Development and Evaluation of a Natural Language Processing Annotation Tool to Facilitate Phenotyping of Cognitive Status in Electronic Health Records: Diagnostic Study

Ayush Noori   ^{1 *} ;   Colin Magdamo   ^{1 *} , BSc ;   Xiao Liu   ¹ , MSc ;   Tanish Tyagi   ¹ ;   Zhaozhi Li   ¹ , MSc ;   Akhil Kondepudi   ¹ ;   Haitham Alabsi   ^{1, 2} , MD ;   Emily Rudmann   ^{1, 3} , BSc ;   Douglas Wilcox   ^{1, 2} , MD, PhD ;   Laura Brenner   ^{2, 4} , MD ;   Gregory K Robbins   ^{2, 5} , MD ;   Lidia Moura   ^{1, 2} , MD, PhD ;   Sahar Zafar   ^{1, 2} , MD ;   Nicole M Benson   ^{2, 6, 7} , MD, MBI ;   John Hsu   ^{2, 6} , MD, PhD ;   John R Dickson   ^{1, 2} , MD, PhD ;   Alberto Serrano-Pozo   ^{1, 2} , MD, PhD ;   Bradley T Hyman   ^{1, 2} , MD, PhD ;   Deborah Blacker   ^{2, 8} , MD, PhD ;   M Brandon Westover   ^{1, 2} , MD, PhD ;   Shibani S Mukerji   ^{1, 2, 5} , MD, PhD ;   Sudeshna Das   ^{1, 2} , PhD

¹ Department of Neurology, Massachusetts General Hospital, Boston, MA, US

² Harvard Medical School, Boston, MA, US

³ Vaccine and Immunotherapy Center, Division of Infectious Disease, Boston, MA, US

⁴ Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, US

⁵ Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, US

⁶ Mongan Institute, Massachusetts General Hospital, Boston, MA, US

⁷ McLean Hospital, Belmont, MA, US

⁸ Department of Psychiatry, Massachusetts General Hospital, Boston, MA, US

*these authors contributed equally