Published on in Vol 21, No 6 (2019): June

Preprints (earlier versions) of this paper are available at, first published .
Mobile Apps for Increasing Treatment Adherence: Systematic Review

Mobile Apps for Increasing Treatment Adherence: Systematic Review

Mobile Apps for Increasing Treatment Adherence: Systematic Review


  1. Llorens-Vernet P, Miró J. The Mobile App Development and Assessment Guide (MAG): Delphi-Based Validity Study. JMIR mHealth and uHealth 2020;8(7):e17760 View
  2. Manyazewal T, Woldeamanuel Y, Holland D, Fekadu A, Blumberg H, Marconi V. Electronic pillbox-enabled self-administered therapy versus standard directly observed therapy for tuberculosis medication adherence and treatment outcomes in Ethiopia (SELFTB): protocol for a multicenter randomized controlled trial. Trials 2020;21(1) View
  3. Goradia S, Holland R, Alexander S, Greenbaum D, Chen T, Aslani P. A new age intervention to support medication adherence. Research in Social and Administrative Pharmacy 2021;17(6):1204 View
  4. Nozdrachev D, Zamyatin K, Taratukhin E. Digital tools for improving medication adherence. Russian Journal of Cardiology 2019;(12):96 View
  5. Kardas P, Aguilar-Palacio I, Almada M, Cahir C, Costa E, Giardini A, Malo S, Massot Mesquida M, Menditto E, Midão L, Parra-Calderón C, Pepiol Salom E, Vrijens B. The Need to Develop Standard Measures of Patient Adherence for Big Data: Viewpoint. Journal of Medical Internet Research 2020;22(8):e18150 View
  6. Domańska B, Vansant S, Mountian I. A Companion App to Support Rheumatology Patients Treated with Certolizumab Pegol: Results From a Usability Study. JMIR Formative Research 2020;4(7):e17373 View
  7. Tonetti M, Deng K, Christiansen A, Bogetti K, Nicora C, Thurnay S, Cortellini P. Self‐reported bleeding on brushing as a predictor of bleeding on probing: Early observations from the deployment of an internet of things network of intelligent power‐driven toothbrushes in a supportive periodontal care population. Journal of Clinical Periodontology 2020;47(10):1219 View
  8. Amor-García M, Collado-Borrell R, Escudero-Vilaplana V, Melgarejo-Ortuño A, Herranz-Alonso A, Arranz Arija J, Sanjurjo-Sáez M. Assessing Apps for Patients with Genitourinary Tumors Using the Mobile Application Rating Scale (MARS): Systematic Search in App Stores and Content Analysis. JMIR mHealth and uHealth 2020;8(7):e17609 View
  9. Jessen S, Mirkovic J, Nes L. MyStrengths, a Strengths-Focused Mobile Health Tool: Participatory Design and Development. JMIR Formative Research 2020;4(7):e18049 View
  10. Gómez-del-Río N, González-González C, Toledo-Delgado P, Muñoz-Cruz V, García-Peñalvo F. Health Promotion for Childhood Obesity: An Approach Based on Self-Tracking of Data. Sensors 2020;20(13):3778 View
  11. Inal Y, Wake J, Guribye F, Nordgreen T. Usability Evaluations of Mobile Mental Health Technologies: Systematic Review. Journal of Medical Internet Research 2020;22(1):e15337 View
  12. Amir M, Feroz Z, Beg A, Rickles N. Using a pharmacist-led mHealth to improve patient’s adherence of antidepressants: patients’ experiences in low resourceful country. BMJ Innovations 2021;7(1):75 View
  13. Wittig-Wells D, Higgins M, Carter J, Holmes E, Jacob A, Samms-McPherson J, Sapp P, Sims S, Titus B, Haupt J, Holstad M. Impact of a Smartphone App Reminder on Adherence to Aspirin Prescribed as Antithrombotic Therapy. Orthopaedic Nursing 2020;39(6):395 View
  14. Ganju A, Satyan S, Tanna V, Menezes S. AI for Improving Children’s Health: A Community Case Study. Frontiers in Artificial Intelligence 2021;3 View
