This paper is in the following e-collection/theme issue:

Digital Health Reviews (1724) Machine Learning (2076) Natural Language Processing (917) Clinical Information and Decision Making (1915) Artificial Intelligence (2129) Decision Support for Health Professionals (1539) Diagnostic Tools in Mental Health (326)

Published on in Vol 23, No 5 (2021): May

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/15708, first published .
Machine Learning and Natural Language Processing in Mental Health: Systematic Review

Machine Learning and Natural Language Processing in Mental Health: Systematic Review

Machine Learning and Natural Language Processing in Mental Health: Systematic Review

Authors of this article:

Aziliz Le Glaz1 Author Orcid Image ;   Yannis Haralambous2 Author Orcid Image ;   Deok-Hee Kim-Dufor1 Author Orcid Image ;   Philippe Lenca2 Author Orcid Image ;   Romain Billot2 Author Orcid Image ;   Taylor C Ryan3 Author Orcid Image ;   Jonathan Marsh4 Author Orcid Image ;   Jordan DeVylder4 Author Orcid Image ;   Michel Walter1, 5 Author Orcid Image ;   Sofian Berrouiguet1, 2, 5, 6 Author Orcid Image ;   Christophe Lemey1, 2, 5 Author Orcid Image
Article Authors Cited by (372) Tweetations (9) Metrics

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  255. Sellier Silva M, Ahrens J, Meister F, Palaniyappan L. Speech and Language Markers as Longitudinal Predictors of Youth Mental Health: A Systematic Review. Early Intervention in Psychiatry 2025;19(10) View
  256. Cunningham P, Gilmore J, Naar S, Preston S, Eubanks C, Hubig N, McClendon J, Ghosh S, Ryan-Pettes S. De zwarte doos van gezinsgerichte behandelingen gaat open: een AI-raamwerk om de therapeutische alliantie en therapeutische empathie te onderzoeken. Gezinstherapie Wereldwijd 2025;36(4):398 View
  257. Toker I, Jansen S, Knoche J, Lorenz D. Digital innovations for sustainable radiology: Reducing waste, emissions, and inefficiencies in imaging workflows. DIGITAL HEALTH 2025;11 View
  258. Yeasmin S, Saha S, Khan Rony M, Akter Semi M, Das S, Rahman R, Khan R, Tasnim A, Hosen A. The role of AI-driven art therapy in supporting autism, mental health, and emotional well-being: An umbrella review. DIGITAL HEALTH 2025;11 View
  259. Hamada M, Nomura R, Akitomo T, Kusaka S, Iwamoto Y, Yamamoto S, Ogaya Y, Nakano K. Applications of artificial intelligence in tooth extraction: A systematic review. Journal of Dental Sciences 2025 View
  260. Kovac D, Novakova L, Mekyska J, Novotny K, Brabenec L, Klobusiakova P, Rektorova I. Digital speech biomarkers for assessing cognitive decline across neurodegenerative conditions. Computers in Biology and Medicine 2025;198:111251 View
