Uncovering the Understanding of the Concept of Patient Similarity in Cancer Research and Treatment: Scoping Review

Iryna Manuilova   ¹ , MSc ;   Jan Bossenz   ¹ , BSc ;   Annemarie Bianka Weise   ¹ , BSc ;   Dominik Boehm   ^{2, 3} , MSc ;   Marvin Döbel   ¹ , MSc ;   Silke D Werle   ⁴ , Dr rer nat ;   Arsenij Ustjanzew   ⁵ , MSc ;   Niklas Reimer   ^{6, 7, 8} , MSc ;   Cosima Strantz   ⁹ , MSc ;   Philipp Unberath   ^{2, 10} , Prof Dr ;   Patrick Metzger   ^{11, 12} , Dr rer nat ;   Thomas Pauli   ¹¹ , Dr rer nat ;   Susann Schulze   ¹³ , Dr med ;   Sonja Hiemer   ¹³ , Dr med ;   Irmak Oguztürk   ⁹ ;   Leila Kamkar   ¹⁴ , MSc ;   Hans A Kestler   ⁴ , Prof Dr ;   Hauke Busch   ^{6, 7} , Prof Dr ;   Benedikt Brors   ^{15, 16, 17, 18} , Prof Dr ;   Jan Christoph   ^{1, 19} , Prof Dr

¹ Junior Research Group (Bio-)Medical Data Science, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

² Medical Center for Information and Communication Technology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

³ Bavarian Cancer Research Center (Bayerisches Zentrum für Krebsforschung), Erlangen, Germany

⁴ Institute of Medical Systems Biology, Ulm University, Ulm, Germany

⁵ Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

⁶ Medical Systems Biology Group, Lübeck Institute of Experimental Dermatology, Universität zu Lübeck, Lübeck, Germany

⁷ University Cancer Center Schleswig-Holstein, University Hospital Schleswig-Holstein, Lübeck, Germany

⁸ Medical Data Integration Center, University Hospital Schleswig-Holstein, Lübeck, Germany

⁹ Medical Informatics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

¹⁰ SRH Fürth University of Applied Sciences, Fürth, Germany

¹¹ Institute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

¹² German Cancer Research Center (DKFZ) Heidelberg, Clinical Trial Office, Heidelberg, Germany

¹³ Krukenberg Cancer Center Halle (Saale), Halle (Saale), Germany

¹⁴ Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, Germany

¹⁵ Division Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany

¹⁶ German Cancer Consortium, Heidelberg, Germany

¹⁷ National Center for Tumor Diseases (NCT), Heidelberg, Germany

¹⁸ Medical Faculty Heidelberg and Faculty of Biosciences, Heidelberg University, Heidelberg, Germany

¹⁹ Data Integration Centre of the University Hospital Halle (Saale), Halle (Saale), Germany