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Published on in Vol 28 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/80119, first published .
Man preparing insulin pen with needle for diabetes management

Digital Engagement and Predictors of Semaglutide Persistence and Weight Loss in Severe Obesity: 48-Week Observational Study

Digital Engagement and Predictors of Semaglutide Persistence and Weight Loss in Severe Obesity: 48-Week Observational Study

Sarah Tournayre   1 , PharmD ;   Jean-baptiste Bonnet   1, 2 , MD ;   Jean Anitcheou   1, 2 ;   Marion Faivre   1 , MD ;   Catherine Boegner   1 , MD ;   Abdulkader Jalek   1 , MD ;   Dominique Jullien   1 , MD ;   Camille Le Rouzic   1 , MD ;   Vincent Attalin   1 , MD ;   Justine Myzia   1 , MD ;   Youadigue Kemba   1 , MD ;   Ariane Sultan   1, 3 , MD, PhD ;   Antoine Avignon   1, 2 , MD, PhD

1 Nutrition-Diabetes Department, Montpellier University Hospital, Centre Hospitalier Universitaire de Montpellier, Montpellier, France

2 Joint Research Unit (UMR) 1302, Desbrest Institute of Epidemiology and Public Health, University of Montpellier, INSERM, Université de Montpellier, Montpellier, France

3 PhyMedExp, INSERM U1046, National Centre for Scientific Research (CNRS) Joint Research Unit (UMR) 9214, University of Montpellier, Université de Montpellier, Montpellier, France

Corresponding Author:

  • Antoine Avignon, MD, PhD
  • Nutrition-Diabetes Department, Montpellier University Hospital, Centre Hospitalier Universitaire de Montpellier
  • 191 Avenue Du Doyen Gaston Giraud
  • Montpellier 34295
  • France
  • Phone: 33 467338402
  • Email: a-avignon@chu-montpellier.fr