Drug Repurposing and Off-Label Use

The Identification of Potential Drugs for Dengue Hemorrhagic Fever: Network-Based Drug Reprofiling Study

Praveenkumar Kochuthakidiyel Suresh, Gnanasoundari Sekar, Kavya Mallady, Wan Suriana Wan Ab Rahman, Wan Nazatul Shima Shahidan, Gokulakannan Venkatesan

JMIR Bioinform Biotech 2023 (May 09); 4:e37306

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Social Media Mining of Long-COVID Self-Medication Reported by Reddit Users: Feasibility Study to Support Drug Repurposing

Jonathan Koss, Sabine Bohnet-Joschko

JMIR Form Res 2022 (Oct 03); 6(10):e39582

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COVID-19 Treatments Sold Online Without Prescription Requirements in the United States: Cross-sectional Study Evaluating Availability, Safety and Marketing of Medications

Sachiko Ozawa, Joanna Billings, Yujiao Sun, Sushan Yu, Benjamin Penley

J Med Internet Res 2022 (Feb 16); 24(2):e27704

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A Venomics Approach to the Identification and Characterization of Bioactive Peptides From Animal Venoms for Colorectal Cancer Therapy: Protocol for a Proof-of-Concept Study

Syeda Kiran Shahzadi, Noushad Karuvantevida, Yajnavalka Banerjee

JMIR Res Protoc 2021 (Dec 21); 10(12):e31128

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ClinicalTrials.gov as a Source of Information About Expanded Access Programs: Cohort Study

Jan Borysowski, Andrzej Górski

J Med Internet Res 2021 (Oct 28); 23(10):e26890

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Pharmacokinetics and Perceptions of Children and Young Adults Using Cannabis for Attention-Deficit/Hyperactivity Disorder and Oppositional Defiant Disorder: Protocol for a Mixed Methods Proof-of-Concept Study

Holly Mansell, Declan Quinn, Lauren E Kelly, Michael Szafron, Jane Alcorn

JMIR Res Protoc 2021 (Oct 18); 10(10):e31281

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Combining Ketamine and Internet-Based Cognitive Behavioral Therapy for the Treatment of Posttraumatic Stress Disorder: Protocol for a Randomized Controlled Trial

Aaron Emile Philipp-Muller, Taras Reshetukha, Gustavo Vazquez, Roumen Milev, Dawn Armstrong, Jasleen Jagayat, Nazanin Alavi

JMIR Res Protoc 2021 (Jul 20); 10(7):e30334

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Self-reported Subjective Effects of Analytically Confirmed New Psychoactive Substances Consumed by e-Psychonauts: Protocol for a Longitudinal Study Using a New Internet-Based Methodology

Marc Grifell, Guillem Mir Fuster, Mireia Ventura Vilamala, Liliana Galindo Guarín, Xoán Carbón Mallol, Carl L Hart, Víctor Pérez Sola, Francesc Colom Victoriano

JMIR Res Protoc 2021 (Jul 02); 10(7):e24433

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Treatment of Barth Syndrome by Cardiolipin Manipulation (CARDIOMAN) With Bezafibrate: Protocol for a Randomized Placebo-Controlled Pilot Trial Conducted in the Nationally Commissioned Barth Syndrome Service

Lucy Dabner, Guido E Pieles, Colin G Steward, Julian P Hamilton-Shield, Andrew R Ness, Chris A Rogers, Chiara Bucciarelli-Ducci, Rosemary Greenwood, Lucy Ellis, Karen Sheehan, Barnaby C Reeves

JMIR Res Protoc 2021 (May 31); 10(5):e22533

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Impact of Trump's Promotion of Unproven COVID-19 Treatments and Subsequent Internet Trends: Observational Study

Kacper Niburski, Oskar Niburski

J Med Internet Res 2020 (Nov 23); 22(11):e20044

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Toward Preparing a Knowledge Base to Explore Potential Drugs and Biomedical Entities Related to COVID-19: Automated Computational Approach

Junaed Younus Khan, Md Tawkat Islam Khondaker, Iram Tazim Hoque, Hamada R H Al-Absi, Mohammad Saifur Rahman, Reto Guler, Tanvir Alam, M Sohel Rahman

JMIR Med Inform 2020 (Nov 10); 8(11):e21648

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No Time to Waste: Real-World Repurposing of Generic Drugs as a Multifaceted Strategy Against COVID-19

Moshe Rogosnitzky, Esther Berkowitz, Alejandro R Jadad

JMIRx Med 2020 (Sep 30); 1(1):e19583

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Artificial Intelligence for Rapid Meta-Analysis: Case Study on Ocular Toxicity of Hydroxychloroquine

Matthew Michelson, Tiffany Chow, Neil A Martin, Mike Ross, Amelia Tee Qiao Ying, Steven Minton

J Med Internet Res 2020 (Aug 17); 22(8):e20007

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Understanding Drug Repurposing From the Perspective of Biomedical Entities and Their Evolution: Bibliographic Research Using Aspirin

Xin Li, Justin F. Rousseau, Ying Ding, Min Song, Wei Lu

JMIR Med Inform 2020 (Jun 16); 8(6):e16739

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Delivering Benefits at Speed Through Real-World Repurposing of Off-Patent Drugs: The COVID-19 Pandemic as a Case in Point

Moshe Rogosnitzky, Esther Berkowitz, Alejandro R Jadad

JMIR Public Health Surveill 2020 (May 13); 6(2):e19199

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Drug Repositioning to Accelerate Drug Development Using Social Media Data: Computational Study on Parkinson Disease

Mengnan Zhao, Christopher C Yang

J Med Internet Res 2018 (Oct 11); 20(10):e271

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Using Social Media Data to Identify Potential Candidates for Drug Repurposing: A Feasibility Study

Majid Rastegar-Mojarad, Hongfang Liu, Priya Nambisan

JMIR Res Protoc 2016 (Jun 16); 5(2):e121

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Opportunities for Web-based Drug Repositioning: Searching for Potential Antihypertensive Agents with Hypotension Adverse Events

Kejian Wang, Mei Wan, Rui-Sheng Wang, Zuquan Weng

J Med Internet Res 2016 (Apr 01); 18(4):e76

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