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Published on in Vol 28 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/88570, first published .
Woman uses phone to view HIV self-test instructions from Self-Cov by National Department of Health.

Acceptability, Usability, and Clinical Appropriateness of an AI-Powered Tool for Linkage to HIV Services After HIV Self-Testing in South Africa: Mixed Methods Evaluation

Acceptability, Usability, and Clinical Appropriateness of an AI-Powered Tool for Linkage to HIV Services After HIV Self-Testing in South Africa: Mixed Methods Evaluation

Nomsa Brightness Mahlalela   1 , BSocSci (Hons), MA ;   Onthatile Maboa   1 , BA, BSocSci, MA ;   Caroline Govathson   1 , BPharm (Hons), MSc, PhD ;   Laura Rossouw   1 , BCom, MCom, PhD ;   Lawrence Long   1, 2 , BBusSci, MCom, MSc, PhD ;   Ross Greener   1 , BSocSci, MSocSci ;   Sarah Morris   3 , BS ;   Shawna Cooper   3 , BA ;   Sasha Frade   4 , BA (Hons), MA, MM, PhD ;   Sophie Pascoe   1 , BSc, MSc, PhD ;   Candice Chetty-Makkan   1 , BSc, BSc (Hons), MA, PhD

1 Department of Internal Medicine, Health Economics and Epidemiology Research Office (HE²RO), School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

2 Department of Global Health, Boston University School of Public Health, Boston, MA, United States

3 Product & Strategy, Audere, Seattle, WA, United States

4 Research, Monitoring and Evaluation, Audere Africa, Johannesburg, Gauteng, South Africa

Corresponding Author:

  • Nomsa Brightness Mahlalela, BSocSci (Hons), MA
  • Department of Internal Medicine
  • Health Economics and Epidemiology Research Office (HE²RO), School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand
  • Sunnyside Office Park Building C
  • Johannesburg 2193
  • South Africa
  • Phone: 27 769822046
  • Email: nmahlalela@heroza.org