  15. Morse R, Myburgh H, Reubi D, Archey A, Busakwe L, Garcia-Prats A, Hesseling A, Jacobs S, Mbaba S, Meyerson K, Seddon J, van der Zalm M, Wademan D, Hoddinott G. Opportunities for Mobile App–Based Adherence Support for Children With Tuberculosis in South Africa. JMIR mHealth and uHealth 2020;8(11):e19154 View
  16. Pouls B, Vriezekolk J, Bekker C, Linn A, van Onzenoort H, Vervloet M, van Dulmen S, van den Bemt B. Effect of Interactive eHealth Interventions on Improving Medication Adherence in Adults With Long-Term Medication: Systematic Review. Journal of Medical Internet Research 2021;23(1):e18901 View
  17. Sala-González M, Pérez-Jover V, Guilabert M, Mira J. Mobile Apps for Helping Informal Caregivers: A Systematic Review. International Journal of Environmental Research and Public Health 2021;18(4):1702 View
  18. Pearsons A, Hanson C, Gallagher R, O’Carroll R, Khonsari S, Hanley J, Strachan F, Mills N, Quinn T, McKinstry B, McHale S, Stewart S, Zhang M, O’Connor S, Neubeck L. Atrial fibrillation self-management: a mobile telephone app scoping review and content analysis. European Journal of Cardiovascular Nursing 2021;20(4):305 View
  19. Delamarche E, Temiz Y, Lovchik R, Christiansen M, Schuerle S. Capillary Microfluidics for Monitoring Medication Adherence. Angewandte Chemie 2021;133(33):17928 View
  20. Vansimaeys C, Benamar L, Balagué C. Digital health and management of chronic disease: A multimodal technologies typology. The International Journal of Health Planning and Management 2021;36(4):1107 View
  21. Delamarche E, Temiz Y, Lovchik R, Christiansen M, Schuerle S. Capillary Microfluidics for Monitoring Medication Adherence. Angewandte Chemie International Edition 2021;60(33):17784 View
  22. Miró J, Llorens-Vernet P. Assessing the Quality of Mobile Health-Related Apps: Interrater Reliability Study of Two Guides. JMIR mHealth and uHealth 2021;9(4):e26471 View
  23. Bulaj G, Clark J, Ebrahimi M, Bald E. From Precision Metapharmacology to Patient Empowerment: Delivery of Self-Care Practices for Epilepsy, Pain, Depression and Cancer Using Digital Health Technologies. Frontiers in Pharmacology 2021;12 View
  24. Machalicek W, Strickland-Cohen K, Drew C, Cohen-Lissman D. Sustaining Personal Activism: Behavior Analysts as Antiracist Accomplices. Behavior Analysis in Practice 2022;15(4):1066 View
  25. Markad P, Takawale S, Lomate N, Mote P. Emergency Care APP – Analysis and Review. International Journal of Advanced Research in Science, Communication and Technology 2021:276 View
  26. Mira J. How to reduce medication errors in patients over the age of 65?. Expert Opinion on Pharmacotherapy 2021;22(18):2417 View
  27. Knisely B, Levine C, Vaughn-Cooke M, Wagner L, Fink J. Quantifying human performance for heterogeneous user populations using a structured expert elicitation. Safety Science 2021;143:105435 View
  28. Chen Y, Liao W, Su M, Lin Y. Personalized and Self-Management: Systematic Search and Evaluation Quality Factors and User Preference of Drug Reference Apps in Taiwan. Journal of Personalized Medicine 2021;11(8):790 View
  29. Khadam S, Chu T, Deekes N, FitzGerald D, Preston A, Duncan N. An investigation of the use of app technology to support clinical management of patients with chronic myeloid leukaemia (CML). Journal of Oncology Pharmacy Practice 2023;29(5):1083 View
