Published on in Vol 20, No 4 (2018): April

Preprints (earlier versions) of this paper are available at, first published .
The Efficacy of Electronic Health–Supported Home Exercise Interventions for Patients With Osteoarthritis of the Knee: Systematic Review

The Efficacy of Electronic Health–Supported Home Exercise Interventions for Patients With Osteoarthritis of the Knee: Systematic Review

The Efficacy of Electronic Health–Supported Home Exercise Interventions for Patients With Osteoarthritis of the Knee: Systematic Review


  1. Durst J, Roesel I, Sudeck G, Sassenberg K, Krauss I. Effectiveness of Human Versus Computer-Based Instructions for Exercise on Physical Activity–Related Health Competence in Patients with Hip Osteoarthritis: Randomized Noninferiority Crossover Trial. Journal of Medical Internet Research 2020;22(9):e18233 View
  2. Cohen S, Baber Z, Buvanendran A, McLean B, Chen Y, Hooten W, Laker S, Wasan A, Kennedy D, Sandbrink F, King S, Fowler I, Stojanovic M, Hayek S, Phillips C. Pain Management Best Practices from Multispecialty Organizations During the COVID-19 Pandemic and Public Health Crises. Pain Medicine 2020;21(7):1331 View
  3. Ankawi B, Kerns R, Edmond S. Enhancing Motivation for Change in the Management of Chronic Painful Conditions: a Review of Recent Literature. Current Pain and Headache Reports 2019;23(10) View
  4. Esbensen B, Kennedy N, Brodin N. Prevention and adherence in Rheumatic and Musculoskeletal disease. Best Practice & Research Clinical Rheumatology 2020;34(2):101525 View
  5. Safari R, Jackson J, Sheffield D. Digital Self-Management Interventions for People With Osteoarthritis: Systematic Review With Meta-Analysis. Journal of Medical Internet Research 2020;22(7):e15365 View
  6. Ballin M, Hult A, Björk S, Dinsmore J, Nordström P, Nordström A. Digital exercise interventions for improving measures of central obesity: a systematic review. International Journal of Public Health 2020;65(5):593 View
  7. Hossain M, Tasnim S, Sharma R, Sultana A, Shaik A, Faizah F, Kaur R, Uppuluri M, Sribhashyam M, Bhattacharya S. Digital interventions for people living with non-communicable diseases in India: A systematic review of intervention studies and recommendations for future research and development. DIGITAL HEALTH 2019;5:205520761989615 View
  8. de Thurah A, Bremander A, Primdahl J. High-quality RMD rehabilitation and telehealth: Evidence and clinical practice. Best Practice & Research Clinical Rheumatology 2020:101513 View
  9. Xie S, Wang Q, Wang L, Wang L, Song K, He C. Effect of Internet-Based Rehabilitation Programs on Improvement of Pain and Physical Function in Patients with Knee Osteoarthritis: Systematic Review and Meta-analysis of Randomized Controlled Trials. Journal of Medical Internet Research 2021;23(1):e21542 View
  10. Chen T, Or C, Chen J. Effects of technology-supported exercise programs on the knee pain, physical function, and quality of life of individuals with knee osteoarthritis and/or chronic knee pain: A systematic review and meta-analysis of randomized controlled trials. Journal of the American Medical Informatics Association 2021;28(2):414 View
  11. Tonga E, Williamson E, Srikesavan C, Özen T, Sarıtaş F, Lamb S. A hand exercise mobile app for people with rheumatoid arthritis in Turkey: design, development and usability study. Rheumatology International 2021;41(6):1151 View
  12. Lederman O, Furzer B, Wright K, McKeon G, Rosenbaum S, Stanton R. Mental Health Considerations for Exercise Practitioners Delivering Telehealth Services. Journal of Clinical Exercise Physiology 2021;10(1):20 View
