Symptom Checkers

Mood Monitoring, Mood Tracking, and Ambulatory Assessment Interventions in Depression and Bipolar Disorder: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Laurence Astill Wright, Georgina Shajan, Daljit Purewal, Jonathan Stone, Madiha Majid, Boliang Guo, Richard Morriss

JMIR Ment Health 2026 (Jan 07); 13:e84020

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Challenges in Developing a Patient-Reported Symptom-Based Risk Stratification System for Suspected Head and Neck Cancer: Protocol for a Qualitative Case Study

Chinasa Odo, Joanne Patterson, Nikki Rousseau, Vinidh Paleri, Rebecca Randell

JMIR Res Protoc 2025 (Nov 25); 14:e74262

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Evaluating the Accuracy of the Frysian Questionnaire for Differentiation of Musculoskeletal Complaints for Triage of Musculoskeletal Diseases: Algorithm Development and Validation Study

Tjardo Daniël Maarseveen, Floor Reimann, Ahmed al Hasan, Annemarie Schilder, Dan Zhang, Freke Wink, Lidy Hendriks, Rachel Knevel, Reinhard Bos

JMIR Med Inform 2025 (Nov 17); 13:e77345

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Patient Navigation Behavior in a Symptom-Based Self-Triage Mobile App for Direct-to-Consumer Urgent Care: Retrospective Observational Study

Tarso Augusto Duenhas Accorsi, Flavio Tocci Moreira, Anderson Aires Eduardo, Renata Albaladejo Morbeck, Karen Francine Köhler, Karine De Amicis Lima, Carlos Henrique Sartorato Pedrotti

J Med Internet Res 2025 (Nov 04); 27:e63816

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Evaluating the Efficacy of a Mobile Phone App in Enhancing Menopause Knowledge and Shared Decision-Making: Protocol for a Randomized Controlled Trial

Jana Karam, Maggie M Paul, Chrisandra Shufelt, Prajna Ravikumar, Amy M Fratianni, Sey Oloyede, Erin M Pagel, Mary S Hedges, Ekta Kapoor, Juliana M Kling, Kristin Cole, Rajeev Chaudhry, Stephanie S Faubion

JMIR Res Protoc 2025 (Oct 08); 14:e76536

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Medical Expert Knowledge Meets AI to Enhance Symptom Checker Performance for Rare Disease Identification in Fabry Disease: Mixed Methods Study

Anne Pankow, Nico Meißner-Bendzko, Jessica Kaufeld, Laura Fouquette, Fabienne Cotte, Stephen Gilbert, Ewelina Türk, Anibh Das, Christoph Terkamp, Gerhard-Rüdiger Burmester, Annette Doris Wagner

JMIR AI 2025 (Aug 28); 4:e55001

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Symptom Trajectories and Clinical Subtypes in Post–COVID-19 Condition: Systematic Review and Clustering Analysis

Mingzhi Hu, Tian Song, Zhaoyuan Gong, Qianzi Che, Jing Guo, Lin Chen, Haili Zhang, Huizhen Li, Ning Liang, Guozhen Zhao, Yanping Wang, Nannan Shi, Bin Liu

JMIR Public Health Surveill 2025 (Jul 18); 11:e72221

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Self-Determined Health App Evaluation Questionnaire Development: Mixed Methods Study

Angelika Rzepka, Kurt Edegger, Stefan Welte, Diotima Bertel, Anja Mandl, Günter Schreier

JMIR Hum Factors 2025 (Jul 01); 12:e63739

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Impact of a Symptom Checker App on Patient-Physician Interaction Among Self-Referred Walk-In Patients in the Emergency Department: Multicenter, Parallel-Group, Randomized, Controlled Trial

Malte L Schmieding, Marvin Kopka, Myrto Bolanaki, Hendrik Napierala, Maria B Altendorf, Doreen Kuschick, Sophie K Piper, Lennart Scatturin, Konrad Schmidt, Claudia Schorr, Alica Thissen, Cornelia Wäscher, Christoph Heintze, Martin Möckel, Felix Balzer, Anna Slagman

J Med Internet Res 2025 (Apr 02); 27:e64028

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Exploring Laypersons’ Experiences With a Mobile Symptom Checker App as an Interface Between eHealth Literacy, Health Literacy, and Health-Related Behavior: Qualitative Interview Study