  261. Patel D, Johnson A. Detecting Narcissistic Personality Disorder (NPD): A Hybrid Regex and NLP-Based AI Approach With Phase-Aware Classification. IEEE Access 2025;13:185011 View
  262. Bu W, Wu X, Wang C, Cai Y. Development and validation of a predictive nomogram for severe adverse drug reactions: a dual-center pharmacovigilance study. Frontiers in Pharmacology 2025;16 View
  263. Vanhée L, Scarpa S. Is Addiction Research Addicted to Artificial Intelligence? Mapping the Intersection of Artificial Intelligence, Substance Use and Mental Health Through a Bibliometric Analysis. Drug and Alcohol Review 2025 View
  264. Chang J, Tamayo Velasquez V, Waddell A. “Trying to Do No Harm”: exploring clinician concerns towards the use of AI for risk prediction in psychiatry. BMJ Digital Health & AI 2025;1(1):e000078 View
  265. Wagner M, Stephenson C, Jagayat J, Kumar A, Shirazi A, Alavi N, Omrani M. Using large language models as a scalable mental status evaluation technique. NPP—Digital Psychiatry and Neuroscience 2025;3(1) View
  266. Anjum R, Daud S, Bhatti G, Saddique F. Evaluation of AI-based mental health interventions using the grey relational analysis. Grey Systems: Theory and Application 2025:1 View
  267. Vispute D, Pawar U, Ghonge M, Shukla V, Garg L, Liu H, Tran T. Performance Comparison of Word Embedding and Sequential Models for Mental Health Classification. EPJ Web of Conferences 2025;341:01044 View
  268. K N, Karuveettil V, Pillai A, Jayachandran M, Pallaty P. Effectiveness of artificial intelligence-enhanced cognitive behavioral therapy compared to alternate non-pharmacological therapies in treating depression or anxiety among adults: a systematic review protocol. JBI Evidence Synthesis 2025 View
  269. So M, Sekizawa Y, Hashimoto S, Kashimura M, Yamakage H, Watanabe N. Effect of Artificial Intelligence-Based Natural Language Feedback on Engagement and Clinical Outcomes in Fully Self-Guided Internet-Based Cognitive Behavioral Therapy for Depression: Three-Arm Randomized Controlled Trial (Preprint). Journal of Medical Internet Research 2025 View
  270. Merayo N, Ayuso-Lanchares A, González-Sanguino C. Revealing Emotional Insights From Mental Health Discussions on Instagram and TikTok Using BERT Models. IEEE Transactions on Affective Computing 2025;16(4):3279 View
  271. Ghorbankhani M, Safara M. Artificial intelligence in depression diagnostics: A systematic review of methodologies and clinical applications. Artificial Intelligence in Medicine 2026;172:103320 View
  272. Hu J, Zhang S, Cai M, Ma M, Li S, Chen H, Yang S. LSTM-assisted optical fiber interferometric sensing: breaking the limitation of free spectral range. Light: Science & Applications 2025;14(1) View

