Development and Validation of an Interpretable Machine Learning Model for Staging Helicobacter pylori–Initiated Intestinal-Type Gastric Cancer in the Correa Cascade: Cross-Sectional Study

Jiawei Tang   ^{1 *} , MMed ;   Huijin Chen   ^{2 *} , MD ;   Wenwen Zhang   ³ , MD ;   Alfred Chin Yen Tay   ¹ , PhD ;   Barry J Marshall   ¹ , MD ;   Cong Ma   ⁴ , PhD ;   Liang Wang   ^{5, 6, 7, 8} , PhD

¹ The Marshall Centre for Interventions in Infectious Disease, The University of Western Australia, Perth, Australia

² Department of Laboratory Medicine, Shengli Oilfield Central Hospital, Dongyin, Shandong, China

³ Department of Clinical Medicine, School of the 1st Clinical Medicine, Xuzhou Medical University, Xuzhou, Jiangsu, China

⁴ Marshall Research Centre for Medical Microbial Biotechnology, Department of Life Sciences, Faculty of Science, The Hong Kong Polytechnic University (PolyU), Hongkong, China (Hong Kong)

⁵ Department of Laboratory Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China

⁶ School of Medicine, South China University of Technology, Guangzhou, Guangdong, China

⁷ Department of Intelligent Medical Engineering, School of Medical Informatics and Engineering, Xuzhou Medical University, Xuzhou, Jiangsu, China

⁸ School of Molecular Sciences, School of Biomedical Sciences, The University of Western Australia, Perth, Australia

*these authors contributed equally