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This paper is in the following e-collection/theme issue:

Digital Health Reviews (1864) Digital Mental Health Interventions, e-Mental Health and Cyberpsychology (2335) Anxiety and Stress Disorders (1392) Chatbots and Conversational Agents (804) Clinical Mental Health Informatics (76)

Published on in Vol 27 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/78238, first published .
Generative AI Mental Health Chatbots as Therapeutic Tools: Systematic Review and Meta-Analysis of Their Role in Reducing Mental Health Issues

Generative AI Mental Health Chatbots as Therapeutic Tools: Systematic Review and Meta-Analysis of Their Role in Reducing Mental Health Issues

Generative AI Mental Health Chatbots as Therapeutic Tools: Systematic Review and Meta-Analysis of Their Role in Reducing Mental Health Issues

Authors of this article:

Qiyang Zhang1 Author Orcid Image ;   Renwen Zhang2 Author Orcid Image ;   Yiying Xiong3 Author Orcid Image ;   Yuan Sui3 Author Orcid Image ;   Chang Tong3 Author Orcid Image ;   Fu-Hung Lin3 Author Orcid Image
Article Authors Cited by (11) Tweetations (4) Metrics

Journals

  1. Zhang Q, Zhang R, Xiong Y, Sui Y, Tong C, Lin F. Generative AI Mental Health Chatbots as Therapeutic Tools: Systematic Review and Meta-Analysis of Their Role in Reducing Mental Health Issues. Journal of Medical Internet Research 2025;27:e78238 View
  2. Chung V, Bernier P, Hudon A. Mass Media Narratives of Psychiatric Adverse Events Associated With Generative AI Chatbots: Rapid Scoping Review. JMIR Mental Health 2026;13:e93040 View
  3. Chen S, Feucht M, Bhatt A, Farlow J. Artificial Intelligence in Head and Neck Surgical Oncology: A State-of-the-Art Review. Journal of Clinical Medicine 2026;15(7):2767 View
  4. Kéri S. Szimulált tudat, álempátia és kötődésillúzió: mit kezdhet a pszichiátria a mesterséges intelligenciával?. Orvosi Hetilap 2026;167(14):539 View
  5. Shoshani A, Gurfinkel B, Kor A, Ben-Haim Y, Kanarek O, Segev R, Shafir O, Arbel R. Efficacy of a Conversational AI Agent for Psychiatric Symptoms and Digital Therapeutic Alliance. JAMA Network Open 2026;9(4):e266713 View
  6. Schmidt R, Gonzalez S, St. George S, DiCamillo C, Horigian V. Shedding light on mental health problems and potential solutions for young women: results from an anonymous asynchronous online focus group. Frontiers in Psychiatry 2026;17 View
  7. Coulombe É, Hudon A, Paquin V. The Therapeutic Potential of Chatbots for Men Who Are Involuntarily Single: A Commentary on Lafortune et al. (2026). Archives of Sexual Behavior 2026 View
  8. Lialiou P, Katsiroumpa A, Gallos P, Konstantakopoulou O, Moisoglou I, Galani O, Tsiachri M, Galanis P. Exploring Nurses’ Perspectives on the Use of Artificial Intelligence Chatbots for Mental Health Support: A Cross-Sectional Study in Greece. Nursing Reports 2026;16(4):133 View
  9. Basantes Insuasti J, Corrales Vargas D, Villa Yánez V. Inteligencia Artificial Generativa como apoyo para la personalización de intervenciones terapéuticas para la depresión: una revisión exploratoria. Esprint Investigación 2026;5(1):754 View

Conference Proceedings

  1. Wang C, Zhang J, Zhou C. Proceedings of the Extended Abstracts of the 2026 CHI Conference on Human Factors in Computing Systems. Who Is More Willing to Form a Romantic Intimate Relationship with GAI? View
  2. N M, A M, K M. 2026 6th International Conference on Expert Clouds and Applications (ICOECA). Senti Bot: An AI-Driven Emotional Support and Crisis Intervention System using Multimodal Interaction View