Clinical Laboratory Terminology Standardization for Semantic Interoperability Using a Large Language Model–Based Agent: Methodological Study

Lijuan Wu   ^{1, 2 *} , PHD ;   Jinxin Huang   ^{1 *} , BS ;   Hongnian Wang   ^{3 *} , PhD ;   Liyi Mai   ¹ , BS ;   Xueyun Zhan   ¹ , MS ;   Xinrong He   ¹ , BS ;   Xiaotang Zhang   ¹ , MS ;   Huiying Liang   ⁴ , PhD ;   Xin Li   ^{5, 6} , MD, PhD ;   Abdelouahab Bellou   ^{1, 5, 6, 7, 8} , MD, PhD

¹ Institute of Sciences in Emergency Medicine, Department of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China

² Medical Research Institute, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China

³ Key Laboratory of Digital-Intelligent Disease Surveillance and Health Governance, North Sichuan Medical College, Nanchong, China

⁴ Medical Big Data Center, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China

⁵ Department of Emergency Medicine, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong, China

⁶ Key Special Project of Intergovernmental International Science and Technology Innovation Cooperation, China-Algeria Joint Laboratory on Emergency Medicine and Immunology, Guangzhou, China

⁷ Department of Emergency Medicine, Wayne State University School of Medicine, Detroit, MI, United States

⁸ Global Network on Emergency Medicine, Brookline, MA, United States

*these authors contributed equally