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This paper is in the following e-collection/theme issue:

Letters to the Editor (365) Clinical Information and Decision Making (3444) Natural Language Processing (1206) Artificial Intelligence (4438) Generative Language Models Including ChatGPT (1370)

Published on in Vol 28 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/85726, first published .
Doctor operating MRI scanner, patient inside, medical imaging technology

Human-in-the-Loop as a Safety Guardrail: Clinical Accountability in the Large Language Model Era

Human-in-the-Loop as a Safety Guardrail: Clinical Accountability in the Large Language Model Era

Authors of this article:

Isaac Zablah1 Author Orcid Image ;   Yolly Molina2 Author Orcid Image ;   Antonio Garcia-Loureiro3 Author Orcid Image
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Isaac Zablah   1 * , PhD ;   Yolly Molina   2 * , MSc ;   Antonio Garcia-Loureiro   3 * , PhD

1 Faculty of Medical Sciences, National Autonomous University of Honduras, Tegucigalpa, Honduras

2 Center for Biomedical Imaging Diagnostics Research and Rehabilitation, National Autonomous University of Honduras, Tegucigalpa, Honduras

3 Department of Electronics and Computer Science, Universidade de Santiago de Compostela, Santiago de Compostela, Spain

*all authors contributed equally

Corresponding Author:

  • Isaac Zablah, PhD
  • Faculty of Medical Sciences
  • National Autonomous University of Honduras
  • Calle la Salud SN
  • Tegucigalpa 11101
  • Honduras
  • Email: jose.zablah@unah.edu.hn