  30. Kessler R, Kazdin A, Aguilar‐Gaxiola S, Al‐Hamzawi A, Alonso J, Altwaijri Y, Andrade L, Benjet C, Bharat C, Borges G, Bruffaerts R, Bunting B, de Almeida J, Cardoso G, Chiu W, Cía A, Ciutan M, Degenhardt L, de Girolamo G, de Jonge P, de Vries Y, Florescu S, Gureje O, Haro J, Harris M, Hu C, Karam A, Karam E, Karam G, Kawakami N, Kiejna A, Kovess‐Masfety V, Lee S, Makanjuola V, McGrath J, Medina‐Mora M, Moskalewicz J, Navarro‐Mateu F, Nierenberg A, Nishi D, Ojagbemi A, Oladeji B, O'Neill S, Posada‐Villa J, Puac‐Polanco V, Rapsey C, Ruscio A, Sampson N, Scott K, Slade T, Stagnaro J, Stein D, Tachimori H, ten Have M, Torres Y, Viana M, Vigo D, Williams D, Wojtyniak B, Xavier M, Zarkov Z, Ziobrowski H. Patterns and correlates of patient‐reported helpfulness of treatment for common mental and substance use disorders in the WHO World Mental Health Surveys. World Psychiatry 2022;21(2):272 View
  31. Maspero M, Hull T. Patient-Reported Outcomes in Colorectal Surgery. Clinics in Colon and Rectal Surgery 2023;36(04):240 View
  32. Knisely B, Vaughn-Cooke M, Wagner L, Fink J. Device personalization for heterogeneous populations: leveraging physician expertise and national population data to identify medical device patient user groups. User Modeling and User-Adapted Interaction 2021;31(5):979 View
  33. Bonn M, Alvarez L, Graham L, Thompson J, Dickey J. Biofeedback as an intervention for persistent post-concussive symptoms: A randomized feasibility trial. Journal of Concussion 2021;5:205970022110464 View
  34. LaValley S, Brady L, Nguyen M, Jacobs D. Family Caregivers of Older Adults: Strategies, Tools, and Technologies for Medication Management. Journal of Gerontological Social Work 2023;66(2):291 View
  35. Singer P. Post-transplant education for kidney recipients and their caregivers. Pediatric Nephrology 2023;38(7):2033 View
  36. García-Sánchez S, Somoza-Fernández B, de Lorenzo-Pinto A, Ortega-Navarro C, Herranz-Alonso A, Sanjurjo M. Mobile Health Apps Providing Information on Drugs for Adult Emergency Care: Systematic Search on App Stores and Content Analysis. JMIR mHealth and uHealth 2022;10(4):e29985 View
  37. Romero-Jimenez R, Escudero-Vilaplana V, Chamorro-de-Vega E, Ais-Larisgoitia A, Lobato-Matilla E, Somoza-Fernández B, Ruiz-Briones P, González C, Baniandrés O, Menchén L, Lobo-Rodríguez C, Herranz A, Sanjurjo M. Design and implementation of a mobile app for the pharmacotherapeutic follow-up of patients diagnosed with immune-mediated inflammatory diseases: eMidCare. Frontiers in Immunology 2022;13 View
  38. Vaitkienė G, Kuzborska Z, Žukauskienė M. Digital Health Solutions for Chronic Illnesses: A Systematic Review of Mobile Health Apps and Quality Analysis with Mobile App Rating Scale. Journal of Ageing and Longevity 2022;2(3):193 View
  39. Hogan T, Etingen B, Lipschitz J, Shimada S, McMahon N, Bolivar D, Bixler F, Irvin D, Wacks R, Cutrona S, Frisbee K, Smith B. Factors Associated With Self-reported Use of Web and Mobile Health Apps Among US Military Veterans: Cross-sectional Survey. JMIR mHealth and uHealth 2022;10(12):e41767 View
  40. D’Ambrosio F, Di Spirito F, De Caro F, Lanza A, Passarella D, Sbordone L. Adherence to Antibiotic Prescription of Dental Patients: The Other Side of the Antimicrobial Resistance. Healthcare 2022;10(9):1636 View
  41. Santo K. Can Digital Health Solutions Fill in the Gap for Effective Guideline Implementation in Cardiovascular Disease Prevention: Hope or Hype?. Current Atherosclerosis Reports 2022;24(9):747 View
  42. Shade M, Rector K, Kupzyk K. Voice Assistant Reminders and the Latency of Scheduled Medication Use in Older Adults With Pain: Descriptive Feasibility Study. JMIR Formative Research 2021;5(9):e26361 View
  43. Bascuñana-Ambrós H, Nadal-Castells M, Ramírez-Mirabal E, Beranuy-Rodriguez M, Pintor-Ojeda A, Perrot-González J. Emerging Concepts and Evidence in Telematics Novel Approaches or Treatments for Spasticity Management After Botulinum Injection. Frontiers in Rehabilitation Sciences 2021;2 View
  44. Knisely B, Vaughn-Cooke M. Accessibility Versus Feasibility: Optimizing Function Allocation for Accommodation of Heterogeneous Populations. Journal of Mechanical Design 2022;144(3) View
