Published on in Vol 26 (2024)
Preprints (earlier versions) of this paper are
available at
https://preprints.jmir.org/preprint/50204, first published
.

Journals
- Pavlopoulos A, Rachiotis T, Maglogiannis I. An Overview of Tools and Technologies for Anxiety and Depression Management Using AI. Applied Sciences 2024;14(19):9068 View
- Łukaniszyn M, Majka Ł, Grochowicz B, Mikołajewski D, Kawala-Sterniuk A. Digital Twins Generated by Artificial Intelligence in Personalized Healthcare. Applied Sciences 2024;14(20):9404 View
- Ștefănigă S, Cordoș A, Ivascu T, Feier C, Muntean C, Stupinean C, Călinici T, Aluaș M, Bolboacă S. Advancing Precision Oncology with Digital and Virtual Twins: A Scoping Review. Cancers 2024;16(22):3817 View
- Piras A, Corso R, Benfante V, Ali M, Laudicella R, Alongi P, D'Aviero A, Cusumano D, Boldrini L, Salvaggio G, Di Raimondo D, Tuttolomondo A, Comelli A. Artificial Intelligence and Statistical Models for the Prediction of Radiotherapy Toxicity in Prostate Cancer: A Systematic Review. Applied Sciences 2024;14(23):10947 View
- Mikołajewska E, Masiak J, Mikołajewski D. Applications of Artificial Intelligence-Based Patient Digital Twins in Decision Support in Rehabilitation and Physical Therapy. Electronics 2024;13(24):4994 View
- Penverne Y, Martinez C, Cellier N, Pehlivan C, Jenvrin J, Savary D, Debierre V, Deciron F, Bichri A, Lebastard Q, Montassier E, Leclere B, Fontanili F. A simulation based digital twin approach to assessing the organization of response to emergency calls. npj Digital Medicine 2024;7(1) View
- Petrušić I, Chiang C, Garcia-Azorin D, Ha W, Ornello R, Pellesi L, Rubio-Beltrán E, Ruscheweyh R, Waliszewska-Prosół M, Wells-Gatnik W. Influence of next-generation artificial intelligence on headache research, diagnosis and treatment: the junior editorial board members’ vision – part 2. The Journal of Headache and Pain 2025;26(1) View
- Jones M, Vijayakumar S, Nittala M, Brunson C. An Interdisciplinary Perspective on Improving Cancer Care in the State of Mississippi as an Example of Cancer Care Improvements in the Global South. Cureus 2025 View
- Mirakhori F, Niazi S. Harnessing the AI/ML in Drug and Biological Products Discovery and Development: The Regulatory Perspective. Pharmaceuticals 2025;18(1):47 View
- . AI in Personalized Medicine: Transforming Treatment Plans through Precision Health. Global Journal of Emerging AI and Computing 2025;1(1):34 View
- Haykal D. Digital twins in dermatology: a new era of personalized skin care. Frontiers in Digital Health 2025;7 View
- Shuja N. The Future of Personalized Medicine. DEVELOPMENTAL MEDICO-LIFE-SCIENCES 2024;1(7):1 View
- Amparore D, Piana A, Piramide F, De Cillis S, Checcucci E, Fiori C, Porpiglia F. 3D anatomical digital twins: New generation virtual models to navigate robotic partial nephrectomy. BJUI Compass 2025;6(3) View
- Roopa M, Venugopal K. Digital Twins for Cyber-Physical Healthcare Systems: Architecture, Requirements, Systematic Analysis, and Future Prospects. IEEE Access 2025;13:44963 View
- Vasconez-Gonzalez J, Alexander-León H, Ortiz-Prado E. Digital Health Transformation in Ecuador: Progress, Barriers, and Future Directions. Journal of Medical Systems 2025;49(1) View
- Puniya B. Artificial-intelligence-driven Innovations in Mechanistic Computational Modeling and Digital Twins for Biomedical Applications. Journal of Molecular Biology 2025;437(17):169181 View
- Cui M, He K, Wang F, Paik J. Human Digital Healthcare Engineering for Enhancing the Health and Well-Being of Seafarers and Offshore Workers: A Comprehensive Review. Systems 2025;13(5):335 View
