Published on in Vol 22, No 7 (2020): July

Preprints (earlier versions) of this paper are available at, first published .
The Acceptability and Usability of Digital Health Interventions for Adults With Depression, Anxiety, and Somatoform Disorders: Qualitative Systematic Review and Meta-Synthesis

The Acceptability and Usability of Digital Health Interventions for Adults With Depression, Anxiety, and Somatoform Disorders: Qualitative Systematic Review and Meta-Synthesis

The Acceptability and Usability of Digital Health Interventions for Adults With Depression, Anxiety, and Somatoform Disorders: Qualitative Systematic Review and Meta-Synthesis


  1. Emerson M, Harsh Caspari J, Notice M, Watanabe-Galloway S, Dinkel D, Kabayundo J. Mental health mobile app use: Considerations for serving underserved patients in integrated primary care settings. General Hospital Psychiatry 2021;69:67 View
  2. Morriss R, Kaylor-Hughes C, Rawsthorne M, Coulson N, Simpson S, Guo B, James M, Lathe J, Moran P, Tata L, Williams L. A Direct-to-Public Peer Support Program (Big White Wall) Versus Web-Based Information to Aid the Self-management of Depression and Anxiety: Results and Challenges of an Automated Randomized Controlled Trial. Journal of Medical Internet Research 2021;23(4):e23487 View
  3. Mitchell L, Joshi U, Patel V, Lu C, Naslund J. Economic Evaluations of Internet-Based Psychological Interventions for Anxiety Disorders and Depression: A Systematic Review. Journal of Affective Disorders 2021;284:157 View
  4. Buckman J, Saunders R, Leibowitz J, Minton R. The barriers, benefits and training needs of clinicians delivering psychological therapy via video. Behavioural and Cognitive Psychotherapy 2021;49(6):696 View
  5. Van Der Walt M, Keddy K. The Tuberculosis-Depression Syndemic and Evolution of Pharmaceutical Therapeutics: From Ancient Times to the Future. Frontiers in Psychiatry 2021;12 View
  6. Lindegaard T, Kashoush F, Holm S, Halaj A, Berg M, Andersson G. Experiences of internet-based cognitive behavioural therapy for depression and anxiety among Arabic-speaking individuals in Sweden: a qualitative study. BMC Psychiatry 2021;21(1) View
  7. Zidaru T, Morrow E, Stockley R. Ensuring patient and public involvement in the transition to AI‐assisted mental health care: A systematic scoping review and agenda for design justice. Health Expectations 2021;24(4):1072 View
  8. Dauber S, West A, Hammond C, Cohen I, Thrul J. Postpartum heavy episodic drinking: A survey to inform development of a text messaging intervention. Drug and Alcohol Review 2022;41(1):182 View
  9. Finazzi E, MacBeth A. Service users experience of psychological interventions in primary care settings: A qualitative meta‐synthesis. Clinical Psychology & Psychotherapy 2022;29(2):400 View
  10. Toonders S, Poolman E, Nieboer M, Pisters M, Veenhof C. Healthcare professionals' perspectives on a blended care program in primary care; A qualitative study. Internet Interventions 2021;26:100440 View
  11. Taylor M, Thomas E, Vitangcol K, Marx W, Campbell K, Caffery L, Haydon H, Smith A, Kelly J. Digital health experiences reported in chronic disease management: An umbrella review of qualitative studies. Journal of Telemedicine and Telecare 2022;28(10):705 View
  12. White K, Dawe-Lane E, Siddi S, Lamers F, Simblett S, Riquelme Alacid G, Ivan A, Myin-Germeys I, Haro J, Oetzmann C, Popat P, Rintala A, Rubio-Abadal E, Wykes T, Henderson C, Hotopf M, Matcham F. Understanding the Subjective Experience of Long-term Remote Measurement Technology Use for Symptom Tracking in People With Depression: Multisite Longitudinal Qualitative Analysis. JMIR Human Factors 2023;10:e39479 View
  13. Bielinski L, Bur O, Wälchli G, Suter J, Walsh N, Kley M, Krieger T, Berger T. Two sides of the same coin? Patient and therapist experiences with a transdiagnostic blended intervention focusing on emotion regulation. Internet Interventions 2022;30:100586 View
  14. Nicolaisen Sidén F, Spak F. Secondary psychiatric care patients’ experiences of internet CBT for insomnia – a qualitative study. BMC Psychology 2022;10(1) View
