Real-Time Electronic Patient-Reported Outcome Monitoring With Digital Triage and Care-Team Integration in Early Breast Cancer: ENABLE Randomized Controlled Trial

Thomas M Deutsch   ^{1, 2} , PD Dr ;   Léa L Volmer   ³ , Dr ;   Manuel Feisst   ⁴ , PhD ;   Marcus Heise   ^{5, 6} , PhD ;   Kathrin Hassdenteufel   ¹ , Dr ;   Lara M Tretschock   ¹ , Dr ;   André Pfob   ^{1, 7} , Dr ;   Christiane Breit   ¹ , MD ;   Ekaterina Martynenko   ¹ , Dr ;   Stefan Stefanovic   ² , Prof Dr ;   Nima Ghalekhani   ⁵ , PhD ;   Stephanie Wallwiener   ⁸ , Prof Dr ;   Eva Kantelhardt   ⁵ , Prof Dr ;   Marlene Martin   ⁵ ;   Armin Bauer   ⁹ , PhD ;   Tjeerd M H Dijkstra   ⁹ , PhD ;   Laura L Michel   ¹⁰ , PD Dr ;   Tobias Engler   ³ , Dr ;   Andreas D Hartkopf   ³ , Prof Dr ;   Nico Pfeifer   ^{11, 12, 13} , PhD ;   Sara Y Brucker   ³ , Prof Dr ;   Andreas Schneeweiss   ^{10, 14} , Prof Dr ;   Markus Wallwiener   ⁵ , Prof Dr

¹ Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Baden Wuerttemberg, Germany

² Department of Gynecology and Obstetrics, Mannheim University Hospital, University of Heidelberg, Mannheim, Baden Wuerttemberg, Germany

³ Department of Womenʼs Health, University of Tübingen, Tübingen, Germany

⁴ Institute of Medical Biometry, University of Heidelberg, Heidelberg, Germany

⁵ Department of Gynecology, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

⁶ Institute of General Practice and Family Medicine, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

⁷ Breast Center Heidelberg, Hospital St. Elisabeth, Heidelberg, Germany

⁸ Department of Obstetrics and Prenatal Medicine, University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

⁹ Institute of Women’s Health GmbH, Tübingen, Germany

¹⁰ National Center for Tumor Diseases (NCT), Heidelberg, Germany

¹¹ Methods in Medical Informatics, Department of Computer Science, University of Tübingen, Tübingen, Germany

¹² Center for Innovative Care, University Hospital Tübingen, Tübingen, Germany

¹³ Institute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Germany

¹⁴ German Cancer Research Center (DKFZ), Heidelberg, Germany