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Published on in Vol 28 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/101202, first published .
Pharmacist reviews anticoagulant dosing data on a computer dashboard in a pharmacy.

A Hybrid Rule-Based and Machine Learning–Based Clinical Decision Support System to Support Prescription Review: Development and External Validation Study

A Hybrid Rule-Based and Machine Learning–Based Clinical Decision Support System to Support Prescription Review: Development and External Validation Study

Jonghyun Jeong   1 * , PharmD ;   Kyu-Nam Heo   1, 2 * , PharmD, PhD ;   A Jeong Kim   3 , PhD ;   Jin Hee Baek   3 , MSc ;   Yun Hee Jo   3 , PhD ;   Sunghwan Kim   3 , MSc ;   Mingi Jo   4 , BSc ;   Young-Mi Ah   5 , PhD ;   Ji Min Han   6 , PhD ;   Sae Won Choi   7 , MD ;   Junho Song   4 , MSc ;   Sangil Min   8 , MD, PhD ;   Ju-Yeun Lee   1, 2 , PhD

1 College of Pharmacy, Seoul National University, Seoul, Republic of Korea

2 College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea

3 Department of Pharmacy, Seoul National University Hospital, Seoul, Republic of Korea

4 ZerOne AI Inc, Seoul, Republic of Korea

5 College of Pharmacy, Yeungnam University, Daegu, Republic of Korea

6 College of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea

7 Office of Hospital Information, Seoul National University Hospital, Seoul, Republic of Korea

8 Department of Surgery, Seoul National University Hospital, Seoul, Republic of Korea

*these authors contributed equally

Corresponding Author:

  • Ju-Yeun Lee, PhD
  • College of Pharmacy, Seoul National University
  • 1 Gwanak-ro, Gwanak-gu
  • Seoul 08826
  • Republic of Korea
  • Phone: 82-2-3668-7472
  • Email: jypharm@snu.ac.kr