Integrated Prediction System for Individualized Ovarian Stimulation and Ovarian Hyperstimulation Syndrome Prevention: Algorithm Development and Validation

Jingjing Chen   ^{1, 2 *} , MD, PhD ;   Jianjuan Zhao   ^{3, 4, 5 *} , MS ;   Huiyu Qiu   ^{1, 2} , MD, MS ;   Yanhui Liu   ⁵ , MD, PhD ;   Yunqi Zhang   ³ , MS ;   Qicheng Sun   ³ , BSc ;   Yan Yi   ^{1, 2} , MD, PhD ;   Hongying Tang   ^{1, 2} , MSN ;   Jing Zhao   ^{1, 2} , MD, PhD ;   Bin Xu   ^{1, 2} , MD, PhD ;   Qiong Zhang   ^{1, 2} , MD, PhD ;   Ge Yang   ⁶ , MD, PhD ;   Hui Li   ^{1, 2} , MD, PhD ;   Junjie Liu   ⁵ , PhD ;   Zhongzhou Yang   ⁷ , PhD ;   Shaolin Liang   ^{3, 4, 5 *} , PhD ;   Yanping Li   ^{1, 2 *} , MD, PhD ;   Jing Fu   ^{1, 2 *} , MD, PhD

¹ Department of Reproductive Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China

² Clinical Research Center for Women’s Reproductive Health in Hunan Province, Changsha, China

³ Digital Health Lab, Institute for Six-sector Economy, Fudan University, Shanghai, China

⁴ Xiangya Hospital, Central South University, Changsha, China

⁵ Reproductive Medicine Department, The Third Affiliated Hospital of Shenzhen University, Shenzhen, China

⁶ Division of Neonatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong, China

⁷ School of Medicine, Sun Yat-sen University, Guangdong, China

*these authors contributed equally