- Alsaedi S, Ogasawara M, Alarawi M, Gao X, Gojobori T. AI-powered precision medicine: utilizing genetic risk factor optimization to revolutionize healthcare. NAR Genomics and Bioinformatics 2025;7(2) View
- Buragohain D, Khichar S, Deng C, Meng Y, Chaudhary S. Analyzing metaverse-based digital therapies, their effectiveness, and potential risks in mental healthcare. Scientific Reports 2025;15(1) View
- Jehel L, Guidère M. Pour une psychiatrie outillée. L'Encéphale 2025;51(6):688 View
- Silva-Aravena F, Morales J, Jayabalan M. e-Health Strategy for Surgical Prioritization: A Methodology Based on Digital Twins and Reinforcement Learning. Bioengineering 2025;12(6):605 View
- Sharon John A, Alagendran S, Sivaprakasam B, Mohan Ramaswamy M, Selvaraj K, Ramanathan S, Velam Chokkalingam P, Ravindran N, Suvaiyarasan S. Impact of artificial intelligence and digital twin technology on cardiovascular disease diagnosis and management challenges and future directions (Review). World Academy of Sciences Journal 2025;7(4):1 View
- Kabir M, Shishir F, Shomaji S, Ray S. Digital twins in healthcare IoT: A systematic review. High-Confidence Computing 2025;5(3):100340 View
- Chaparro-Cárdenas S, Ramirez-Bautista J, Terven J, Córdova-Esparza D, Romero-Gonzalez J, Ramírez-Pedraza A, Chavez-Urbiola E. A Technological Review of Digital Twins and Artificial Intelligence for Personalized and Predictive Healthcare. Healthcare 2025;13(14):1763 View
- Șerban M, Toader C, Covache-Busuioc R. The Collapse of Brain Clearance: Glymphatic-Venous Failure, Aquaporin-4 Breakdown, and AI-Empowered Precision Neurotherapeutics in Intracranial Hypertension. International Journal of Molecular Sciences 2025;26(15):7223 View
- Bhatia M, Kumar R. Exploring digital twin in sustainable development: a scientometric analysis. International Journal of Data Science and Analytics 2025;20(8):6905 View
- Hadar P, Moura L. Clinical Applications of Artificial Intelligence in Neurology Practice. Continuum 2025;31(2):583 View
- Vallée A. Digital Twins for Personalized Medicine Require Epidemiological Data and Mathematical Modeling: Viewpoint. Journal of Medical Internet Research 2025;27:e72411 View
- Lin T, Ming-Fang Yen A, Li-Sheng Chen S, Hsu C, Yeh Y, Hsiu-Hsi Chen T. Artificial intelligence for precision viral surveillance of emerging infectious disease (EID): Data-driven digital twin metaverse-envisioned study. Computers in Biology and Medicine 2025;196:110877 View
- Tubbs A, Vazquez E. Digital twins in increasing diversity in clinical trials: A systematic review. Journal of Biomedical Informatics 2025;169:104879 View
- Șerban M, Toader C, Covache-Busuioc R. The Redox Revolution in Brain Medicine: Targeting Oxidative Stress with AI, Multi-Omics and Mitochondrial Therapies for the Precision Eradication of Neurodegeneration. International Journal of Molecular Sciences 2025;26(15):7498 View
- Saratkar S, Langote M, Kumar P, Gote P, Weerarathna I, Mishra G. Digital twin for personalized medicine development. Frontiers in Digital Health 2025;7 View
- Casado-Suela M, Torres-Macho J, Izquierdo-Martínez A, Ancos-Aracil C, Ferreira-Burguillos L, Madroñal-Cerezo E, Talaván-Zañón T, Castañeda-Mata A, Escobar-Curbelo L, de la Casa-Muñoz A, Ruiz-Navío E, Bustamante-Fermosel A, Franco-Moreno A. A Digital Twin Strategy to Predict Thrombotic Recurrence in Antiphospholipid Syndrome Patients Treated with Direct Oral Anticoagulants vs. Vitamin K Antagonists Using Data from Real-World Populations. Journal of Clinical Medicine 2025;14(16):5716 View
