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This paper is in the following e-collection/theme issue:

Digital Health Reviews (3853) mHealth for Symptom and Disease Monitoring, Chronic Disease Management (2445) Chatbots and Conversational Agents (1240) Chronic Conditions (567)

Published on in Vol 27 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/72309, first published .
Elderly hands using a smartphone, showing age and technology use.

Conversational Agents Supporting Self-Management in People With a Chronic Disease: Systematic Review

Conversational Agents Supporting Self-Management in People With a Chronic Disease: Systematic Review

Authors of this article:

Tessa F Peerbolte1 Author Orcid Image ;   Rozanne JA van Diggelen1 Author Orcid Image ;   Pieter van den Haak1 Author Orcid Image ;   Kim Geurts1 Author Orcid Image ;   Luc JW Evers1 Author Orcid Image ;   Bastiaan R Bloem1 Author Orcid Image ;   Nienke M de Vries1, 2 Author Orcid Image ;   Sanne W van den Berg1 Author Orcid Image
Article Authors Cited by (20) Tweetations Metrics

Journals

  1. Colakoglu S, Durmus M, Polat Z, Yildiz A, Sezgin E. User Engagement with A Multimodal Conversational Agent for Self-Care and Chronic Disease Management: A Retrospective Analysis. Journal of Medical Systems 2025;49(1) View
  2. Li J, Shi C. Who do we follow online? An experimental study on source clarity and social proximity in digital health communication. Frontiers in Public Health 2025;13 View
  3. Diaconescu B, Gurzu B, Sava C, Sava C, Sfarghiu I, Luchian D, Gurzu I. How can artificial intelligence be used within occupational medicine to identify early worker needs and improve workplace accommodation? A narrative review. Romanian Journal of Occupational Medicine 2025;76(1):6 View
  4. Łukasik A, Celebudzka M, Gut A. “Your Digital Doctor Will Now See You”: A Narrative Review of VR and AI Technology in Chronic Illness Management. Healthcare 2026;14(2):143 View
  5. Valles-Coral M, Pinedo L, Injante R, Navarro-Cabrera J, Quintanilla-Morales K, Saavedra S, Valverde-Iparraguirre J, Leveau-Barrera F, Gonzalez-Gonzalez N. Hybrid expert system for lifestyle recommendations in hypertensive patients. Frontiers in Artificial Intelligence 2026;9 View
  6. Han G, Lee H, Son Y. Natural language processing-based chatbots for chronic disease self-management: A systematic review of implementation and health outcomes. DIGITAL HEALTH 2026;12 View
  7. Rangan G. Treatment of Autosomal Dominant Polycystic Kidney Disease. Journal of the American Society of Nephrology 2026;37(6):1319 View
  8. Zhao Y, Miao Y, Luo Y, Guo R, Wang H, Wu Y. Safety guardrails in patient-facing large language model systems for chronic disease self-management: a realist review. International Journal of Medical Informatics 2026;218:106513 View
  9. Zhao Y, Guo R, Miao Y, Luo Y, Wang H, Wu Y. Behavior Change Content and Implementation of Large Language Model–Driven Conversational Agents in Cardiometabolic Care: Scoping Review. Journal of Medical Internet Research 2026;28:e89190 View
  10. Zhang L, Yang X, Li G. Application of Q-methodology in chronic disease research: a scoping review. BMC Medical Research Methodology 2026;26(1) View
  11. Gamus A, Chodick G, Blachar Y, Shalom T. Conversational Capacity in Triadic Telemedicine: A Conceptual Framework and Evidence Synthesis. Telemedicine and e-Health 2026 View
  12. Haghighi Z, Kazemi A, Beigi M. The effect of a self-management training based on the 5As model on the sexual satisfaction of Iranian women: A randomized clinical trial. Journal of Health Psychology 2026 View
  13. Tanaka K, Kobayashi Y, Nakamura T. The Social Life of Chronic Disease: How Illness Reshapes Identity, Relationships, Adaptation, and Long-Term Healthcare Engagement. International Journal of Social and Psychological Aspects of Healthcare 2026;6(1):36 View
  14. Zhang X, Zhang H, Zheng Y. Dual-Constrained Co-Planning of Virtual Health Avatars and User Interfaces for Older Adults with Chronic Diseases. Applied Sciences 2026;16(19):9695 View
  15. Carr A, Jenkins A, Gómez V, Lorenzo J, Moclair R, Pocchia J, Gandhi D, Miller K, Graves K, Jonklaas J. Symptom Management Following Radioactive Iodine Treatment in Adults With Thyroid Cancer: Usability Evaluation and Proof-of-Concept Study. JMIR Cancer 2026;12:e84151 View
  16. Wang F, Qiao H, Wu Y, He X, Ying L. Digital self-management for chronic disease care: a mini review of service integration, equity, and public health implementation priorities. Frontiers in Public Health 2026;14 View

Conference Proceedings

  1. Zhang M. Proceedings of the 2026 International Conference on Artificial Intelligence in Education Technology and Data Science. Research on the Design of Health Education Products Integrating Multimodal Interaction View
  2. Tamboli D, Canales R, You C, Reese P, Potluri V, Lok B. Proceedings of the 26th ACM International Conference on Intelligent Virtual Agents. Experiential Knowledge in Multi-Agent Virtual Health Systems: The Value of an Expert Patient Agent View
  3. Munz L, Kirschbaum A, Kania C, Fellerhoff T, Richert A. Companion Publication of the 28th International Conference on Multimodal Interaction. A Modular Reference Architecture for Patient-Facing Generative AI Health Coaches in Chronic Self-Management View
  4. Kim J, Heo D, Hwang H, You J, Suh B. Proceedings of the 2026 Companion of the Computer-Supported Cooperative Work and Social Computing. Between the Clinic and the Kitchen: A Constraint RAG Chatbot as Boundary Infrastructure for Dialysis Care View