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Published on in Vol 28 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/85840, first published .
Woman reviews AI-powered systematic analysis on futuristic interface

Artificial Intelligence for Evidence Synthesis of Emerging Biologics to Improve Skeletal Health in Osteogenesis Imperfecta: Systematic Review and Meta-Analysis

Artificial Intelligence for Evidence Synthesis of Emerging Biologics to Improve Skeletal Health in Osteogenesis Imperfecta: Systematic Review and Meta-Analysis

Chengfei Li   1 * , MPH ;   Zonglin Dai   2, 3 * , PhD ;   Wing Chung Tang   4 , PhD ;   Zesen Gao   4 , MSc ;   Vivien Kin Yi Chan   1 , PhD ;   Mariana Ramirez-Posada   5, 6 , MD ;   Jiyeong Kim   5, 6 , PhD ;   Eleni Linos   5, 6 , DrPH ;   CL Cheung   1, 2 , PhD ;   Ian Chi Kei Wong   1, 7, 8, 9 , PhD ;   Dong Dong   10 , PhD ;   Michael To   3, 11, 12 , PhD ;   Dawn Craig   13 , PhD ;   Xue Li   1, 2, 3 , PhD

1 Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong)

2 Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China (Hong Kong)

3 The University of Hong Kong–Shenzhen Hospital, Shenzhen, China

4 The University of Hong Kong Libraries, The University of Hong Kong, Hong Kong SAR, China (Hong Kong)

5 Department of Dermatology, Stanford School of Medicine, Stanford, CA, United States

6 Stanford Center for Digital Health, Department of Medicine, Stanford University, Stanford, CA, United States

7 Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China (Hong Kong)

8 School of Pharmacy, Aston University, Birmingham, United Kingdom

9 Macau University of Science and Technology, Macau Special Administrative Region, China

10 The Jockey Club School of Public Health and Primary Care (JCSPHPC),The Chinese University of Hong Kong, New Territories, Hong Kong SAR, China (Hong Kong)

11 Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China (Hong Kong)

12 Shenzhen Clinical Research Center for Rare Diseases, Shenzhen, China

13 Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom

*these authors contributed equally

Corresponding Author:

  • Xue Li, PhD
  • Department of Medicine, School of Clinical Medicine
  • Li Ka Shing Faculty of Medicine, The University of Hong Kong
  • PB306, Professorial Block, Queen Mary Hospital, 102 Pok Fu Lam Road
  • Hong Kong SAR
  • China (Hong Kong)
  • Phone: 852 2255 3319
  • Email: sxueli@hku.hk