Advancing the Use of Longitudinal Electronic Health Records: Tutorial for Uncovering Real-World Evidence in Chronic Disease Outcomes

Feiqing Huang   ^{1, 2} , PhD ;   Jue Hou   ³ , PhD ;   Ningxuan Zhou   ⁴ , MS ;   Kimberly Greco   ¹ , MA, MPH ;   Chenyu Lin   ⁵ , BS ;   Sara Morini Sweet   ⁴ , MS ;   Jun Wen   ⁴ , PhD ;   Lechen Shen   ³ , BS ;   Nicolas Gonzalez   ³ , BS ;   Sinian Zhang   ³ , BS ;   Katherine P Liao   ^{4, 6} , MD, MPH ;   Tianrun Cai   ^{2, 4, 6} , MD ;   Zongqi Xia   ⁷ , MD, PhD ;   Florence T Bourgeois   ^{2, 8, 9} , MD, MPH ;   Tianxi Cai   ^{1, 4} , ScD

¹ Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States

² Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, MA, United States

³ Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, United States

⁴ Department of Biomedical Informatics, Harvard Medical School, Boston, MA, United States

⁵ Department of Engineering, University of Toronto, Toronto, ON, Canada

⁶ Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA, United States

⁷ Department of Neurology, University of Pittsburgh, Pittsburgh, PA, United States

⁸ Computational Health Informatics Program (CHIP), Boston Children's Hospital, Boston, MA, United States

⁹ Department of Pediatrics, Harvard Medical School, Boston, MA, United States