Benefits and Harms of Digital Health Interventions Promoting Physical Activity in People With Chronic Conditions: Systematic Review and Meta-Analysis

Journals

1. Yamashita M, Kamiya K, Hamazaki N, Uchida S, Noda T, Maekawa E, Ako J. Effects of Acute Phase Intensive Physical Activity (ACTIVE-PA) Monitoring and Education for Cardiac Patients: Pilot Study of a Randomized Controlled Trial. Journal of Medical Internet Research 2023;25:e42235 View
2. Fedorchenko Y, Mahmudov K, Abenov Z, Zimba O, Yessirkepov M. Rehabilitation of patients with inflammatory rheumatic diseases and comorbidities: unmet needs. Rheumatology International 2024;44(4):583 View
3. Zangger G, Mortensen S, Tang L, Thygesen L, Skou S. Association between digital health literacy and physical activity levels among individuals with and without long-term health conditions: Data from a cross-sectional survey of 19,231 individuals. DIGITAL HEALTH 2024;10 View
4. Letton M, Trần T, Flower S, Wewege M, Wang A, Sandler C, Sen S, Arnold R. Digital Physical Activity and Exercise Interventions for People Living with Chronic Kidney Disease: A Systematic Review of Health Outcomes and Feasibility. Journal of Medical Systems 2024;48(1) View
5. Ciubean A, Popa T, Ciortea V, Dogaru G, Ungur R, Borda I, Irsay L. „Digital therapeutics” in musculoskeletal pain management: a narrative review of Gamification, Virtual Reality and Augmented Reality approaches. Balneo and PRM Research Journal 2024;15(Vol.15, no. 2):691 View
6. Brown R, Keating S, Jegatheesan D, Mayr H, Barnett A, Conley M, Webb L, Kelly J, Snoswell C, Staudacher H, Macdonald G, Burton N, Coombes J, Campbell K, Isbel N, Hickman I. Utilizing technology for diet and exercise change in complex chronic conditions across diverse environments (U-DECIDE): feasibility randomised controlled trial. BMC Health Services Research 2024;24(1) View
7. Glavas C, Scott D, Sood S, George E, Daly R, Gvozdenko E, de Courten B, Jansons P. Exploring the Feasibility of Digital Voice Assistants for Delivery of a Home-Based Exercise Intervention in Older Adults With Obesity and Type 2 Diabetes Mellitus: Randomized Controlled Trial. JMIR Aging 2024;7:e53064 View
8. Luijk A, Mortensen S, Hamborg T, Zangger G, Ahler J, Christensen J, Skou S, Tang L. The effectiveness of digital health interventions for the maintenance of physical activity following cardiac rehabilitation: A systematic review and meta-analysis. DIGITAL HEALTH 2024;10 View
9. Adnan R, Roikjaer S, Samadzadeh S, Richter C, Weinshenker B, Paul F, Skou S, Dalgas U, Asgari N. At home e-based physical exercise programs in patients with multiple sclerosis: a scoping review. Frontiers in Neurology 2024;15 View
10. Venkatasubramanian K, Appleton J, Ranalli T, Mankodiya K, Solanki D, Carreiro S. Leveraging Trauma Informed Care for Digital Health Intervention Development in Opioid Use Disorder. Journal of Medical Toxicology 2025;21(1):60 View
11. Skoglund G, Hilde G, Lunde P, Cruz Naceno V, Fromholt Olsen C, Blakstad Nilsson B. Mobile Phone App to Promote Lifestyle Change in People at Risk of Type 2 Diabetes: Feasibility 3-Arm Randomized Controlled Trial. JMIR Formative Research 2025;9:e63737 View
12. Sun C, Elia J, Prather A, Sheshadri A. Digital Lifestyle Interventions in CKD: No Better Time Than Now. Kidney International Reports 2024;9(12):3358 View
13. Lu T, Deng T, Long Y, Li J, Hu A, Hu Y, Ouyang L, Wang H, Ma J, Chen S, Hu J. Effectiveness and Feasibility of Digital Pulmonary Rehabilitation in Patients Undergoing Lung Cancer Surgery: Systematic Review and Meta-Analysis. Journal of Medical Internet Research 2024;26:e56795 View
14. Berger E, Schol C, Meertens-Gunput S, Kiers D, Gommers D, Rose L, van Mol M. Digital Health Interventions Supporting Recovery for Intensive Care Patients and Their Family Members: A Scoping Review. Mayo Clinic Proceedings: Digital Health 2025;3(1):100185 View