Books/Policy Documents

  1. V. S. A. Machine Learning and Data Analytics for Predicting, Managing, and Monitoring Disease. View
  2. Chen X, Genc Y. Artificial Intelligence in HCI. View
  3. Nguyen N, Labonte-Lemoyne E, Gregoire Y, Radanielina-Hita M, Senecal S. HCI International 2022 – Late Breaking Posters. View
  4. Pangsrisomboon P, Pyae A, Thawitsri N, Liulak S. Well-Being in the Information Society: When the Mind Breaks. View
  5. Ayatollahi H. Data Science with Semantic Technologies. View
  6. Mishra S, Abbas M, Jindal K, Narayan J, Dwivedy S. Revolutions in Product Design for Healthcare. View
  7. Li R, Li H, Tang B, Au W. Current State of Art in Artificial Intelligence and Ubiquitous Cities. View
  8. Tan T, Lim S, Qiu Y, Miao C. Social Computing and Social Media: Design, User Experience and Impact. View
  9. Ahmed U, Lin J, Srivastava G. Advances in Knowledge Discovery and Data Mining. View
  10. Kumar V, Medda G, Recupero D, Riboni D, Helaoui R, Fenu G. Advances in Bias and Fairness in Information Retrieval. View
  11. Ozsonmez D, Acarman T. Intelligent Sustainable Systems. View
  12. Jay A. Transformational Leadership Styles for Global Leaders. View
  13. Lasisi R. Proceedings of the Future Technologies Conference (FTC) 2023, Volume 2. View
  14. Shoenbill K, Kasturi S, Mendonca E. Chronic Illness Care. View
  15. Hoor-Ul-Ain S, Khan A, Siddiqui S, Dey I. Computational Methods in Psychiatry. View
  16. Chahar R, Dubey A, Narang S. Advances in Communication and Applications. View
  17. Garg R, Gupta A. Advances in Data-Driven Computing and Intelligent Systems. View
  18. Daneshvar H, Boursalie O, Samavi R, Doyle T, Duncan L, Pires P, Sassi R. Artificial Intelligence for Medicine. View
  19. Afşin Y, Taşkaya Temizel T. Persuasive Technology. View
  20. Fallah A, Aghdam M. Nonlinear Approaches in Engineering Application. View
  21. Perna G, Alciati A, Nemeroff C. The American Psychiatric Association Publishing Textbook of Psychopharmacology. View
  22. Sotolář O, Plhák J, Šmahel D. Text, Speech, and Dialogue. View
  23. Aggarwal R, Singh G, Aggarwal E. Artificial Intelligence‐Enabled Blockchain Technology and Digital Twin for Smart Hospitals. View
  24. Jerlina I, Uma Maheswari M. Deep Sciences for Computing and Communications. View
  25. Chinnaiyan B, Balasubaramanian S, Jeyabalu M, Warrier G. Model Optimization Methods for Efficient and Edge AI. View
  26. Briganti G. Truth Unveiled. View
  27. Banu A, Balyan P, Nisamudheen N, Velayutham D, Balyan M, Jithesh P. Encyclopedia of Bioinformatics and Computational Biology. View
  28. Scarpino I, Vallelunga R. Encyclopedia of Bioinformatics and Computational Biology. View
  29. Vitthalkar P, Deshpande P, Aarsanal V, Chikkamath S, Nirmala S, Budihal S. ICT Systems and Sustainability. View
  30. Ellahi A. Innovative Trends Shaping Food Marketing and Consumption. View
  31. Kandpal V, Ozili P, Jeyanthi P, Ranjan D, Chandra D. Digital Finance and Metaverse in Banking. View
  32. Gargot T, Guneysu A, Cifuentes C, Orlandi S. Digital Mental Health. View
  33. Beg M, Verma M. Chatbots and Mental Healthcare in Psychology and Psychiatry. View
  34. Rani P, ur Rehman K, Yadav S, Hussein L. Demystifying the Role of Natural Language Processing (NLP) in Mental Health. View
  35. Mishra S, Chhetri T, Balakrishnan A, Roy S, Gurung K, Jeba Praba J, Georrge J. Artificial Intelligence in Healthcare Information Systems—Security and Privacy Challenges. View
  36. Carrasco-Rodríguez A, Albero-Verdú S. Transformations in Digital Learning and Educational Technologies. View
  37. Zhang S, Li S, Zhang T, Zhang X, Geng Y, Lin H, Luo L, Yang L. Health Information Processing. View
  38. Elkhatibi Y, Boussedra F. Leveraging AI-Powered Marketing in the Experience-Driven Economy. View
  39. Ghiloufi H, Merveille N, Mellouli S. Accelerating the Socio-Ecological Transition. View
  40. Kenny B, Robinson J, Núñez D. New Perspectives on Suicidal Behavior. View
  41. Georgiadi M, Tomprou D, Inglezaki I, Meramveliotakis I, Plexousakis S. AI in Learning, Educational Leadership, and Special Education. View
  42. Chandra Sekar P, Veerabathiran R. The Palgrave Encyclopedia of Disability. View
  43. Aprahamian H. Tutorials in Operations Research: Advances in Analytics and Operations Research: Improving Decisions to Secure the Future. View
  44. Bobo S, Kolonin A. Advances in Neural Computation, Machine Learning, and Cognitive Research IX. View
  45. Nagaraju M, Kakulapati V, Vaishnavi P, Neha A, Vaishnavi M. Proceedings of the 7th International Conference on Communications and Cyber Physical Engineering. View