Roland Koch, Marie-Theres Steffen, Anna-Jasmin Wetzel, Christine Preiser, Malte Klemmt, Hans-Jörg Ehni, Regina Mueller, Stefanie Joos

JMIR Form Res 2025 (Mar 21); 9:e60647

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Exploring Self-Reported Symptoms for Developing and Evaluating Digital Symptom Checkers for Polycystic Ovarian Syndrome, Endometriosis, and Uterine Fibroids: Exploratory Survey Study

Aidan P Wickham, Yella Hewings-Martin, Frederick GB Goddard, Allison K Rodgers, Adam C Cunningham, Carley Prentice, Octavia Wilks, Yusuf C Kaplan, Andrei Marhol, András Meczner, Heorhi Stsefanovich, Anna Klepchukova, Liudmila Zhaunova

JMIR Form Res 2024 (Dec 12); 8:e65469

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Unveiling Usage Patterns and Explaining Usage of Symptom Checker Apps: Explorative Longitudinal Mixed Methods Study

Anna-Jasmin Wetzel, Christine Preiser, Regina Müller, Stefanie Joos, Roland Koch, Tanja Henking, Hannah Haumann

J Med Internet Res 2024 (Dec 09); 26:e55161

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The Doctors, Their Patients, and the Symptom Checker App: Qualitative Interview Study With General Practitioners in Germany

Christine Preiser, Natalia Radionova, Eylem Ög, Roland Koch, Malte Klemmt, Regina Müller, Robert Ranisch, Stefanie Joos, Monika A Rieger

JMIR Hum Factors 2024 (Nov 18); 11:e57360

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User Views on Online Sexual Health Symptom Checker Tool: Qualitative Research

Alicia Jean King, Jade Elissa Bilardi, Janet Mary Towns, Kate Maddaford, Christopher Kincaid Fairley, Eric P F Chow, Tiffany Renee Phillips

JMIR Form Res 2024 (Nov 04); 8:e54565

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Experiences of Patients With Cancer Using Electronic Symptom Management Systems: Qualitative Systematic Review and Meta-Synthesis

Siying Zhu, Yan Dong, Yumei Li, Hong Wang, Xue Jiang, Mingen Guo, Tiantian Fan, Yalan Song, Ying Zhou, Yuan Han

J Med Internet Res 2024 (Oct 28); 26:e59061

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Triage Accuracy and the Safety of User-Initiated Symptom Assessment With an Electronic Symptom Checker in a Real-Life Setting: Instrument Validation Study

Ville Liu, Minna Kaila, Tuomas Koskela

JMIR Hum Factors 2024 (Sep 26); 11:e55099

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Comparison of Two Symptom Checkers (Ada and Symptoma) in the Emergency Department: Randomized, Crossover, Head-to-Head, Double-Blinded Study

Johannes Knitza, Ragip Hasanaj, Jonathan Beyer, Franziska Ganzer, Anna Slagman, Myrto Bolanaki, Hendrik Napierala, Malte L Schmieding, Nizam Al-Zaher, Till Orlemann, Felix Muehlensiepen, Julia Greenfield, Nicolas Vuillerme, Sebastian Kuhn, Georg Schett, Stephan Achenbach, Katharina Dechant

J Med Internet Res 2024 (Aug 20); 26:e56514

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Controlling Inputter Variability in Vignette Studies Assessing Web-Based Symptom Checkers: Evaluation of Current Practice and Recommendations for Isolated Accuracy Metrics

András Meczner, Nathan Cohen, Aleem Qureshi, Maria Reza, Shailen Sutaria, Emily Blount, Zsolt Bagyura, Tamer Malak

JMIR Form Res 2024 (May 31); 8:e49907

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Testing Two Online Symptom Checkers With Vulnerable Groups: Usability Study to Improve Cognitive Accessibility of eHealth Services

Kaisa Savolainen, Sari Kujala

JMIR Hum Factors 2024 (Mar 08); 11:e45275

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Internet Tool to Support Self-Assessment and Self-Swabbing of Sore Throat: Development and Feasibility Study

Mark Lown, Kirsten A Smith, Ingrid Muller, Catherine Woods, Emma Maund, Kirsty Rogers, Taeko Becque, Gail Hayward, Michael Moore, Paul Little, Margaret Glogowska, Alastair Hay, Beth Stuart, Efi Mantzourani, Christopher R Wilcox, Natalie Thompson, Nick A Francis

J Med Internet Res 2023 (Dec 08); 25:e39791

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