Drug Repurposing and Off-Label Use

Articles published in this theme: 30 (scroll down to load remaining articles)

2026

View image

Immunotherapy Safety in Thymic Epithelial Tumors: Disproportionality Analysis of the Food and Drug Administration Adverse Event Reporting System

Ruilian Chen, Hanrui Chen, Lingling Sun, Yang Cao, Lizhu Lin

JMIR Cancer 2026 (Feb 25); 12:e76908

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

2025

View image

Antidepressant and Antipsychotic Drug Use and Cancer Risk: Protocol for an Overview of Systematic Reviews and Meta-Analyses

Joan Vicent Sánchez-Ortí, Jaume Forés-Martos, Vui Doan, Pablo Vicente-Martínez, Diego Macías Saint-Gerons, María Flores-Rodero, Jon Sánchez-Valle, Patricia Correa-Ghisays, Vicent Balanzá-Martínez, Pau Soldevila-Matías, Joan Vila-Francés, Emilio Soria-Olivas, Alfonso Valencia, Rafael Tabarés-Seisdedos

JMIR Res Protoc 2025 (Dec 23); 14:e78596

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

Lilian Bot, Josine G van Mill, Laetitia J C A Smarius, Adriaan W Hoogendoorn, Bram W C Storosum, Christiaan H Vinkers, Gabriel E Jacobs, Gert Jan Lammers, Hanna M Heller, Jantine C A Colen-de Koning, Joris J B van der Vlugt, Marloes S Oudijn, Martijn S van Noorden, Pierre M Bet, Rolf Fronczek, Heleen S van der Heijden, Sjors M M Lange, Ysbrand D van der Werf, Eric R van Exel

JMIR Res Protoc 2025 (Jul 24); 14:e68356

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

Detection of Clinically Significant Drug-Drug Interactions in Fatal Torsades de Pointes: Disproportionality Analysis of the Food and Drug Administration Adverse Event Reporting System

Huanhuan Ji, Meiling Gong, Li Gong, Ni Zhang, Ruiou Zhou, Dongmei Deng, Ya Yang, Lin Song, Yuntao Jia

J Med Internet Res 2025 (Mar 25); 27:e65872

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

Impact of Preventive Intravenous Amiodarone on Reperfusion Ventricular Fibrillation in Patients With Left Ventricular Hypertrophy Undergoing Open-Heart Surgery: Randomized Controlled Clinical Trial

Chan-Juan Gong, Xiao-Kai Zhou, Zhen-Feng Zhang, Yin Fang

JMIR Form Res 2025 (Jan 13); 9:e64586

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

2024

View image

Association Between X/Twitter and Prescribing Behavior During the COVID-19 Pandemic: Retrospective Ecological Study

Scott A Helgeson, Rohan M Mudgalkar, Keith A Jacobs, Augustine S Lee, Devang Sanghavi, Pablo Moreno Franco, Ian S Brooks, National COVID Cohort Collaborative (N3C)

JMIR Infodemiology 2024 (Nov 18); 4:e56675

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

Multifactor Quality and Safety Analysis of Semaglutide Products Sold by Online Sellers Without a Prescription: Market Surveillance, Content Analysis, and Product Purchase Evaluation Study

Amir Reza Ashraf, Tim Ken Mackey, Róbert György Vida, Győző Kulcsár, János Schmidt, Orsolya Balázs, Bálint Márk Domián, Jiawei Li, Ibolya Csákó, András Fittler

J Med Internet Res 2024 (Nov 07); 26:e65440

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

The Alzheimer’s Knowledge Base: A Knowledge Graph for Alzheimer Disease Research

Joseph D Romano, Van Truong, Rachit Kumar, Mythreye Venkatesan, Britney E Graham, Yun Hao, Nick Matsumoto, Xi Li, Zhiping Wang, Marylyn D Ritchie, Li Shen, Jason H Moore

J Med Internet Res 2024 (Apr 18); 26:e46777

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

The Efficacy of Bepotastine Besilate Compared With Hydroxyzine Pamoate for Preventing Infusion Reactions to the First Dose of Rituximab in Patients With Non-Hodgkin Lymphoma: Protocol for a Phase II, Double-Blind, Multicenter Randomized Trial

Yumi Kitahiro, Kazuhiro Yamamoto, Kimikazu Yakushijin, Takeshi Ioroi, Masaaki Tanda, Kotaro Itohara, Tomohiro Omura, Hironobu Minami, Ikuko Yano

