Chatbots and Conversational Agents

Articles published in 2026 in this theme: 65 (scroll down to load remaining articles)

2026

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Artificial Intelligence Discontinuation Effects (AI-DICE): An Emerging Phenomenon in Mental Health Applications

Megan M Kelly, Phoebe S Moore, Adrian H Zai, Jeroan Allison

JMIR AI 2026 (Jun 02); 5:e85419

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Mapping Practice-Based Signals of Generative AI in Psychiatric Care: Qualitative Study of Korean Psychiatrists’ Experiences, Interpretations, and Implementation Priorities

Myungsung Kim, Yoosuk An, Min Jeon, Yunji Lee, Orane Farrah Lahcine, Hyorim Kim, Seonmi Lee, Sangil Lee, Jong-Chul Yang, Sang-Won Jeon, Dooyoung Jung, Chul-Hyun Cho

J Med Internet Res 2026 (Jun 02); 28:e96556

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Use of the Dynamic Systems Development Method to Inform Technology-Assisted Motivational Interviewing (TAMI) for Tobacco Cessation: Qualitative Study

Brian Borsari, Joannalyn Delacruz, Ahson Saiyed, John Layton, Karla D Llanes, Isaac A Mirzadegan, Jing Cheng, Anita S Hargrave-Bouagnon, Meredith C Meacham, Delwyn Catley, Jason Satterfield

JMIR Form Res 2026 (Jun 02); 10:e88125

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Feasibility and Preliminary Effectiveness of the ChulaCancer Mobile Chatbot for Supportive Care of Patients With Breast or Colorectal Cancer Receiving Chemotherapy: Pilot Randomized Controlled Trial

Narawitch Sompornpailin, Thiti Susiriwatananont, Virote Sriuranpong, Suebpong Tanasanvimon, Chanida Vinayanuwattikun, Piyada Sitthideatphaiboon, Nattaya Poovorawan, Nattaya Teeyapun, Nicha Zungsontiporn, Nussara Pakvisal, Poonnakarn Panjasriprakarn, Bussaba Trakarnsanga, Napa Parinyanitikul

JMIR Form Res 2026 (Jun 01); 10:e86149

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Coconstructing CHAMP, an Artificial Intelligence Chatbot for Pediatric Infectious Symptoms Management: Protocol for a Multiphase Participatory Study

Jia Lin, Nikhil Jaiswal, Yuanchao Ma, Bertrand Lebouché, Sebastian Villanueva, Sofiane Achiche, David Lessard, Kim Engler, Simon Berthelot, David Buckeridge, Leo Anthony Celi, Isabelle Gagnon, Jocelyn Gravel, Laurie H Plotnick, Dan Poenaru, Marie-Pascale Pomey, Zoua M Vang, CHAMP Co-Construction Committee, Esli Osmanlliu

JMIR Res Protoc 2026 (May 26); 15:e89852

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Japanese-Language AI Agent System for Human Papillomavirus Vaccine Infoveillance and Public Communication: Development and Feasibility Evaluation

Junyu Liu, Siwen Yang, Dexiu Ma, Qian Niu, Zequn Zhang, Momoko Nagai-Tanima, Tomoki Aoyama

JMIR Infodemiology 2026 (May 21); 6:e90295

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Development, Feasibility, Acceptability, and Usability of an Artificial Intelligence–Powered Chatbot (Suzy) to Support Patients in Substance Use Disorder Recovery: Multiphase Study

Warren Scott Comulada, Dallas Swendeman, Y. Xian Ho, Joanna M Streck, Delta-Marie Lewis, Roxana Rezai, David Warren, Gladys Pachas, Maria Chandler, Jonathan L Jackson, Lillian Gelberg

JMIR Form Res 2026 (May 20); 10:e84683

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Automated Safety Testing and Reporting Application for Conversational Safety Monitoring of Generative AI Tools for Mental Health: Development and Validation Study

Daniel Szoke, Ilana Hutzler, Jerry Liu, Samantha Addante, Zuhaib Akhtar, Dale L Smith, Kirsten Dickins, Charles Small, Sarah Pridgen, Philip Held

