Efficacy of A Virtual Agent–Based Digital Intervention (Echo App V2.0) for Patients With Alcohol Use Disorder: Randomized Controlled Trial

Shuo Li   ¹ , MSc ;   Dapeng Zhang   ² , MSc ;   Weicong Sang   ¹ , MD, PhD ;   Ruihua Li   ³ , MD ;   Wei Yuan   ³ , MD, PhD ;   Jingyang Liu   ¹ , MSc ;   Huixue Li   ² , BSc ;   Meimei Liu   ⁴ , MSc ;   Yunchun Zhang   ² , BSc ;   Bingqian Zhang   ⁵ , MSc ;   Qianying Wu   ¹ , MSc ;   Chuanning Huang   ¹ , MD ;   Haidi Shan   ¹ , PhD ;   Jiang Du   ¹ , MD, PhD ;   Haifeng Jiang   ¹ , MD, PhD ;   Na Zhong   ¹ , MD ;   Tianzhen Chen   ^{1 *} , MD, PhD ;   Min Zhao   ^{1 *} , MD, PhD

¹ Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine and School of Psychology, Shanghai, China

² Fuyang No. 3 People's Hospital, Fuyang, China

³ Shandong Mental Health Center, Jinan, Shandong, China

⁴ Peking University Sixth Hospital, Beijing, China

⁵ GOS-UCL Institute of Child Health, London, United Kingdom

*these authors contributed equally