A Machine Learning Pipeline to Analyze Global Sentiment and Factors Influencing Retinoblastoma Treatment Hesitancy: Observational Infodemiology Study

Emily S Wong   ^{1, 2, 3, 4 *} , FRCOphth ;   Richard W Choy   ^{1, 2 *} , MSc ;   Esther W Tang   ¹ , MBBS ;   Yuzhou Zhang   ¹ , PhD ;   Xiu Juan Zhang   ^{1, 5} , PhD ;   Linbin Zhou   ¹ , PhD ;   Wai Kit Chu   ^{1, 4} , DPhil ;   Li Jia Chen   ^{1, 4, 6} , PhD ;   Clement C Tham   ^{1, 2, 3, 4, 6} , FRCOphth ;   Chi Pui Pang   ^{1, 4} , DPhil ;   Jason C Yam   ^{1, 2, 3, 4, 6} , MD

¹ Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China (Hong Kong)

² Hong Kong Eye Hospital, Hong Kong, China (Hong Kong)

³ Department of Ophthalmology, Hong Kong Children’s Hospital, Hong Kong, China (Hong Kong)

⁴ Hong Kong Hub of Paediatric Excellence, Chinese University of Hong Kong, Hong Kong, China (Hong Kong)

⁵ Department of Ophthalmology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China (Hong Kong)

⁶ Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China (Hong Kong)

*these authors contributed equally