Theoretical Frameworks and Concepts

Dynamic Personalized Optimization: An AI Functionality Framework for Digital Therapeutics

Dohyoung Rim

JMIR Med Inform 2026 (Mar 18); 14:e75256

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Updating the Good Reporting of a Mixed Methods Study (GRAMMS) Reporting Guidelines: Protocol for a Methodological Review and Modified Delphi Process

Sarah Munce, Sergi Fàbregues, Quan Nha Hong, Alicia O’Cathain, Timothy Guetterman, John Creswell, Cheryl Poth, Katie Dainty, Andrea C Tricco, Mandy M Archibald, Clementine Jarrett, Jennifer Boyle, Dorothy Luong, Frank Kiwanuka, Ahtisham Younas

JMIR Res Protoc 2026 (Mar 17); 15:e82364

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Effect of a Digital-Driven Physician-Pharmacist Collaborative Model for Diabetes in Primary Health Care: Cluster Randomized Trial

Jie Xiao, Qing Wang, Shenglan Tan, Lei Chen, Daxiong Xiang, Haiyan Yuan, Xia Li, Shuting Huang, Bingjie Tang, Yan Guo, Haiying Huang, Danhui Zhao, Yue Li, Li Wang, Qun Li, Juan Liu, Ping Xu

J Med Internet Res 2026 (Mar 13); 28:e77470

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Developing and Validating Measures of Structural Ableism to Improve Health Outcomes for the Disability Community: Protocol for a Mixed Methods Study

Rupa S Valdez, Bonnielin K Swenor, Franz Castro, Caroline Cerilli, Bailey A Middleton, Kara S Fitzgibbon, Ashley Shew, Varshini Varadaraj, Hari Srinivasan, Diana Cejas

JMIR Res Protoc 2026 (Mar 13); 15:e86976

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Strategic Governance of Artificial Intelligence–Enabled Clinical Algorithm Development: Formative Evaluation of the Semiautomatic Clinical Algorithm Development Framework

Sang Hyun Ahn, Junhewk Kim

JMIR Form Res 2026 (Mar 12); 10:e90273

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Analysis of Multilevel Factors Mobilizing the Spectrum of Interorganizational Knowledge Sharing for Facilitating Digital Transformation at Scale: Qualitative Study

Hajar Mozaffar, Robin Williams, Kathrin Cresswell

J Med Internet Res 2026 (Mar 12); 28:e83345

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International Clinical Practice Guidelines on Traditional Chinese Medicine Therapy for Dysmenorrhea: Development Protocol

Li Zhang, Xiao Liang, Junlu Chen, Yuhan Du, Huilan Du, Xiaohui Wang

JMIR Res Protoc 2026 (Mar 11); 15:e77423

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Bridging Population Patterns and Individual Prediction: Framework for Prospective Multimorbidity Study

Qianyao Zhang, Runtong Zhang, Weiguang Ma, Butian Zhao, Xiaomin Zhu

JMIR Med Inform 2026 (Mar 10); 14:e84261

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Harmonizing Logical Observation Identifiers Names and Codes (LOINC) Codes and Units in Real-World Oncology Data: Method Development and Evaluation

Parvati Naliyatthaliyazchayil, Travis Stenerson

JMIR Med Inform 2026 (Mar 09); 14:e81254

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AI-Driven Mental Health Support for Caregivers of Individuals With Alzheimer Disease: Systematic Literature Review and Development of a Conceptual Framework

Syeda Umme Salma, Chandra Rekha Renduchintala, Isa Siddique, Evelina Sterling, Sweta Sneha, Nazmus Sakib

JMIR Ment Health 2026 (Mar 06); 13:e79973

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Digital Twins for Just-in-Time Adaptive Interventions (JITAIs): Framework for Optimizing and Continually Improving JITAIs

Asim H Gazi, Daiqi Gao, Susobhan Ghosh, Ziping Xu, Anna L Trella, Predrag Klasnja, Susan A Murphy

J Med Internet Res 2026 (Mar 06); 28:e72830

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Important Ethical, Technical, and Epidemiological Considerations in an AI Tool Production (ETEPAI): Scoping Review

Boon How Chew, Kee Yuan Ngiam

JMIR AI 2026 (Mar 05); 5:e80340

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Implementation of Reference Framework for Preventive Care for Older Adults: Cross-sectional Qualitative Study

Claire Chenwen Zhong, Mingtao Chen, Chung Yi Lo, Man Kin YIM, Xiaoshu Zhang, William CW Wong, Junjie Huang, Martin CS Wong

J Med Internet Res 2026 (Mar 04); 28:e78814

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Localized Immune Cascade Programming in Desmoplastic Tumors: In Silico Modeling and Validation Study

Murad Novruzov, Marziyya Mammadova, Keval Raval, Waseem Ullah Khan, Ulkar Shiraliyeva

JMIRx Bio 2026 (Feb 27); 4:e85507

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Scalable Agile Framework for Execution in AI for Medical AI Ethics Policy Design in Small- and Medium-Sized Enterprises

Ion Nemteanu, Adir Mancebo Jr, Leslie Joe, Ryan Lopez, Patricia Lopez, Warren Woodrich Pettine

J Med Internet Res 2026 (Feb 25); 28:e80028

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Effectiveness and Theoretical Foundations of mHealth Apps for Physical Activity, Healthy Eating, and Weight Loss: Protocol for a Systematic Review and Meta-Analysis

Victoria Riccalton, Madison Milne-Ives, Rosiered Brownson-Smith, Ananya Ananthakrishnan, Cen Cong, Emily Oliver, Edward Meinert

JMIR Res Protoc 2026 (Feb 17); 15:e72664

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Integration of the Integrate, Design, Assess, and Share Framework in Developing the Environmental Health Literacy Toolkit Paraben-Free & Me: Protocol for a Randomized Controlled Trial

Graziella De Michino, Satveer Dhillon, Caroline Barakat

JMIR Res Protoc 2026 (Feb 13); 15:e85474

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AI-Enhanced Continuing Professional Development as an Evolving Sociotechnical System: Multimethod Theoretical Framework Development Study

Vjekoslav Hlede, Sofia Valanci, G Robert D'Antuono, Heather Dow, Ronan O'Beirne, Richard Wiggins

JMIR Med Educ 2026 (Feb 12); 12:e69156

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Barriers to Digital Health Adoption in Older Adults: Scoping Review Informed by Innovation Resistance Theory

Yosefa Birati, Roy Tzemah-Shahar

J Med Internet Res 2026 (Feb 02); 28:e75591

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Extended Grammar of Systematized Nomenclature of Medicine – Clinical Terms for Semantic Representation of Clinical Data: Methodological Study

Christophe Gaudet-Blavignac, Julien Ehrsam, Monika Baumann, Adel Bensahla, Mirjam Mattei, Yuanyuan Zheng, Christian Lovis

J Med Internet Res 2026 (Jan 28); 28:e80314

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