Conference Proceedings

  1. Castanha J, Indrawati , Pillai S, Ramantoko G, Widarmanti T. 2022 International Conference on Advanced Creative Networks and Intelligent Systems (ICACNIS). A Systematic Literature Review on Natural Language Processing (NLP) View
  2. Huang X. 2022 IEEE International Conference on Electrical Engineering, Big Data and Algorithms (EEBDA). Ideal Construction of Chatbot Based on Intelligent Depression Detection Techniques View
  3. Shivahare B, Singh A, Uppal N, Rizwan A, Vaathsav V, Suman S. 2022 2nd International Conference on Innovative Sustainable Computational Technologies (CISCT). Survey Paper: Study of Natural Language Processing and its Recent Applications View
  4. Stiglic G, Musovic K, Gosak L, Fijacko N, Kocbek P. 2022 IEEE 10th International Conference on Healthcare Informatics (ICHI). Relevance of automated generated short summaries of scientific abstract: use case scenario in healthcare View
  5. Zain S, Mumtaz W. 2022 International Conference on Frontiers of Information Technology (FIT). Tri-model ensemble with Grid Search optimization for Bipolar Disorder Diagnosis View
  6. Jabir K, Raja A. 2022 8th International Conference on Advanced Computing and Communication Systems (ICACCS). A Comprehensive Survey on Various Cancer Prediction Using Natural Language Processing Techniques View
  7. BH S, K N, C D, P B, Duraipandian K, Rajan S, Sathiyanarayanan M. 2022 14th International Conference on COMmunication Systems & NETworkS (COMSNETS). Mental Health Analysis of Employees using Machine Learning Techniques View
  8. Schirmer M, Nolasco I, Mosca E, Xu S, Pfeffer J. Proceedings of the Nineteenth International Conference on Artificial Intelligence and Law. Uncovering Trauma in Genocide Tribunals View
  9. Mir A, Jerome N, Akshara R, Reddy S, Mohapatra S, Mohanty J. 2023 International Conference on Applied Intelligence and Sustainable Computing (ICAISC). Comparative Analysis of Mental Health disorder in Higher Education Students using Predictive Algorithms View
  10. Campos J, Machado R, Vieira M. 12th Latin-American Symposium on Dependable and Secure Computing. Leveraging Time Series Autocorrelation Through Numerical Differentiation for Improving Failure Prediction View
  11. Anekar D, Deshpande Y, Suryawanshi R, Waman R, Divekar V, Salunke R. 2023 4th IEEE Global Conference for Advancement in Technology (GCAT). Exploring Emotion and Sentiment Landscape of Depression: A Multimodal Analysis Approach View
  12. Kadam D, Reddy K. 2023 1st DMIHER International Conference on Artificial Intelligence in Education and Industry 4.0 (IDICAIEI). A Study of Machine Learning Models for Predicting Mental Health Through Text Analysis View
  13. Dixit K, Pundir S, Shrivastava A, Kumar C, Srivastava A, Singh P. 2023 10th IEEE Uttar Pradesh Section International Conference on Electrical, Electronics and Computer Engineering (UPCON). Analyzing Textual Data for Mental Health Assessment: Natural Language Processing for Depression and Anxiety View
  14. E N, Juliet S. 2023 8th International Conference on Communication and Electronics Systems (ICCES). Comparative Analysis of Machine Learning Techniques for Mental Health Prediction View
  15. Lohia A, Ranjith A, Sachdeva A, Bhat A. 2023 7th International Conference on Intelligent Computing and Control Systems (ICICCS). An Ensemble Technique to Analyse Mental Health of Workforce in the Corporate Sector View
  16. Yong J, Koh J, Liew J, Tan C. 2024 3rd International Conference on Digital Transformation and Applications (ICDXA). Linguistic Harmony in Diversity: Lemmatizing Rojak Malay for Global Communication View
  17. Mishra K, Bodkhe H, Naik R, Bangalkar N, Dubey P. 2023 International Conference on Artificial Intelligence for Innovations in Healthcare Industries (ICAIIHI). Advancements in Conversational AI: Building Mental Health Chatbot with BERT Model View
  18. Yang Y, Viranda T, Van Meter A, Choudhury T, Adler D. Extended Abstracts of the CHI Conference on Human Factors in Computing Systems. Exploring Opportunities to Augment Psychotherapy with Language Models View