- Vallée A, Feki A, Moawad G, Ayoubi J. A semi-mechanistic mathematical framework for simulating multi-hormone dynamics in reproductive endocrinology. Computational and Structural Biotechnology Journal 2025;27:3654 View
- S A. Letter to the Editor Regarding the Article ‘Feasibility Study of an Efficient Plan Pool Adaptive Radiotherapy Technology Based on Low-dose Computed Tomography for Cervical Cancer’. Clinical Oncology 2025;46:103919 View
- Sharma H, Kaur S. Patient-Specific Digital Twins for Personalized Healthcare: A Hybrid AI and Simulation-Based Framework. IEEE Access 2025;13:143277 View
- Mendes A. The role of ‘digital twins’ in the development of drugs. Journal of Prescribing Practice 2025;7(9):368 View
- Xia J, Ning X, Jiang L, Li P, Huang J, Jiang W, Li W, Wang C, Zheng L, Jiang T. Visual analysis of quality management in Chinese drug clinical trials based on CiteSpace and COOC. Frontiers in Medicine 2025;12 View
- Khikhmetova K. Advances in Drug Discovery: Navigating Challenges and Embracing Innovation. Australian Journal of Biomedical Research 2025;1(1):aubm005 View
- Xames M, Topcu T, Parker S, Zagarese V, Epling J. Evaluating CFIR 2.0 in identifying digital twin implementation challenges in healthcare: bridging the dichotomy between engineering and healthcare communities. Frontiers in Digital Health 2025;7 View
- Faqeer H, Khajavi S. Digital Twin and Computer Vision Combination for Manufacturing and Operations: A Systematic Literature Review. Applied Sciences 2025;15(18):10157 View
- Vallée A, Moawad G, Feki A, Ayoubi J. Digital twins in fertility, assisted reproductive technology and pregnancy: a systematic review. Reproductive BioMedicine Online 2025:105281 View
- Khan N, Tanade C, Geddes J, Randles A. Establishing hemodynamic convergence framework for coronary digital twins under realistic dynamic heart rates. Physics of Fluids 2025;37(9) View
- Vallée A. Digital twins for cardiovascular diseases: towards personalised and sustainable care. Acta Cardiologica 2025;80(9):1055 View
- Lăzăroiu G, Gedeon T, Halicka K, Szpilko D. Generative artificial intelligence-driven medical digital twin technologies in blockchain Internet of Things wearable sensor and computer vision-based extended reality healthcare metaverse. Engineering Management in Production and Services 2025;17(3):27 View
- Wang J, Mo F, Qiao S, Feng H, Lyu Z. Spatial computing in digital twins. Digital Twin 2025;2(2) View
- Zeng J, Tang X, Qin D, Yu L, Zhou X, Feng C, Mi J, Pan H, Wu J, Huang B, Wu A. Engineered GLP-1R-targeting nanoplatforms: multimodal therapeutics in human diseases. Journal of Nanobiotechnology 2025;23(1) View
- Luo X, Wang A, Zhang X, Huang K, Wang S, Chen L, Cui Y. Toward Intelligent AIoT: A Comprehensive Survey on Digital Twin and Multimodal Generative AI Integration. Mathematics 2025;13(21):3382 View
- Vallée A. Simulation-based model of menopause: hormonal changes and cardiovascular risk in a digital twin view. Climacteric 2025:1 View
- Zhang W, Lin H, Luan M, Wei P, Han Y. Digital vessel for the diagnosis of cardiovascular diseases. Vessel Plus 2025 View
- Siddiqui R, Lloyd D, Khan N. Integrating molecular pathogenesis and predictive modelling in granulomatous amoebic encephalitis due to Acanthamoeba : a digital twin framework for personalised therapy. Infectious Diseases 2025:1 View
- Menon G, Malave B, Mhaske M, Parjane S, Mhaismale H. Digital Twin Technologies in Medicine: The Innovations, Barriers, and Future Directions. Intelligent Hospital 2025:100043 View
