Engagement with and Adherence to Digital Health Interventions, Law of Attrition

Digital Engagement Significantly Enhances Weight Loss Outcomes in Adults With Obesity Treated With Tirzepatide: Retrospective Cohort Study of a Digital Weight Loss Service

Hans Johnson, Ashley Kieran Clift, Daniel Reisel, David Huang

J Med Internet Res 2026 (Jan 15); 28:e83718

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Digital Health Interventions to Support Chronic Disease Management: Systematic Scoping Review

Abdullah Al Mahmud, Shane Joachim, Prem Prakash Jayaraman, Caitlin Learmonth, Shivani Tyagi, Abdur Rahim Mohammad Forkan, Muhammad Shuakat, Nilmini Wickramasinghe, Jack Wheeler, Stephanie Best, Alison Trainer

JMIR Mhealth Uhealth 2026 (Jan 14); 14:e63742

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Developing a Customizable Texting Intervention for Diabetes Self-Management: Participatory Design Approach

Stephanie A Robinson, Popy Shell, Linda Am, Courtney L Bilodeau, Howard S Gordon, Constance R Uphold, Varsha G Vimalananda, Sarah L Cutrona, Timothy P Hogan, Bridget Smith, Stephanie L Shimada

JMIR Form Res 2026 (Jan 13); 10:e83144

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Dropout, Attrition, Adherence, and Compliance in Mood Monitoring and Ambulatory Assessment Studies for Depression and Bipolar Disorder: Systematic Review and Meta-Analysis

Laurence Astill Wright, James Roe, Boliang Guo, Richard Morriss

JMIR Ment Health 2026 (Jan 12); 13:e83765

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Establishment and Optimization of a Patient-Reported Outcome–Based Electronic-Diary for Symptoms Evaluation in Patients With Gastroesophageal Reflux Disorder: Prospective Cohort Study

Yun-Chun Chen, Yen-Po Wang, Jui-Hsuan Hung, Da-Wei Wang, Shang-Liang Wu, Li-Fen Chen, Yueh-Hsin Ping, Mei-Lien Pan, Ching-Liang Lu

J Med Internet Res 2026 (Jan 06); 28:e83680

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Effect of AI-Based Natural Language Feedback on Engagement and Clinical Outcomes in Fully Self-Guided Internet-Based Cognitive Behavioral Therapy for Depression: 3-Arm Randomized Controlled Trial

Mirai So, Yoichi Sekizawa, Sora Hashimoto, Masami Kashimura, Hajime Yamakage, Norio Watanabe

J Med Internet Res 2026 (Jan 05); 28:e76902

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Determinants of Health Care Technology Adoption Using an Integrated Unified Theory of Acceptance and Use of Technology and Task Technology Fit Model: Systematic Review and Meta-Analysis

Ayesha Thanthrige, Bruce Lu, Zaid Sako, Nilmini Wickramasinghe

J Med Internet Res 2025 (Dec 30); 27:e64524

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Meta Self-Efficacy Internet Intervention to Support Occupational Health in Young Employees: Protocol for Co-Creation and a Randomized Controlled Trial

Jan Maciejewski, Roman Cieslak, Per Carlbring, Ewelina Smoktunowicz

JMIR Res Protoc 2025 (Dec 23); 14:e85082

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Implementation of a Mobile Digital Tool Supporting Medication for Opioid Use Disorder Treatment Improves Retention: Stepped-Wedge Cluster Randomized Controlled Trial

Jorge E Palacios, Robert Sherrick, Tim Janssen, Elana Deuble, Sara Lorenzen, Mark Schaefer, Jenna Tregarthen

J Med Internet Res 2025 (Dec 22); 27:e83346

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Evaluating the Reach, Usage, Human Support Needs, and Clinical Outcomes of Digital Parent Training for Child Oppositional Defiant Disorder Before and During Wartime: Longitudinal Study

Amit Baumel, Or Brandes, Chen R Saar

JMIR Pediatr Parent 2025 (Dec 22); 8:e80420

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Exploring the Fit Between the Outputs of Freely Available Medication Adherence Apps and Users’ Needs: Mixed Methods Study