  19. Supriya M, Aniket A, M R, J A, Peter K. 2024 International Conference on Distributed Computing and Optimization Techniques (ICDCOT). AI-Powered Mental Health Diagnosis: A Comprehensive Exploration of Machine and Deep Learning Techniques View
  20. M.B. N, G.S. G. 2024 Third International Conference on Distributed Computing and Electrical Circuits and Electronics (ICDCECE). Leveraging Natural Language Processing for In-Depth Analysis and Insights from Hospital Patient Feedback Data View
  21. Kopitar L, Stiglic G, Bedrac L, Bian J. 2024 IEEE 12th International Conference on Healthcare Informatics (ICHI). Personalized Meal Planning in Inpatient Clinical Dietetics Using Generative Artificial Intelligence: System Description View
  22. Zhang T, Teng S, Jia H, D'Alfonso S. Companion of the 2024 on ACM International Joint Conference on Pervasive and Ubiquitous Computing. Leveraging LLMs to Predict Affective States via Smartphone Sensor Features View
  23. Huang S, Fu F, Yang K, Zhang K, Yang F. 2024 IEEE 4th International Conference on Software Engineering and Artificial Intelligence (SEAI). Empowerment of Large Language Models in Psychological Counseling through Prompt Engineering View
  24. Aygün İ, Kaya M. 2024 10th International Conference on Smart Computing and Communication (ICSCC). Prediction of the Most Common Symptoms in Psychological Illnesses with Language Representation Models View
  25. Schneider P, Mikołajewski D, Bryniarska A, Igras-Cybulska M, Cybulski A, Marcinowicz W, Janiszewski M, Kawala-Sterniuk A. 2024 Progress in Applied Electrical Engineering (PAEE). Methods and tools for automatic or semi-automatic recognition of selected emotions using machine learning algorithms View
  26. Siswanto V, Overbeek M. ETLTC2024 INTERNATIONAL CONFERENCE SERIES ON ICT, ENTERTAINMENT TECHNOLOGIES, AND INTELLIGENT INFORMATION MANAGEMENT IN EDUCATION AND INDUSTRY. Development of “kata terikat” detection and writing errors correction using Rabin-Karp and random forest algorithm View
  27. Nanda M, Inkpen D, Dargel A. 2024 28th International Conference Information Visualisation (IV). Detecting Multiple Mental Health Disorders with Large Language Models View
  28. Liao L. 2024 3rd International Conference on Artificial Intelligence and Computer Information Technology (AICIT). Application of Natural Language Processing Technology in Computer Education View
  29. Lin E, Sun J, Chen H, Mahoor M. 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). Data Quality Matters: Suicide Intention Detection on Social Media Posts Using RoBERTa-CNN View
  30. Tang J, Shang Y. 2024 IEEE 6th International Conference on Cognitive Machine Intelligence (CogMI). Advancing Mental Health Pre-Screening: A New Custom GPT for Psychological Distress Assessment View
  31. Shen Y, Yu X, Liao X. 2024 4th International Conference on Educational Technology (ICET). Assessment and Intervention for Children with Autism: Are AI Technology Interventions Effective? View
  32. Shan R. 2024 IEEE 4th International Conference on Data Science and Computer Application (ICDSCA). A Hybrid Ensemble Approach for Depression Detection: Combining Deep Learning and Machine Learning View
  33. Kumar K, Verma A, Verma P, Tripathi S. 2024 IEEE International Conference of Electron Devices Society Kolkata Chapter (EDKCON). Unveiling Mental Stress: Examining the Impact on College Students' Well-being Using Machine Learning Based Solutions View
  34. Alrjoob H, Alazaidah R, Batyha R, Khafajeh H, Elsoud E, Saeb Al-Sherideh A, Elrashidi A, Alqaraleh M, Amer W. 2024 25th International Arab Conference on Information Technology (ACIT). Classifying Psychiatric Patients Using Machine Learning View
  35. Shnain A, Ameer S, Al-Chalabi H, Muhsin A. 2024 International Conference on Emerging Research in Computational Science (ICERCS). Enhancing School-Based Prevention Programs Through Social and Emotional Learning Development View
  36. G A, S G, S M M, Mithuna S. 2025 International Conference on Electronics and Renewable Systems (ICEARS). Personalized Recommendations System for Mental Health Support using NLP View
  37. Raghuwanshi V, Gaikwad N, Bharti V, Bhargava V. 2025 IEEE International Students' Conference on Electrical, Electronics and Computer Science (SCEECS). Artificial Intelligence Enhanced Mental Care Platform SAARTHI View