- Xie T, Wang Z, He J, Zhang J. Applications of AI in the management of elderly diabetes patients. Ageing Research Reviews 2026;114:102960 View
Books/Policy Documents
- Thapliyal K, Thapliyal M, Thapliyal D. Digitalization and the Transformation of the Healthcare Sector. View
- Arya S, Aggarwal S, Ansar S. Blockchain and Digital Twin for Smart Hospitals. View
- Ashwini A, Santhiya G, Balasubramaniam S. AI-Powered Digital Twins for Predictive Healthcare. View
- Lavanya M, Ashwini A, Balasubramaniam S. AI-Powered Digital Twins for Predictive Healthcare. View
- Kuppusamy P. AI-Powered Digital Twins for Predictive Healthcare. View
- Kanematsu H, Barry D. Applications of Metaverse and Virtual Reality to Creative Education and Industry. View
- Torgersen L, Zehnder E, Ask T, Schulz S. HCI for Cybersecurity, Privacy and Trust. View
- Khatri R, Aryan P. Metaverse and Digital Twins. View
- VAIDHEHI M, MALATHY C, SUDHAKARAN P, CHERIAN A, GEETHA R, KUMAR G. Driving Innovation through AI and Digital Twin for 6G Powered Sustainable Ultra Smart Cities. View
- . Creating Responsible Inquiring Digital Health Organizations. View
- Prashar A, Singh M, Sharma S, Kuna S, Putha S, Gudekota S, Nimmagadda V, Joshi R. Proceedings of International Conference on Computational Complexity and Intelligent Algorithms. View
- Awotunde J, Adeniyi A, Randle O, Abiodun M, Falola P. HealthTech Horizons: AI-Infused Metaverse Solutions for Smart Healthcare Systems. View
- Adeyemo A, Ajibola O, Adeniyi A, Olayiwola S, Alabi A, Abiodun A, Adegboye O. HealthTech Horizons: AI-Infused Metaverse Solutions for Smart Healthcare Systems. View
- SOMADE O, GUDUR R, CHAUDHARY N, ALATE M. AI‐driven Innovations in Physiotherapy and Oncology 1. View
- Alaref E. Industry 4.0 - Transforming the Future Beyond Manufacturing [Working Title]. View
Conference Proceedings
- de Almeida V, de Oliveira D, de Barros C, Scatena G, Queiroz Filho A, Siqueira F, Costa A, Gomi E, Mendoza L, Batista E, Muñoz C, Siqueira I, Barreira R, dos Santos I, Cardoso C, Ogasawara E, Porto F. Proceedings of the ACM/IEEE 27th International Conference on Model Driven Engineering Languages and Systems. A Digital Twin System for Oil And Gas Industry: A Use Case on Mooring Lines Integrity Monitoring View
- Arshad R, Chakhar S, Hedaux S, Williams N, Smart E, Simms C, Bolle J. 2024 International Conference on Decision Aid Sciences and Applications (DASA). A Digital Twin Based Framework to Enhance Productivity Processes in Retail Industry View
- Alimour S, Alrabeei M. 2024 11th International Conference on Software Defined Systems (SDS). A Novel Model for Digital Twins in Mental Health: The Biopsychosocial AI-Driven Digital Twin (BADT) Framework View
- Boopathy G, Aoki E, Norcéide F, Thompson C, Lewis E, Chandra K. 2025 IEEE International systems Conference (SysCon). Digital Engineering Framework for Promoting Health and Human Performance with Immersive Technology View
- Aggarwal P, N M, P K, Kalia P, J G, Das M. 2025 International Conference on Networks and Cryptology (NETCRYPT). Wearable Sensors and Systems for Personalized Healthcare Monitoring View
- Prokop K, Zielonka A, Połap D. 2025 International Joint Conference on Neural Networks (IJCNN). Lightweight segmentation neural network for infrastructure maintenance in industrial digital twins View
- Mohammad Alizadeh J, Kumar Patel M, Wu H. Proceedings of the ACM/IEEE International Conference on Connected Health: Applications, Systems and Engineering Technologies. DT4PCP: A Digital Twin Framework for Personalized Care Planning Applied to Type 2 Diabetes Management View
