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Published on in Vol 28 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/100426, first published .
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Magnitude and Moderators of Depressive Symptom Improvement in Digital Placebo Arms: Systematic Review and Meta-Analysis

Magnitude and Moderators of Depressive Symptom Improvement in Digital Placebo Arms: Systematic Review and Meta-Analysis

Takashi Hosono   1, 2 , PhD ;   Rinka Tsutsumi   3 ;   Yuki Niwa   1 , PhD ;   Masuo Kondoh   1, 4, 5 , PhD

1 Graduate School of Pharmaceutical Sciences, The University of Osaka, Suita, Osaka, Japan

2 Clinical Research, R&D, NS Pharma, Inc, Paramus, NJ, United States

3 Faculty of Pharmaceutical Sciences, The University of Osaka, Suita, Osaka, Japan

4 Center for Infectious Disease Education and Research (CiDER), The University of Osaka, Suita, Osaka, Japan

5 Global Center for Medical Engineering and Informatics, The University of Osaka, Suita, Osaka, Japan

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