  38. Kahate S, Pise G, Pawar K, Navghare N. 2024 2nd International Conference on Artificial Intelligence Trends and Pattern Recognition (ICAITPR). Enhancing Social Media Sentiment Analysis through Blockchain-Enabled Validation View
  39. Mylordick C, Petersen K, Meiliana , Zakiyyah A. 2024 International Conference on Informatics, Multimedia, Cyber and Information System (ICIMCIS). Embedded AI for Psychological Index Recognition Through Text Typing View
  40. Sayis B, Gao R, Song S, Gunes H. 2024 12th International Conference on Affective Computing and Intelligent Interaction Workshops and Demos (ACIIW). Learning Graph Representation for Predicting Student Mental Wellbeing in Robot Assisted Journal Writing Context View
  41. Petti U, Nyrup R, Skopek J, Korhonen A. 2023 ACM Conference on Fairness Accountability and Transparency. Ethical considerations in the early detection of Alzheimer's disease using speech and AI View
  42. Gorrepati L, Sonani R, Velugubantla V, Potla R, Sathvik M. Companion Proceedings of the ACM on Web Conference 2025. Mental Health and Relations: Detection of Mental Health Disorders Related to Relationship Issues Through Reddit Posts View
  43. Bhattacharjee A, Xu S, Rao P, Zeng Y, Meyerhoff J, Ahmed S, Mohr D, Liut M, Mariakakis A, Kornfield R, Williams J. Proceedings of the 2025 ACM Designing Interactive Systems Conference. Perfectly to a Tee: Understanding User Perceptions of Personalized LLM-Enhanced Narrative Interventions View
  44. Peixoto J, Lyra J, Passos A, Pereira B, Gouveia A, Araujo V. Anais do VI Workshop sobre as Implicações da Computação na Sociedade (WICS 2025). Bridging AI and Psychology: A RAG-Driven Approach to Inhibitory Control and ADHD Interventions View
  45. B S, R H, Alapati P, Othman N, P S, Rao V. 2025 Global Conference in Emerging Technology (GINOTECH). Enhancing Automated English Speaking Tests: The Integration of Natural Language Processing and Machine Learning View
  46. Singh N, Aryan A, Dhiman R, Rana M. 2025 6th International Conference on Intelligent Communication Technologies and Virtual Mobile Networks (ICICV). AI-Powered Mental Health Tracking With Smartwatch Integration for Instantaneous Stress Assessment and Assistance View
  47. M P A, Menon P, Namitha K. 2025 11th International Conference on Communication and Signal Processing (ICCSP). AI-Driven Behavioral Analysis of Aggression in Indian Tribal Adolescents View
  48. Vispute D, Pawar U. FIRST INTERNATIONAL CONFERENCE ON ADVENT TRENDS IN COMPUTATIONAL INTELLIGENCE AND COMMUNICATION TECHNOLOGIES: ICATCICT2024. Exploring deep learning and machine learning approaches for mental health status prediction: A review View
  49. Odutusin M, Malik H. 2025 IEEE International Conference on Industry 4.0, Artificial Intelligence, and Communications Technology (IAICT). A Novel Narrative Analysis Approach for Digital Content Using Natural Language Processing View
  50. Shakeel H, Ahmad T, Saxena C. 2025 IEEE 41st International Conference on Data Engineering Workshops (ICDEW). Holistix: A Dataset for Holistic Wellness Dimensions Analysis in Mental Health Narratives View
  51. Yu X. 2025 International Conference on Intelligent Computing and Knowledge Extraction (ICICKE). Intelligent Assessment of College Students' Mental Health based on Hybrid Decision Tree Algorithm View
  52. Stevanus A, Desanti R. 2025 International Conference on Information and Communication Technology (ICoICT). Comparative Analysis of SVM and LSTM for Detecting Early Suicide Ideation on Social Media View
  53. Zhang H, Fu X. Proceedings of the 3rd International Workshop on Multimodal and Responsible Affective Computing. Zero-shot Emotion Annotation in Facial Images Using Large Multimodal Models: Benchmarking and Prospects for Multi-Class, Multi-Frame Approaches View
  54. Khan Z, Garg A, Tahir A, Hewage P. 2025 12th International Conference on Reliability, Infocom Technologies and Optimization (Trends and Future Directions) (ICRITO). Emotion-Based Performance Monitoring System Using NLP View

Dissertations

  1. . The Social Media Influence on Childhood Obesity and Children’s Diets. View