  45. Bendig J, Wolf A, Mark T, Frank A, Mathiebe J, Scheibe M, Müller G, Stahr M, Schmitt J, Reichmann H, Loewenbrück K, Falkenburger B. Feasibility of a Multimodal Telemedical Intervention for Patients with Parkinson’s Disease—A Pilot Study. Journal of Clinical Medicine 2022;11(4):1074 View
  46. Lewkowicz D, Wohlbrandt A, Bottinger E. Digital Therapeutic Care Apps With Decision-Support Interventions for People With Low Back Pain in Germany: Cost-Effectiveness Analysis. JMIR mHealth and uHealth 2022;10(2):e35042 View
  47. Moore T, Amado R. A Conceptual Model of Treatment Adherence in a Behavior Analytic Framework. Education and Treatment of Children 2021;44(1):1 View
  48. Chapman-Goetz J, Packham N, Gabb G, Potts C, Yu K, Prosser A, Hotham E, Suppiah V, Fukumoto Y. Acceptability and feasibility of the NPS MedicineWise mobile phone application in supporting medication adherence in patients with chronic heart failure: Protocol for a pilot study. PLOS ONE 2022;17(2):e0263284 View
  49. Astasio-Picado Á, Cobos-Moreno P, Gómez-Martín B, Verdú-Garcés L, Zabala-Baños M. Efficacy of Interventions Based on the Use of Information and Communication Technologies for the Promotion of Active Aging. International Journal of Environmental Research and Public Health 2022;19(3):1534 View
  50. Scherrenberg M, Marinus N, Giallauria F, Falter M, Kemps H, Wilhelm M, Prescott E, Vigorito C, De Kluiver E, Cipriano G, Dendale P, Hansen D. The need for long-term personalized management of frail CVD patients by rehabilitation and telemonitoring: A framework. Trends in Cardiovascular Medicine 2023;33(5):283 View
  51. Islam S, Mishra V, Siddiqui M, Moses J, Adibi S, Nguyen L, Wickramasinghe N. Smartphone Apps for Diabetes Medication Adherence: Systematic Review. JMIR Diabetes 2022;7(2):e33264 View
  52. Langarizadeh M, Nadjarzadeh A, Maghsoudi B, Fatemi Aghda S. The nutritional content required to design an educational application for infertile women. BMC Women's Health 2023;23(1) View
  53. Sun C, Liao G, Liao L, Chang L. A Cooperative Management App for Parents with Myopic Children Wearing Orthokeratology Lenses: Mixed Methods Pilot Study. International Journal of Environmental Research and Public Health 2021;18(19):10316 View
  54. Kosoku A, Iwai T, Masuda H, Kabei K, Nishide S, Maeda K, Yoshikawa Y, Nakamura Y, De Geest S, Uchida J. Reliability and Validity of the Japanese Version of the Basel Assessment of Adherence to Immunosuppressive Medications Scale in Kidney Transplant Recipients. Transplantation Direct 2023;9(3):e1457 View
  55. Pratiwi H, Kristina S, Widayanti A, Prabandari Y, Kusuma I. A Systematic Review of Compensation and Technology-Mediated Strategies to Maintain Older Adults’ Medication Adherence. International Journal of Environmental Research and Public Health 2023;20(1):803 View
  56. Martin-Payo R, Carrasco-Santos S, Cuesta M, Stoyan S, Gonzalez-Mendez X, Fernandez-Alvarez M. Spanish adaptation and validation of the User Version of the Mobile Application Rating Scale (uMARS). Journal of the American Medical Informatics Association 2021;28(12):2681 View
  57. Ottaviani A, Monteiro D, Oliveira D, Gratão A, Jacinto A, Campos C, Barham E, de Souza Orlandi F, da Cruz K, Corrêa L, Zazzetta M, Pavarini S. Usability and acceptability of internet-based interventions for family carers of people living with dementia: systematic review. Aging & Mental Health 2022;26(10):1922 View
  58. Yang L, Wu J, Mo X, Chen Y, Huang S, Zhou L, Dai J, Xie L, Chen S, Shang H, Rao B, Weng B, Abulimiti A, Wu S, Xie X. Changes in Mobile Health Apps Usage Before and After the COVID-19 Outbreak in China: Semilongitudinal Survey. JMIR Public Health and Surveillance 2023;9:e40552 View
