This paper is in the following e-collection/theme issue:

Viewpoints and Perspectives (619) New Methods (1134) Tools, Programs and Algorithms (376)

Published on in Vol 25 (2023)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/43484, first published .
Data Challenges for Externally Controlled Trials: Viewpoint

Data Challenges for Externally Controlled Trials: Viewpoint

Data Challenges for Externally Controlled Trials: Viewpoint

Authors of this article:

Russanthy Ruthiran Velummailum1 Author Orcid Image ;   Chelsea McKibbon1 Author Orcid Image ;   Darren R Brenner2 Author Orcid Image ;   Elizabeth Ann Stringer3 Author Orcid Image ;   Leeland Ekstrom3 Author Orcid Image ;   Louis Dron1 Author Orcid Image
Article Authors Cited by (10) Tweetations (2) Metrics

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  2. Struebing A, McKibbon C, Ruan H, Mackay E, Dennis N, Velummailum R, He P, Tanaka Y, Xiong Y, Springford A, Rosenlund M. Augmenting external control arms using Bayesian borrowing: a case study in first-line non-small cell lung cancer. Journal of Comparative Effectiveness Research 2024;13(5) View
  3. Farah E, Kenney M, Warkentin M, Cheung W, Brenner D. Examining external control arms in oncology: A scoping review of applications to date. Cancer Medicine 2024;13(13) View
  4. Janda G, Jeffery M, Ramachandran R, Ross J, Wallach J. Feasibility of using real-world data to emulate substance use disorder clinical trials: a cross-sectional study. BMC Medical Research Methodology 2024;24(1) View
  5. Rudra Gupta T, Schwartz D, Saha R, Wen P, Rahman R, Trippa L. Informative censoring in externally controlled clinical trials: a potential source of bias. ESMO Open 2025;10(1):104094 View
  6. Carlsson L, Peltonen M, Jacobson P, Andersson-Assarsson J, Svensson P, Taube M, Karlsson C, Ahlin S, Kristensson F, Perkins R, Arnetorp I, Carlsson A, Admeus L, Langegård E, Carlsson B, Sjöholm K. Possible selection bias in register-based obesity studies. European Journal of Epidemiology 2025;40(7):759 View
  7. Declerck J, Lee J, Sen A, Palmeri A, Oostenbrink R, Giannuzzi V, Woodworth S, Malik S, Mahler F, Aurich B, Leary R, Kalra D, Straub V. The Potential to Leverage Real-World Data for Pediatric Clinical Trials: A Proof-of-Concept Study. Journal of Medical Internet Research 2025;27:e72573 View
  8. Litman H, Sheffield K, Pugach O, Shan M, Lakin P, Cui Z, Curtis S, Johnston J, Harrold L. Applying Bias Correction Methods to Build Hybrid Controls Using Real‐World Patients for a Phase IIb Randomized Controlled Trial of Baricitinib for Rheumatoid Arthritis. Pharmaceutical Statistics 2025;24(4) View
  9. Liu J, Yao M, Wang M, Jie W, Liu Y, Luo X, Huan J, Deng K, Deng K, Zou K, Zhang Y, Li L, Sun X. Design, Conduct, and Analysis of Externally Controlled Trials. JAMA Network Open 2025;8(9):e2530277 View
  10. Fujita K, Kinoshita F, Kuroda Y, Sugimoto T, Yamashita M, Sakurai H, Yamashiro D, Shimizu K, Matsumoto N, Uchida K, Yokoyama Y, Onoyama A, Kobayashi Y, Suzuki H, Fujiwara Y, Arai H, Sakurai T. Feasibility and effectiveness of a handbook-based multidomain lifestyle intervention for older adults with mild cognitive impairment: A quasi-experimental design with propensity score matching. Journal of Alzheimer’s Disease 2025;107(4):1768 View