Machine Learning Analysis of Sex Differences in Cardiovascular-Kidney-Metabolic Risk Factors and Prognosis Among Patients With Moderate-to-Severe Coronary Artery Calcification: Prospective Cohort Study

Zixiang Ye   ^{1, 2, 3} , MD ;   Enmin Xie   ^{1, 2, 3} , MD ;   Zhangyu Lin   ^{1, 2, 3} , MD ;   Chenxi Song   ^{1, 2, 3} , MD ;   Rui Zhang   ^{1, 2, 3} , MD ;   Hao-Yu Wang   ^{1, 2, 3} , MD ;   Shanshan Shi   ^{1, 2, 3} , MD ;   Zhiyong Zhao   ^{1, 2, 3} , MD ;   Hao Wang   ^{1, 2, 3} , MD ;   Lei Feng   ^{1, 2, 3 *} , MD ;   Kefei Dou   ^{1, 2, 3 *} , MD

¹ Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

² State Key Laboratory of Cardiovascular Disease, Beijing, China

³ Cardiometabolic Medicine Center, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

*these authors contributed equally