  59. Siniarski A, Sobieraj P, Samel-Kowalik P, Sińska B, Milewska M, Bzikowska-Jura A. Nutrition-related mobile applications - Should they be used for dietary prevention and treatment of cardiovascular diseases?. Nutrition, Metabolism and Cardiovascular Diseases 2022;32(11):2505 View
  60. Phang Y, Heaukulani C, Martanto W, Morris R, Tong M, Ho R. Perceptions of a Digital Mental Health Platform Among Participants With Depressive Disorder, Anxiety Disorder, and Other Clinically Diagnosed Mental Disorders in Singapore: Usability and Acceptability Study. JMIR Human Factors 2023;10:e42167 View
  61. Tran B, Bui T, Do A, Boyer L, Auquier P, Nguyen L, Nguyen A, Ngo T, Latkin C, Zhang M, Ho C, Ho R. Efficacy of a Mobile Phone–Based Intervention on Health Behaviors and HIV/AIDS Treatment Management: Randomized Controlled Trial. Journal of Medical Internet Research 2023;25:e43432 View
  62. Kim S, Hwang H, Lee Y, Kim Y. A Systematic Review of Korea’s Medication Management Mobile Application. SAGE Open 2023;13(3) View
  63. Blasco J, Díaz-Díaz B, Igual-Camacho C, Pérez-Maletzki J, Hernández-Guilén D, Roig-Casasús S. Effectiveness of using a chatbot to promote adherence to home physiotherapy after total knee replacement, rationale and design of a randomized clinical trial. BMC Musculoskeletal Disorders 2023;24(1) View
  64. Borowska-Beszta A, Smieszek M, Borowska-Beszta B. Mobile banking apps in Poland and their accessibility for consumers with disabilities: a case study. Disability & Society 2023:1 View
  65. Chong C, Bakry M, Hatah E, Mohd Tahir N, Mustafa N. Effects of mobile apps intervention on medication adherence and type 2 diabetes mellitus control: A systematic review and meta-analysis. Journal of Telemedicine and Telecare 2023:1357633X2311749 View
  66. Fernández C, Vicente M, Guilabert M, Carrillo I, Mira J. Developing a mobile health app for chronic illness management: Insights from focus groups. DIGITAL HEALTH 2023;9 View
  67. Lewkowicz D, Bottinger E, Siegel M. Economic Evaluation of Digital Therapeutic Care Apps for Unsupervised Treatment of Low Back Pain: Monte Carlo Simulation. JMIR mHealth and uHealth 2023;11:e44585 View
  68. Assiri G, Alabdulkarim D, Alanazi A, Altamimi S, Alanazi N, Khawagi W. Description of patient characteristics and medication adherence among medication access mobile application users and nonusers: a single-center questionnaire-based cross-sectional study. BMC Digital Health 2023;1(1) View
  69. Park L, Ng F, Handley M. The use of the Capability-Opportunity- Motivation Behavior (COM-B) model to identify barriers to medication adherence and the application of mobile health technology in adults with coronary heart disease: A qualitative study. PEC Innovation 2023;3:100209 View
  70. Willems R, Annemans L, Siopis G, Moschonis G, Vedanthan R, Jung J, Kwasnicka D, Oldenburg B, d’Antonio C, Girolami S, Agapidaki E, Manios Y, Verhaeghe N, Usheva N, Iotova V, Triantafyllidis A, Votis K, Toti F, Makrilakis K, Seghieri C, Moreno L, Dupont S, Lewis L, Djokic D, Skouteris H. Cost effectiveness review of text messaging, smartphone application, and website interventions targeting T2DM or hypertension. npj Digital Medicine 2023;6(1) View
  71. Martin-Vicario L, Bustos Díaz J, Nicolas-Sans R, Yan Z. Weight Loss App Descriptors in App Stores: A Qualitative Analysis of the Spanish Market. Human Behavior and Emerging Technologies 2023;2023:1 View
  72. Che Pa M, Makmor-Bakry M, Islahudin F. Digital Health in Enhancing Antiretroviral Therapy Adherence: A Systematic Review and Meta-Analysis. AIDS Patient Care and STDs 2023;37(11):507 View