JMIR Ment Health 2026 (May 19); 13:e91367

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A Multiassessment and Multiprofessional Agents Approach for Medical Chatbot Risk Estimation: Development and Evaluation Study

Lenard Paulo Velasco Tamayo, Tomohiro Nishiyama, Shaowen Peng, Shoko Wakamiya, Eiji Aramaki

JMIR Med Inform 2026 (May 15); 14:e80416

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Efficacy, User Engagement, and Acceptability of Cognitive Behavioral Therapy–Oriented Psychological Chatbots for Adults With Depressive and/or Anxiety Symptoms: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Bingyan Gong, Nisha Yao, Hangxin Xie, Chuncheng Huang, Tomoko Kishimoto, Howard Berenbaum, Wenting Mu

J Med Internet Res 2026 (May 08); 28:e82677

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Automated Approaches of Text Simplification of Patient Education Materials: Scoping Review

Cornelia Krenn, Christine Loder, Natalie Berger, Klaus Jeitler, Thomas Semlitsch, Andrea Siebenhofer, Denise Wilfling

J Med Internet Res 2026 (May 07); 28:e88365

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Empathy in AI for Health and Care Settings—Definition, Expression, and Measurement: Protocol for a Scoping Review

Alastair Howcroft, Steve Benford, Michel Valstar, Holly Blake

JMIR Res Protoc 2026 (May 05); 15:e93078

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A Bilingual AI-Based Chatbot for Nutrition Education in a Food Is Medicine Intervention for High-Risk Pregnant Women: Design and Development Study

Lorena Macias-Navarro, Nalini Ranjit, Gregory W Bounds, Brendon A Providence, Yesmeena Shmaitelly, Naomi M Tice, Shreela V Sharma

JMIR Form Res 2026 (May 01); 10:e85292

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Current Landscape of Mental Health Conversational Agents From a Trauma-Informed Care Lens: Scoping Review

Faye Kollig, Kira Voelker, Emily Ryan, Rachel Pfafman, Fayika Farhat Nova

JMIR Ment Health 2026 (Apr 30); 13:e77876

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A Fine-Tuned Multimodal AI Chatbot for Dietary Health and Nutrition, Purrfessor: Development and Mixed Methods Evaluation

Linqi Lu, Yifan Deng, Chuan Tian, Sijia Yang, Dhavan V Shah

JMIR AI 2026 (Apr 30); 5:e74111

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A Chatbot to Meet Parents’ Information Needs for Sickle Cell Trait Newborn Screening Results: Multiple Methods Formative Study

Anne C Madeo, Courtney Gauchel, Emerson Borsato, Amy Gaviglio, Kimberly A Kaphingst, Guilherme Del Fiol, Karen Eilbeck

J Med Internet Res 2026 (Apr 30); 28:e86022

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Evaluation of AI Chatbot Responses to a Standardized Patient Query on Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: Cross-Sectional Content Analysis

Meryem Tuba Sönmez, Mehmet Fatih Yetkin, Duygu Arslan Mehdiyev, Nazlı Durmaz Çelik, Merve Bahar Ercan, Pınar Öztürk, Yeşim Eylev Akboğa, Emine Rabia Koç, Semra Mungan

JMIR Med Inform 2026 (Apr 29); 14:e81720

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Building EVA (Educación, Vinculación, y Autoayuda): Tutorial for the Development of a Digital Mental Health Chatbot for Adolescents Living With HIV

Diego Humberto Vasquez, Neil Rupani, Carmen Contreras, Lenka Kolevic, Molly Forrest Franke, Jerome Timothy Galea

J Med Internet Res 2026 (Apr 28); 28:e75351

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Effectiveness of a Fully Automated Mobile Therapeutic Versus a General Chatbot in Reducing Depression and Anxiety and Improving Well-Being: Feasibility Randomized Controlled Trial

Barbora Kuta, Lukas Novak, Radka Zidkova, Jana Furstova, Klara Malinakova, Andrea De Winter, Vít Husek

JMIR Ment Health 2026 (Apr 22); 13:e82642

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Fact-Checking Large Language Model Responses to a Health Care Prompt: Comparative Study

Padhraig Ryan, Orla Davoren, Glyn Elwyn

JMIR Form Res 2026 (Apr 15); 10:e68223

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