Developing and Validating a Machine Learning Algorithm to Predict the Risk of Incident Opioid Use Disorder Among OneFlorida+ Patients: Prognostic Modeling Study

Jabed Al Faysal   ^{1, 2} , BSc, MSc ;   Weihsuan Lo-Ciganic   ^{3, 4, 5} , PhD ;   Walid F Gellad   ^{3, 4} , MD ;   Yonghui Wu   ⁶ , PhD ;   Christopher A Harle   ^{7, 8} , PhD ;   Khoa Nguyen   ⁹ , PharmD ;   James L Huang   ¹ , PhD ;   Gerald Cochran   ¹⁰ , PhD ;   Debbie L Wilson   ¹ , PhD ;   Stephanie AS Staras   ⁶ , PhD ;   Siegfried OF Schmidt   ¹¹ , MD, PhD ;   Eric I Rosenberg   ^{1, 12} , MD, MSPH ;   Danielle Nelson   ¹¹ , MD ;   Shunhua Yan   ¹ , MEd ;   Gary M Reisfield   ¹ , MD ;   William M Greene   ¹³ , MD ;   Courtney Kuza   ⁴ , PhD ;   Md Mahmudul Hasan   ^{1, 14} , PhD

¹ Department of Pharmaceutical Outcomes & Policy, University of Florida, Gainesville, FL, United States

² Computer Science and Engineering Discipline, Khulna University, Khulna, Bangladesh

³ Division of General Internal Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States

⁴ Center for Pharmaceutical Policy and Prescribing, University of Pittsburgh, Pittsburgh, PA, United States

⁵ Geriatric Research Education and Clinical Center, North Florida/South Georgia Veterans Health System, Gainesville, FL, United States

⁶ Department of Health Outcomes & Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL, United States

⁷ Department of Health Policy and Management, School of Public Health, Indiana University, Indianapolis, IN, United States

⁸ Regenstrief Institute, Indianapolis, IN, United States

⁹ Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, United States

¹⁰ Department of Internal Medicine, Division of Epidemiology, University of Utah, Salt Lake City, UT, United States

¹¹ Department of Community Health and Family Medicine, College of Medicine, University of Florida, Gainesville, FL, United States

¹² Department of Internal Medicine, College of Medicine, University of Florida, Gainesville, FL, United States

¹³ Department of Psychiatry, College of Medicine, University of Florida, Gainesville, FL, United States

¹⁴ Department of Information Systems and Operations Management, Warrington College of Business, University of Florida, Gainesville, FL, United States