15. Christie R, Sadler E, Sait M, Light K, Cox C, Board M, Thomas S, Walker D, Allen-Pick M, Bradbury K, Murphy J. Digital empowerment in long-term condition management: A systematic review and narrative synthesis of the experiences and perceptions of home-based digital health coaching interventions. DIGITAL HEALTH 2024;10 View
16. Howes S, Stephenson A, Grimmett C, Argent R, Clarkson P, Khan A, Lait E, McDonough L, Tanner G, McDonough S. The effectiveness of digital tools to maintain physical activity among people with a long-term condition(s): A systematic review and meta-analysis. DIGITAL HEALTH 2024;10 View
17. Alley S, Waters K, Parker F, Peiris D, Fien S, Rebar A, Vandelanotte C. The effectiveness of digital physical activity interventions in older adults: a systematic umbrella review and meta-meta-analysis. International Journal of Behavioral Nutrition and Physical Activity 2024;21(1) View
18. Hassan L, Milton A, Sawyer C, Casson A, Torous J, Davies A, Ruiz-Yu B, Firth J. Utility of Consumer-Grade Wearable Devices for Inferring Physical and Mental Health Outcomes in Severe Mental Illness: Systematic Review. JMIR Mental Health 2025;12:e65143 View
19. Hajdú S, Bøgard H, Aagaard T, Roikjær S, Simonÿ C, Dalhoff A, Houlind K, Luijk A, Ulriksen I, Jensen L, Skou S, Tang L, Callegari S. Supervised exercise-based rehabilitation for people with intermittent claudication–Study protocol for a Danish implementation process (StRiDE). PLOS ONE 2025;20(1):e0315577 View
20. Chang J, Wu W, Qian P, Lu Z, He X, Wang F, Zhang T. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue. Frontiers in Cell and Developmental Biology 2025;12 View
21. Thurston C, Humphries S, Bezuidenhout L, Johansson S, Holmlund L, von Koch L, English C, Moulaee Conradsson D. Mobile health delivered physical activity after mild stroke or transient ischemic attack: Is it feasible and acceptable?. International Journal of Stroke 2025;20(7):801 View
22. Li C, Zhu C, Song K, Xiang X, Wang X, Hu J, Li Z, Deng Y, Jiang D, Guo L, Ren T, Zhu L, Ai H, Zhang S, Liu Z, Yang Y, Zhu S, He C. An evidence-based tailored eHealth patient education tool for patients with knee osteoarthritis: A randomized controlled trial. DIGITAL HEALTH 2025;11 View
23. Glock H, Björk Javanshiri A, Borgström Bolmsjö B, Jakobsson U, Milos Nymberg V, Wolff M, Calling S. Promoting lifestyle change through text messages to patients with hypertension: A randomized controlled trial in Swedish primary care. Preventive Medicine Reports 2025;51:103009 View
24. Wlazło M, Szlacheta P, Grajek M, Staśkiewicz-Bartecka W, Rozmiarek M, Malchrowicz-Mośko E, Korzonek-Szlacheta I. The Impact of Kinesiophobia on Physical Activity and Quality of Life in Patients with Chronic Diseases: A Systematic Literature Review. Applied Sciences 2025;15(4):2086 View
25. Koczwara B, Lee J, Naghavi N, Bareham M, Wallen M, Piller N, Chan R. “Do I buy my children shoes, or do I get a compression garment for my lymphoedema?” Australian stakeholder perspectives on cancer-related lymphoedema care. Journal of Cancer Survivorship 2025 View
26. Vázquez-García J, Hernández-Zenteno R, Arroyo-Hernández M, Elizondo-Ríos A, Casillas-Suárez C, Cortés-Telles A, Pérez-Padilla J, Sandoval-Gutiérrez J, Vázquez-Cortés J, Thirión-Romero I, Monraz-Pérez S, Robles-Hernández R, Rodríguez-Vega M, Mayorga-Butrón J. Guía de Práctica Clínica Mexicana de EPOC 2025. NCT Neumología y Cirugía de Tórax 2025;84(S1):S8 View
27. Akgül H, Birtane M, Tonga E. Effects of a Digitally Supported Physical Activity Intervention in Knee Osteoarthritis: A Pilot Randomized Controlled Trial. Musculoskeletal Care 2025;23(2) View
28. Wang Y, Zhu T, Zhou T, Wu B, Tan W, Ma K, Yao Z, Wang J, Li S, Qin F, Xu Y, Tan L, Liu J, Wang J. Hyper-DREAM, a Multimodal Digital Transformation Hypertension Management Platform Integrating Large Language Model and Digital Phenotyping: Multicenter Development and Initial Validation Study. Journal of Medical Systems 2025;49(1) View