JMIR Res Protoc 2024 (Feb 22); 13:e54882

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

2023

View image

Using Transformer-Based Topic Modeling to Examine Discussions of Delta-8 Tetrahydrocannabinol: Content Analysis

Brandi Patrice Smith, Brooke Hoots, Lara DePadilla, Douglas R Roehler, Kristin M Holland, Daniel A Bowen, Steven A Sumner

J Med Internet Res 2023 (Dec 21); 25:e49469

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

Drug Repurposing for Cancers With Limited Survival: Protocol for a Retrospective Cohort Study

Alejandro Rodríguez-Molinero, Carlos Pérez-López, Jose L Salazar González, Esther Garcia-Lerma, Juan A Álvarez-García, Luis M Soria Morillo, Tomás Salas Fernández

JMIR Res Protoc 2023 (Nov 14); 12:e48925

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

The Efficacy, Safety, and Efficiency of the Off-Label Use of Bevacizumab in Patients Diagnosed With Age-Related Macular Degeneration: Protocol for a Systematic Review and Meta-Analysis

João Estarreja, Priscila Mendes, Carina Silva, Pedro Camacho, Vanessa Mateus

JMIR Res Protoc 2023 (Jun 09); 12:e38658

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

The Identification of Potential Drugs for Dengue Hemorrhagic Fever: Network-Based Drug Reprofiling Study

Praveenkumar Kochuthakidiyel Suresh, Gnanasoundari Sekar, Kavya Mallady, Wan Suriana Wan Ab Rahman, Wan Nazatul Shima Shahidan, Gokulakannan Venkatesan

JMIR Bioinform Biotech 2023 (May 09); 4:e37306

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

2022

View image

Social Media Mining of Long-COVID Self-Medication Reported by Reddit Users: Feasibility Study to Support Drug Repurposing

Jonathan Koss, Sabine Bohnet-Joschko

JMIR Form Res 2022 (Oct 03); 6(10):e39582

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

COVID-19 Treatments Sold Online Without Prescription Requirements in the United States: Cross-sectional Study Evaluating Availability, Safety and Marketing of Medications

Sachiko Ozawa, Joanna Billings, Yujiao Sun, Sushan Yu, Benjamin Penley

J Med Internet Res 2022 (Feb 16); 24(2):e27704

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

2021

View image

A Venomics Approach to the Identification and Characterization of Bioactive Peptides From Animal Venoms for Colorectal Cancer Therapy: Protocol for a Proof-of-Concept Study

Syeda Kiran Shahzadi, Noushad Karuvantevida, Yajnavalka Banerjee

JMIR Res Protoc 2021 (Dec 21); 10(12):e31128

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

ClinicalTrials.gov as a Source of Information About Expanded Access Programs: Cohort Study

Jan Borysowski, Andrzej Górski

J Med Internet Res 2021 (Oct 28); 23(10):e26890

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

Pharmacokinetics and Perceptions of Children and Young Adults Using Cannabis for Attention-Deficit/Hyperactivity Disorder and Oppositional Defiant Disorder: Protocol for a Mixed Methods Proof-of-Concept Study

Holly Mansell, Declan Quinn, Lauren E Kelly, Michael Szafron, Jane Alcorn

JMIR Res Protoc 2021 (Oct 18); 10(10):e31281

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

Combining Ketamine and Internet-Based Cognitive Behavioral Therapy for the Treatment of Posttraumatic Stress Disorder: Protocol for a Randomized Controlled Trial

Aaron Emile Philipp-Muller, Taras Reshetukha, Gustavo Vazquez, Roumen Milev, Dawn Armstrong, Jasleen Jagayat, Nazanin Alavi

JMIR Res Protoc 2021 (Jul 20); 10(7):e30334

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section

View image

Self-reported Subjective Effects of Analytically Confirmed New Psychoactive Substances Consumed by e-Psychonauts: Protocol for a Longitudinal Study Using a New Internet-Based Methodology

Marc Grifell, Guillem Mir Fuster, Mireia Ventura Vilamala, Liliana Galindo Guarín, Xoán Carbón Mallol, Carl L Hart, Víctor Pérez Sola, Francesc Colom Victoriano

JMIR Res Protoc 2021 (Jul 02); 10(7):e24433

Download Citation: END BibTex RIS

Share on Bluesky Share on Twitter Share on Facebook Share on LinkedIn

View abstract

Download PDF Download XML

Go back to the top of the page Skip and go to footer section