Impact of GPT-4–Generated Discharge Letters on Patients’ Medical Comprehension: Prospective Crossover Study

Friederike Holderried   ^{1 *} , MD ;   Alessandra Sonanini   ^{1 *} , MD ;   Christian Stegemann–Philipps   ¹ , MSc ;   Anne Herrmann–Werner   ¹ , MD ;   Philipp Spitzer   ² , MD ;   Martina Guthoff   ³ , MD ;   Nils Heyne   ⁴ , MD ;   Konstantin Sering   ¹ , PhD ;   Martin Holderried   ⁵ , MD ;   Felix Eisinger   ⁴ , MD

¹ Tübingen Institute for Medical Education (TIME), University of Tübingen, Tübingen, Germany

² Department of Psychiatry and Psychotherapy, University of Erlangen-Nürnberg, Erlangen, Germany

³ Nephrological Center Villingen-Schwenningen, Villingen-Schwenningen, Germany

⁴ Department of Diabetology, Endocrinology, Nephrology, University of Tübingen, Tübingen, Germany

⁵ Karlsruhe Municipal Hospital, Karlsruhe, Germany

*these authors contributed equally