selection of Digital Data Collection Tools Used in Clinical Trials: Protocol for a Systematic Review

Bavatharani Ananthesayanan, Kayode Philip Fadahunsi, Huanhuan Xiong, John O'Donoghue

JMIR Res Protoc 2026 (Jan 22); 15:e78529

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Leveraging AI Large Language Models for Writing Clinical Trial Proposals in Dermatology: Instrument Validation Study

Megan Hauptman, Daniel Copley, Kelly Young, Tran Do, Joseph S Durgin, Albert Yang, Jungsoo Chang, Allison Billi, Mio Nakamura, Trilokraj Tejasvi

JMIR Dermatol 2026 (Jan 12); 9:e76674

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A Real-Life Digital Intervention for Personalized Nutrition in Adults With Overweight or Obesity: Remote Randomized Controlled Trial

Jelle CBC de Jong, Femke PM Hoevenaars, Lotte GP Peters, Charlotte MM Berendsen, Wilrike J Pasman, Martien PM Caspers, Remon Dulos, Suzan Wopereis

J Med Internet Res 2026 (Jan 05); 28:e73367

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