29. Iwakura M, Ozeki C, Jung S, Yamazaki T, Miki T, Nohara M, Nomura K. An umbrella review of efficacy of digital health interventions for workers. npj Digital Medicine 2025;8(1) View
30. Long J, You J, Yang Y. Effect of Digital Exercise Therapy on the Pain and Physical Function of Patients With Osteoarthritis: Systematic Review and Meta-Analysis. Journal of Medical Internet Research 2025;27:e66037 View
31. Lakhan S. Cognitive Resilience for the Prevention of Mild Cognitive Impairment in Subjective Cognitive Decline: A Monte Carlo Simulation of a Digital Therapeutic Targeting Dementia Risk Factors. Cureus 2025 View
32. Goveia J, Vargas L, Freitas Júnior M, Pedroso B, Carmo G. Atividade Física e estrutura RE-AIM: uma análise bibliométrica da produção científica na Web Of Science. Revista Brasileira de Atividade Física & Saúde 2025;30:1 View
33. Zangger G, Grønne D, Tang L, Thygesen L, Roos E, Skou S. Digital Readiness Among 3555 Individuals With Hip or Knee Osteoarthritis Initiating a Supervised Education and Exercise Therapy Programme: A Cross‐Sectional Study. Musculoskeletal Care 2025;23(2) View
34. Alòs F, Romaguera M, Cos Claramunt F, Orfila F, Aldon Mínguez D, Puig-Ribera A. Actividad física en la era digital: retos y oportunidades para la atención primaria. Atención Primaria 2025;57(12):103301 View
35. Wilkins B, Mansoubi M, Veerapen J, Dawes H, Waller B. Evaluation and Cost‐Consequence Analysis of a Community‐Based Digital Exercise Intervention for People With Musculoskeletal Conditions. Musculoskeletal Care 2025;23(2) View
36. Li P, Cheung M, Chow K, Leung M, Lim L, Lui J, Luk A, Manski-Nankervis J, Seidu S, Tandon N, Liew A, Lin P, Pang F, Tian N, Ueki K, Wong M, Zoungas S, Loo K, Chung K, Hung V, Vu H, Lee M, Sung J, Szeto C, Tsang M, Wong S, Ng J, Chung H, Tang S, Kung K, Lui S, Chao D, Cyzewski C, Green T, Chan J. Kidney Disease: Improving Global Outcomes Summit Recommendations on Implementation of Diabetes Management in CKD: From Primary to Data-Driven Collaborative Care. Kidney International Reports 2025;10(8):2551 View
37. Nøhr N, Zangger G, Buch Dalum F, Skou S, Juhl C, Bricca A. Effect of Components and Delivery Modes of Digital Health Interventions Targeting Physical Activity in People With a Chronic Condition or Multimorbidity: A Systematic Review and Component Network Meta-Analysis of Randomized Controlled Trials. Journal of Physical Activity and Health 2025;22(10):1209 View
38. Cheng W, Miao M, Jiao L, Liu X, Alipour J. How digital health literacy shapes health: Mediating role of physical activity and heterogeneity in China. PLOS One 2025;20(7):e0328101 View
39. Kjeldsen T, Dalgas U, Skou S, Tønning L, Ingwersen K, Birch S, Holm P, Garval M, Varnum C, Callesen J, Foldager F, Bibby B, Mechlenburg I. Booster sessions for maintaining the effect of neuromuscular exercise and progressive resistance training in hip osteoarthritis: 12-month follow-up from a multicenter cluster-randomized controlled trial. Osteoarthritis and Cartilage 2025;33(11):1393 View
40. Child C, Paetznick M, Turner A, Ho L, Brown M. Pulse Oximetry Self-Monitoring Enhances Perceived Safety and Autonomy During Home Exercise in Adults With Idiopathic Pulmonary Fibrosis. Topics in Geriatric Rehabilitation 2025;41(3):184 View
41. Hayvon J. Media as Confounder in Social Justice and Social Stratification: A Freirean Framework for Critical Media Studies. Howard Journal of Communications 2025;36(4):438 View
42. Xue H, Zhang L, Shi Y, Zhang H, Zhang C, Liu Y, Tan W, Liu Y. The effectiveness of digital health intervention on glycemic control and physical activity in patients with type 2 diabetes: a systematic review and meta-analysis. Frontiers in Digital Health 2025;7 View
43. Brown R, Simmich J, Cuthbert R, Ross M, Molina-Garcia P, Russell T. Safety of videoconferencing for physical rehabilitation and exercise: A systematic review and meta-analysis. Clinical Rehabilitation 2025;39(9):1219 View
44. Liu X, Wang W. Comment on: Effectiveness of digital health interventions for telemedicine/telehealth for managing blood pressure in adults: a systematic review and meta-analysis. Hypertension Research 2025;48(10):2758 View