Kirstin Messner, Vanessa Sutter, Samuel Allemann, Isabelle Arnet

JMIR Mhealth Uhealth 2025 (Dec 16); 13:e68919

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Smartphone App–Based Eating Behavior Monitoring and Feedback Intervention for Glucocorticoid-Induced Appetite Increase in Patients With Systemic Lupus Erythematosus: Protocol for a Pilot Randomized Controlled Trial

Takashi Yamaguchi, Nobuyuki Takahashi, Ryohei Inanaga, Ryuhei So, Hiroe Kikuchi, Hisashi Noma, Hiroyuki Sasai, Kazuhiro Kamada, Tomohiro Sugimoto, Hiroshi Tsushima, Takanori Ichikawa, Hirofumi Miyake, Shunichi Fujita, Keisuke Ono, Yusuke Miwa, Anna Hasegawa, Naoki Suzuki, Akira Onishi, Toshihiro Matsui, Ryu Watanabe, Yasuhiro Hasegawa, Rei Ono, Takeo Isozaki, Yuichi Ishikawa, Nobuyuki Yajima, Noriaki Kurita

JMIR Res Protoc 2025 (Dec 15); 14:e78612

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Effects of Choice Set Sizes and Moderations of Anxiety and State Emotions on Mental Health Self-Care Uptake, Engagement, and User Experience: Experimental Study

Siu Kit Yeung, Florence H T Leung, Jason C M Lee, Gabriel Man Hin Cheung, Ching Wan Li, Winnie W S Mak

JMIR Hum Factors 2025 (Dec 15); 12:e71165

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The Role of Practitioner- and User-Set Goals in Engagement and Psychological Distress Among Kooth Digital Health Users: Retrospective Analysis

Jacqlyn Yourell, Jennifer Huberty, Terry Hanley, Louisa Salhi

JMIR Form Res 2025 (Dec 15); 9:e70818

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Proactively Delivered Digital Mental Health Support for Health Care Workers: Usability and Acceptability Evaluation

Lauren Southwick, Rachel Gonzales, Lisa Bellini, David A Asch, Nandita Mitra, Mohan Balachandran, Courtney Benjamin Wolk, Emily M Becker-Haimes, Rachel Kishton, Sarah Beck, Raina M Merchant, Anisk K Agarwal

JMIR Form Res 2025 (Dec 09); 9:e74086

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The Scale-Up of a Digital Health Intervention (Healthy Beginnings for HNEKids) Targeting the First 2000 Days: Protocol for a Randomized Controlled Trial

Alison L Brown, Nayerra Hudson, Jacklyn Jackson, Jessica Pinfold, Luke Wolfenden, Nicole Nathan, Rebecca Sewter, Sienna Kavalec, Lynda Davies, Sarah Young, Hannah McCormick, Sonya Stanley, Tessa Delaney, Christophe Lecathelinais, Paul Craven, Sinead Redman, Emma Cushing, Nguyet de Mello, Karen Lee, Rachel Sutherland

JMIR Res Protoc 2025 (Dec 05); 14:e81390

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Depression and Anxiety Outcomes in a Technology-Enabled Psychotherapy Practice: Retrospective Cohort Study

Nicholas R Forand, Jasmine Nettiksimmons, Margaret Anton, Raven Truxson, Karl Vanderwood, Brandn Green

JMIR Form Res 2025 (Dec 02); 9:e76264

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Acceptability of Health Information Technology by Health Care Professionals: Where We Are Now and How We Can Fill the Gap

Corinne Isnard-Bagnis, Stéphane Mouchabac, Riadh Lebib, Hervé Bismut, Pierre Alexis Geoffroy

J Med Internet Res 2025 (Dec 02); 27:e72184

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Personalizing a Weight Loss Program Using Cognitive-Behavioral Phenotypes to Improve Engagement and Weight Loss in Adults With Overweight or Obesity: Quasi-Experimental Study

Joanna Szypula, Andreas Jarvstad, Lucy Amelia Jones, Katy Tapper

JMIR Form Res 2025 (Dec 01); 9:e72645

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Interactive Conversational Agents to Improve Dietary Behaviors for Health Promotion: Mixed Systematic Review

Samira Amil, Marie-Pierre Gagnon, Alexandra Bédard, Sié Mathieu Aymar Romaric Da, Daniela Zavala Mora, Vicky Drapeau, Sophie Desroches

J Med Internet Res 2025 (Nov 28); 27:e78220

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