The Impact of Evaluation Strategy on Sepsis Prediction Model Performance Metrics in Intensive Care Data: Retrospective Cohort Study

Dang-Khoa Do   ¹ , State Examination in Medicine ;   Patrick Rockenschaub   ² , PhD ;   Sebastian Daniel Boie   ¹ , PhD ;   Oliver Kumpf   ³ , Dr med ;   Hans-Dieter Volk   ⁴ , Dr med ;   Felix Balzer   ¹ , Dr med, Dr rer nat ;   Falk von Dincklage   ⁵ , Dr med ;   Gregor Lichtner   ^{1, 5} , Dr rer nat

¹ Institute of Medical Informatics, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

² Institute of Clinical Epidemiology, Public Health, Health Economics, Medical Statistics and Informatics, Medical University of Innsbruck, Innsbruck, Austria

³ Department of Anesthesiology and Intensive Care Medicine (CCM/CVK), Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

⁴ Institute of Medical Immunology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

⁵ Department of Anesthesia, Critical Care, Emergency and Pain Medicine, Universitätsmedizin Greifswald, Greifswald, Germany