45. Leese C, Abraham K, van de Konijnenburg C, Al-Zubaidi H. The effectiveness and acceptability of digital health interventions as tools to promote physical activity in primary care: an update scoping review. Primary Health Care Research & Development 2025;26 View
46. Nißen M, Harperink S, Joshi P, Bischof A, Schachner T, Lukic Y, Schneider F, Santhanam P, v Wangenheim F, Ollier J, Kowatsch T. Leveraging Influencers to Reach and Engage Vulnerable Individuals With a Digital Health Intervention: Quasi-Experimental Field Study. Journal of Medical Internet Research 2025;27:e67174 View
47. Xia Y, Zhang Y, Su D. Knowledge, attitudes, and practices of COPD patients regarding acute exacerbations of COPD. Frontiers in Medicine 2025;12 View
48. Liu Y, Qin Y, Chen Q, Liu Y, Wang Z, Jia A, Liu M, Ji N, Zhang Z, Shao R, Bai Y. Effectiveness of mobile health interventions on physical activity management in adults with hypertension: A systematic review and meta-analysis. International Journal of Nursing Studies 2025;172:105225 View
49. 郑 宇. The Influencing Factors of the Concept of Digital Health Accessibility on the Quality of Nursing Services and Prospect. Advances in Clinical Medicine 2025;15(09):1716 View
50. Ask S, Wennerberg C, Kaldo V, Hellström A. Expectations, experiences and effects for couples participating in a digital sexual rehabilitation programme after radical prostatectomy: a feasibility study in Sweden. BMJ Connections Oncology 2025;2(1):e000010 View
51. Martinsen L, Østerås N, Moseng T, Tveter A. App-based exercise intervention versus supervised exercise therapy for patients with hip or knee osteoarthritis—the randomised noninferiority DigiOA trial. EULAR Rheumatology Open 2025;1(3):295 View
52. Park G, Lee H, Lee M, Khang A. Impact of Mobile App-Based Self-Monitoring Engagement on Self-Care Self-Efficacy, Health Behaviors, and Hemoglobin A1c Among Patients With Type 2 Diabetes Mellitus: A Secondary Analysis of a Randomized Controlled Trial. Western Journal of Nursing Research 2025;47(12):1180 View
53. Pavic T, Nadarajah K, Somat A, Cabagno G, Terrade F. Endometriosis Support and Development of Digital Technology–Based Interventions: Systematic Review. JMIR Human Factors 2025;12:e71859 View
54. Yioukka M, Dinas P, Ntoumas I, Karatzaferi C, Sakkas G. Effects of smartphone-based-interventions on health-related quality of life of adults with type 2 diabetes mellitus. A systematic review and meta-analysis. Clinical Epidemiology and Global Health 2025;36:102229 View
55. Raquib N, Alshibane M, Awad Elkarim N, Osman A, Ahmed Y, Elhaj F, Abbas I. Digital Health and Telemedicine Interventions for Hypertension Management in Adults: A Systematic Review. Cureus 2025 View
56. Ni X, Xue H, Fan L, Li M, Yang J, Du W. Network meta analysis of contributions by different healthcare practitioners in digital self care for hypertension. npj Digital Medicine 2025;8(1) View
57. De Luca V, Virgolesi M, Cuomo A, Lemmo D, Perillo M, Canfora F, Aprano S, Mezza F, Vetrani C, Freda M, Adamo D, Rea T, Mercurio L, Attaianese E, Menditto E, Colao A, Iaccarino G, Illario M. Digital interventions addressing the unmet needs of older adults with multimorbidity: a mixed-methods persona design approach. Frontiers in Public Health 2025;13 View
58. Pozza M, Navarin N, Sakkalis V, Gabrielli S. Artificial Intelligence Methods and Digital Intervention Strategies for Predicting and Managing Chronic Obstructive Pulmonary Disease Exacerbations: An Umbrella Review. Healthcare 2025;13(23):3037 View
59. Liu S, Gao G, Wang X, Yu J. Influence of an internet-based proactive follow-up management model on the prognosis of nonalcoholic fatty liver disease. World Journal of Gastroenterology 2025;31(44) View

Books/Policy Documents

1. Chakraborty T, Sharada V, Gohain D. AI Technologies and Advancements for Psychological Well-Being and Healthcare. View