Detection of Antithrombotic-Related Bleeding in Older Inpatients: Multicenter Retrospective Study Using Structured and Unstructured Electronic Health Record Data

Claire Coumau   ^{1, 2, 3} , PhD ;   Frederic Gaspar   ^{1, 2, 3} , PhD ;   Mehdi Zayene   ⁴ , MSc ;   Elliott Bertrand   ⁴ , MSc ;   Lorenzo Alberio   ⁵ , Prof Dr Med ;   Christian Lovis   ⁶ , Prof Dr Med ;   Patrick E Beeler   ^{7, 8} , PD Dr med ;   Fabio Rinaldi   ^{9, 10, 11} , Prof Dr ;   Monika Lutters   ¹² , PhD ;   Marie-Annick Le Pogam   ^{13 *} , MD, PhD ;   Chantal Csajka   ^{1, 2, 3 *} , Prof Dr ;   SwissMADE Collaborators   ¹⁴

¹ Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland

² School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland

³ Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland

⁴ Artefact Company, Lausanne, Switzerland

⁵ Service of Haematology and Central Haematology Laboratory, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland

⁶ Division of Medical Information Sciences, Geneva University Hospitals and University of Geneva, Geneva, Switzerland

⁷ Division of Occupational and Environmental Medicine, Epidemiology, Biostatistics and Prevention Institute, University of Zurich and University Hospital Zurich, Zurich, Switzerland

⁸ Center for Clinical Research, University of Lucerne, Lucerne, Switzerland

⁹ Dalle Molle Institute for Artificial Intelligence Research, IDSIA USI-SUPSI, Lugano, Switzerland

¹⁰ SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland

¹¹ Faculty of Biology and Medicine, Fondazione Bruno Kessler, Trento, Italy

¹² Head of Hospital Pharmacy, Kantonsspital Aarau, Aarau, Switzerland

¹³ Department of Epidemiology and Health Systems, Unisanté, University Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland

¹⁴ See Acknowledgments

*these authors contributed equally