  73. Mohammadi Torkabad S, Negahban Bonabi T, Heidari S. Effectiveness of smartphone-based medication reminder application on medication adherence of patients with essential hypertension: A clinical trial study. Journal of Nursing and Midwifery Sciences 2020;7(4):219 View
  74. Mitchaï P, Mapinduzi J, Verbrugghe J, Michiels S, Janssens L, Kossi O, Bonnechère B, Timmermans A. Mobile technologies for rehabilitation in non-specific spinal disorders: a systematic review of the efficacy and potential for implementation in low- and middle-income countries. European Spine Journal 2023;32(12):4077 View
  75. Rozhnev V, Gorbunova E, Sadovnikov A, Lyapina I, Barbarash O. The Efficacy of the Smart-Rehabilitation Program in Patients After the Correction of Valvular Heart Diseases. Kardiologiia 2023;63(5):27 View
  76. Chapman-Goetz J, Packham N, Yu K, Gabb G, Potts C, Prosser A, Arstall M, Burdeniuk C, Chan A, Wilson T, Hotham E, Suppiah V. NPS MedicineWise application in supporting medication adherence in chronic heart failure: an acceptability and feasibility pilot study. Frontiers in Digital Health 2023;5 View
  77. Babaskin D, Zakharchenko M, Shestakov M, Litvinova T, Babaskina L, Glazkova I. Development of opportunities to provide medication treatment for seniors through mobile applications. Research Journal of Pharmacy and Technology 2023:4741 View
  78. González Robles M, López González M. Treatment abandonment-continuity factors. Community and Interculturality in Dialogue 2023;3:101 View
  80. Zvulunov A, Lenevich S, Migacheva N. A Mobile Health App for Facilitating Disease Management in Children With Atopic Dermatitis: Feasibility and Impact Study. JMIR Dermatology 2023;6:e49278 View
  81. Díaz-González Á, Fontanillas N, Gil-Hernández E, Guilabert M, Londoño M, Noguerol M, Pérez Escanilla F, Mira J, Santiñá M. Recomendaciones y criterios de calidad para mejorar el diagnóstico precoz de la colangitis biliar primaria. Gastroenterología y Hepatología 2023 View
  82. Khafid M, Bramantoro T, Hariyani N, Setyowati D, Palupi R, Ariawantara P, Pratamawari D, Pindobilowo P, Mohd Nor N. The Use of Internet of Things (IoT) Technology to Promote Children's Oral Health: A Scoping Review. European Journal of Dentistry 2024 View
  83. González-Suitt K, Püschel K, Escalona G, Varas J, Sateler J, Aravena H, Greig D, Rioseco A, Thompson B. Breaking the digital gap to reduce cardiovascular risk in primary care. Health Education Journal 2024 View
  84. Tan N, Goh C, Koh Y, Tan S, Ponraj D, Luo Z. Patient-caregiver twinned mobile phone application to promote medication adherence. Proceedings of Singapore Healthcare 2024;33 View
  85. Blasco J, Navarro-Bosch M, Aroca-Navarro J, Hernández-Guillén D, Puigcerver-Aranda P, Roig-Casasús S. A Virtual Assistant to Guide Early Postoperative Rehabilitation after Reverse Shoulder Arthroplasty: A Pilot Randomized Trial. Bioengineering 2024;11(2):152 View

Books/Policy Documents

  1. Ehrler F, Blondon K. Digital Health. View
  2. Mitchell I, Govias G. Asthma Education. View
  3. Atallah Z, JosephNg P, Loh Y. Proceedings of the 4th International Conference on Telecommunications and Communication Engineering. View
  4. Sorrell A, Stallings T, Christensen A. Encyclopedia of Mental Health. View
  5. Marinho C, Gomes O, da Silva Junior G, de Oliveira J, Schwingel P. Innovations in Nephrology. View
  6. Altuwayrib S, Win K, Freeman M. Persuasive Technology. View
  7. Pham T, Theng Y, Tan K, Lim J, Hong S, Mohamad N, Ting Valerie T. Human Aspects of IT for the Aged Population. View
  8. Patel R. Pharmaceutical Care in Digital Revolution. View