  13. Daste C, Kirren Q, Akoum J, Lefèvre-Colau M, Rannou F, Nguyen C. Physical activity for osteoarthritis: Efficiency and review of recommandations. Joint Bone Spine 2021;88(6):105207 View
  14. Wang L, Xie S, Bao T, Zhu S, Liang Q, Wang X, Zhang R, Xiang X, Du C, He C. Exercise and education for community-dwelling older participants with knee osteoarthritis: a video-linked programme protocol based on a randomised controlled trial. BMC Musculoskeletal Disorders 2021;22(1) View
  15. Seron P, Oliveros M, Gutierrez-Arias R, Fuentes-Aspe R, Torres-Castro R, Merino-Osorio C, Nahuelhual P, Inostroza J, Jalil Y, Solano R, Marzuca-Nassr G, Aguilera-Eguía R, Lavados-Romo P, Soto-Rodríguez F, Sabelle C, Villarroel-Silva G, Gomolán P, Huaiquilaf S, Sanchez P. Effectiveness of Telerehabilitation in Physical Therapy: A Rapid Overview. Physical Therapy 2021;101(6) View
  16. Hsu Y, Chen Y, Lee C, Chang N. Effects of Diet Control and Telemedicine-Based Resistance Exercise Intervention on Patients with Obesity and Knee Osteoarthritis: A Randomized Control Trial. International Journal of Environmental Research and Public Health 2021;18(15):7744 View
  17. Song O, Seo K, O’Sullivan D, Park J. A Biomechanical Analysis of the Effect of Pilates Exercise on Female College Students with Knee Joint Deformity. The Asian Journal of Kinesiology 2021;23(3):20 View
  18. Holden M, Button K, Collins N, Henrotin Y, Hinman R, Larsen J, Metcalf B, Master H, Skou S, Thoma L, Wellsandt E, White D, Bennell K. Guidance for Implementing Best Practice Therapeutic Exercise for Patients With Knee and Hip Osteoarthritis: What Does the Current Evidence Base Tell Us?. Arthritis Care & Research 2021;73(12):1746 View
  19. Galavi Z, Montazeri M, Ahmadian L. Barriers and challenges of using health information technology in home care: A systematic review. The International Journal of Health Planning and Management 2022;37(5):2542 View
  20. Aminde J, Harris N, Thng C, Desbrow B. Effectiveness of self-managed home and community exercise interventions in improving physical activity, body adiposity and related health indices in adults living with HIV: a protocol for a systematic review. Systematic Reviews 2022;11(1) View
  21. Song K, Zhu S, Xiang X, Wang L, Xie S, Liu H, Yang W, He C. An evidence-based tailored eHealth patient education tool for patients with knee osteoarthritis: protocol for a randomized controlled trial. BMC Musculoskeletal Disorders 2022;23(1) View
  22. Schäfer A, Löffler-Idel I, Adelt E, Fielder C, Reinhardt A, Wilhelm N, Lochwitz A, Paelke V. Evaluation eines mHealth unterstützten Heimübungsprogramms für Menschen mit Kniearthrose (mhexos) – Bedienbarkeit, Erfahrungen von Nutzer*innen und Outcome. physioscience 2022;18(03):117 View
  23. Gardner T, Schultz R, Haskelberg H, Newby J, Wheatley J, Millard M, Faux S, Shiner C. The Effect of Adjunct Telephone Support on Adherence and Outcomes of the Reboot Online Pain Management Program: Randomized Controlled Trial. Journal of Medical Internet Research 2022;24(2):e30880 View
  24. Lang S, McLelland C, MacDonald D, Hamilton D. Do digital interventions increase adherence to home exercise rehabilitation? A systematic review of randomised controlled trials. Archives of Physiotherapy 2022;12(1) View
  25. Kamilu Sulaiman S, Wong A, Liangchi Li L, Fordjour Antwi-Afari M, Ou H, WH Tsang H. The use of mobile health technology in the management of osteoarthritis: A scoping review with scientometric analyses. International Journal of Medical Informatics 2023;170:104937 View
