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Published on in Vol 28 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/108392, first published .
Elderly woman with cane looking out a window

Electrocardiogram Embeddings Beyond Chronological Age for Prediagnostic Cognitive Impairment and Dementia: Development and External Validation Study

Electrocardiogram Embeddings Beyond Chronological Age for Prediagnostic Cognitive Impairment and Dementia: Development and External Validation Study

Yujeong Kim   1, 2 , PhD ;   Dong Won Kim   1, 2 , MS ;   Yu Rang Park   1 , PhD ;   Woo Jung Kim   2, 3, 4 , MD, PhD ;   Jaewoong Kim   1 , MS ;   Yujee Chang   1 , BE ;   Heeyeon Kwon   1 , BE ;   Dukyong Yoon   1, 2, 5, 6 , MD, PhD

1 Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea

2 Yonsei Institute for Digital Health, Yonsei University, Seoul, Republic of Korea

3 Department of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Gyeonggi-do, Republic of Korea

4 Yonsei BEYOND Lab, Yongin, Gyeonggi-do, Republic of Korea

5 Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States

6 Center for Digital Health, Yongin Severance Hospital, Yonsei University Health System, Yongin, Gyeonggi-do, Republic of Korea

Corresponding Author:

  • Dukyong Yoon, MD, PhD
  • Department of Biomedical Systems Informatics
  • Yonsei University College of Medicine
  • 50-1 Yonsei-ro, Seodaemun-gu
  • Seoul 03722
  • Republic of Korea
  • Phone: 82 31-5189-8450
  • Email: dukyong.yoon@yonsei.ac.kr