  26. Thompson D, Rattu S, Tower J, Egerton T, Francis J, Merolli M. Mobile app use to support therapeutic exercise for musculoskeletal pain conditions may help improve pain intensity and self-reported physical function: a systematic review. Journal of Physiotherapy 2023;69(1):23 View
  27. Babatunde O, Corp N, Shivji N, Rowlands G, Quicke J, Healey E, Protheroe J, van der Windt D. Interventions for supporting self-management in people with musculoskeletal pain, including focus on varying levels of health literacy: A systematic overview of reviews. Health Open Research 2023;5:2 View
  28. Ding J, Yang Y, Wu X, Xiao B, Ma L, Xu Y. The telehealth program of occupational therapy among older people: an up-to-date scoping review. Aging Clinical and Experimental Research 2022;35(1):23 View
  29. Edwards D, Williams J, Carrier J, Davies J. Technologies used to facilitate remote rehabilitation of adults with deconditioning, musculoskeletal conditions, stroke, or traumatic brain injury: an umbrella review. JBI Evidence Synthesis 2022;20(8):1927 View
  30. McHugh C, Kostic A, Katz J, Losina E. Effectiveness of remote exercise programs in reducing pain for patients with knee osteoarthritis: A systematic review of randomized trials. Osteoarthritis and Cartilage Open 2022;4(3):100264 View
  31. Kerckhove N, Corteval A, Eschalier A. Apport du numérique dans la prise en charge médicale des patients souffrant de douleurs chroniques. Douleur et Analgésie 2021;34(3):147 View
  32. Hirohama K, Tamura H, Hamada K, Mitsutake T, Imura T, Tanaka S, Tanaka R. Effects of Non-Face-to-Face and Noncontact Interventions on Knee Pain and Physical Activity in Older Adults With Knee Osteoarthritis: A Systematic Review and Meta-Analysis. Journal of Aging and Physical Activity 2022:1 View
  33. Aliaga-Castillo V, Horment-Lara G, Contreras-Sepúlveda F, Cruz-Montecinos C. Safety and effectiveness of telerehabilitation program in people with severe haemophilia in Chile. A qualitative study. Musculoskeletal Science and Practice 2022;60:102565 View
  34. Yang Y, Li S, Cai Y, Zhang Q, Ge P, Shang S, Han H. Effectiveness of telehealth‐based exercise interventions on pain, physical function and quality of life in patients with knee osteoarthritis: A meta‐analysis. Journal of Clinical Nursing 2023;32(11-12):2505 View
  35. Arensman R, Kloek C, Pisters M, Koppenaal T, Ostelo R, Veenhof C. Patient Perspectives on Using a Smartphone App to Support Home-Based Exercise During Physical Therapy Treatment: Qualitative Study. JMIR Human Factors 2022;9(3):e35316 View
  36. Chan A, Cohen R, Robinson K, Bhardwaj D, Gregson G, Jutai J, Millar J, Ríos Rincón A, Roshan Fekr A. Evidence and User Considerations of Home Health Monitoring for Older Adults: Scoping Review. JMIR Aging 2022;5(4):e40079 View
  37. Thiengwittayaporn S, Wattanapreechanon P, Sakon P, Peethong A, Ratisoontorn N, Charoenphandhu N, Charoensiriwath S. Development of a mobile application to improve exercise accuracy and quality of life in knee osteoarthritis patients: a randomized controlled trial. Archives of Orthopaedic and Trauma Surgery 2021;143(2):729 View
  38. Hamilton R, Williams J, Holt C. Biomechanics beyond the lab: Remote technology for osteoarthritis patient data—A scoping review. Frontiers in Rehabilitation Sciences 2022;3 View
  39. Holm P, Roos E, Grønne D, Skou S. Online and onsite supervised exercise therapy and education for individuals with knee osteoarthritis – A before and after comparison of two different care delivery models. Musculoskeletal Care 2023;21(3):878 View
  40. Evenepoel M, Van Dijck S, Meeus M, Dams L, Haenen V, Devoogdt N, Roussel N, De Groef A. Comparison of the effectiveness of eHealth self-management interventions for pain between oncological and musculoskeletal populations: a systematic review with narrative synthesis. Scandinavian Journal of Pain 2023;23(3):433 View
  41. Davergne T, Meidinger P, Dechartres A, Gossec L. The Effectiveness of Digital Apps Providing Personalized Exercise Videos: Systematic Review With Meta-Analysis. Journal of Medical Internet Research 2023;25:e45207 View
  42. Peterson G, Peolsson A. Efficacy of Neck-Specific Exercise With Internet Support Versus Neck-Specific Exercise at a Physiotherapy Clinic in Chronic Whiplash-Associated Disorders: Multicenter Randomized Controlled Noninferiority Trial. Journal of Medical Internet Research 2023;25:e43888 View
  43. Si J, Sun L, Li Z, Zhu W, Yin W, Peng L. Effectiveness of home-based exercise interventions on pain, physical function and quality of life in individuals with knee osteoarthritis: a systematic review and meta-analysis. Journal of Orthopaedic Surgery and Research 2023;18(1) View
  44. Fan I, Govil D, King M, Scholes M, Semciw A. How effective are exercises delivered digitally (requiring internet), amongst patients with hip or knee osteoarthritis? A systematic review and meta-analysis. Osteoarthritis and Cartilage 2023 View
  45. Xiang W, Wang J, Ji B, Li L, Xiang H. Effectiveness of Different Telerehabilitation Strategies on Pain and Physical Function in Patients With Knee Osteoarthritis: Systematic Review and Meta-Analysis. Journal of Medical Internet Research 2023;25:e40735 View
  46. Kaczorowski S, Donath L, Owen P, Saueressig T, Mundell N, Topp M, Samanna C, Döding R, Belavy D. Telemedicine for Patients with Musculoskeletal Pain Lacks High-Quality Evidence on Delivery Modes and Effectiveness: An Umbrella Review. Telemedicine and e-Health 2024;30(5):1221 View
  47. Bargeri S, Castellini G, Vitale J, Guida S, Banfi G, Gianola S, Pennestrì F. Effectiveness of Telemedicine for Musculoskeletal Disorders: Umbrella Review. Journal of Medical Internet Research 2024;26:e50090 View
  48. Stevenson R, Chowdhury E, Inza V, Western M, Walsh N, Jones S, Bilzon J. Development of the intelligent knee osteoarthritis lifestyle app: a person-based approach. BMC Musculoskeletal Disorders 2024;25(1) View
  49. dos Santos R, Lin J, Badwal A, Singh H, Jaglal S, Sperling C, Salbach N. Evaluations of virtual exercise programmes for adults with mobility limitations: a scoping review protocol incorporating an equity lens to inform the development of strategies to optimise participation of under-represented groups. BMJ Open 2024;14(3):e077961 View
  50. Peolsson A, Nilsing Strid E, Peterson G. Novel Internet Support for Neck-Specific Rehabilitation Improves Work-Related Outcomes to the Same Extent as Extensive Visits to a Physiotherapy Clinic in Individuals with Chronic Whiplash-Associated Disorders: A Prospective Randomised Study. Journal of Occupational Rehabilitation 2024 View
  51. Weber F, Kloek C, Stuhrmann S, Blum Y, Grüneberg C, Veenhof C. Usability and preliminary effectiveness of an app-based physical activity and education program for people with hip or knee osteoarthritis – a pilot randomized controlled trial. Arthritis Research & Therapy 2024;26(1) View

Books/Policy Documents

  1. Hinman R, Bennell K. Osteoarthritis Health Professional Training Manual. View