  15. Beahm J, Landry C, McCall H, Carleton R, Hadjistavropoulos H. Understanding and Addressing Occupational Stressors in Internet-Delivered Therapy for Public Safety Personnel: A Qualitative Analysis. International Journal of Environmental Research and Public Health 2022;19(8):4744 View
  16. Whitehead L, Talevski J, Fatehi F, Beauchamp A. Barriers to and Facilitators of Digital Health Among Culturally and Linguistically Diverse Populations: Qualitative Systematic Review. Journal of Medical Internet Research 2023;25:e42719 View
  17. Bevens W, Reece J, Jelinek P, Weiland T, Nag N, Simpson-Yap S, Gray K, Jelinek G, Neate S. The feasibility of an online educational lifestyle program for people with multiple sclerosis: A qualitative analysis of participant semi-structured interviews. DIGITAL HEALTH 2022;8:205520762211237 View
  18. Durán L, Almeida A, Lopes A, Figueiredo-Braga M. Impact of a Digital Intervention for Literacy in Depression among Portuguese University Students: A Randomized Controlled Trial. Healthcare 2022;10(1):165 View
  19. Harith S, Backhaus I, Mohbin N, Ngo H, Khoo S. Effectiveness of digital mental health interventions for university students: an umbrella review. PeerJ 2022;10:e13111 View
  20. Saleem M, Kühne L, De Santis K, Christianson L, Brand T, Busse H. Understanding Engagement Strategies in Digital Interventions for Mental Health Promotion: Scoping Review. JMIR Mental Health 2021;8(12):e30000 View
  21. Chapman N, Browning M, Baghurst D, Hotopf M, Willis D, Haylock S, Zakaria S, Speechley J, Withey J, Brooks E, Chan F, Pappa S, Geddes J, Insole L, Mohammed Z, Kessler D, Jones P, Mansoori P. Setting national research priorities for difficult-to-treat depression in the UK between 2021-2026. Journal of Global Health 2022;12 View
  22. Berg I, Hovne V, Carlbring P, Bernhard-Oettel C, Oscarsson M, Mechler J, Lindqvist K, Topooco N, Andersson G, Philips B. “Good job!”: Therapists' encouragement, affirmation, and personal address in internet-based cognitive behavior therapy for adolescents with depression. Internet Interventions 2022;30:100592 View
  23. Philippe T, Sikder N, Jackson A, Koblanski M, Liow E, Pilarinos A, Vasarhelyi K. Digital Health Interventions for Delivery of Mental Health Care: Systematic and Comprehensive Meta-Review. JMIR Mental Health 2022;9(5):e35159 View
  24. Seery C, Wrigley M, O'Riordan F, Kilbride K, Bramham J. What adults with ADHD want to know: A Delphi consensus study on the psychoeducational needs of experts by experience. Health Expectations 2022;25(5):2593 View
  25. Madhusudhan D, Watts S, Lord D, Ding F, Lawrence D, Sheldon A, Leonard J, Bravata D. Employer-Sponsored Health Centers Provide Access to Integrated Care via a Hybrid of Virtual and In-Person Visits. Telemedicine Reports 2021;2(1):247 View
  26. Lindegaard T, Wasteson E, Demetry Y, Andersson G, Richards D, Shahnavaz S. Investigating the potential of a novel internet-based cognitive behavioural intervention for Dari and Farsi speaking refugee youth: A feasibility study. Internet Interventions 2022;28:100533 View
  27. Karthan M, Martin R, Holl F, Swoboda W, Kestler H, Pryss R, Schobel J. Enhancing mHealth data collection applications with sensing capabilities. Frontiers in Public Health 2022;10 View
  28. Ahuvia I, Sung J, Dobias M, Nelson B, Richmond L, London B, Schleider J. College student interest in teletherapy and self-guided mental health supports during the COVID-19 pandemic. Journal of American College Health 2024;72(3):940 View
  29. MacKean M, Lecchi T, Mortimer R, Midgley N. ‘I’ve started my journey to coping better’: exploring adolescents’ journeys through an internet-based psychodynamic therapy (I-PDT) for depression. Journal of Child Psychotherapy 2023;49(3):432 View
  30. Matcham F, Carr E, White K, Leightley D, Lamers F, Siddi S, Annas P, de Girolamo G, Haro J, Horsfall M, Ivan A, Lavelle G, Li Q, Lombardini F, Mohr D, Narayan V, Penninx B, Oetzmann C, Coromina M, Simblett S, Weyer J, Wykes T, Zorbas S, Brasen J, Myin-Germeys I, Conde P, Dobson R, Folarin A, Ranjan Y, Rashid Z, Cummins N, Dineley J, Vairavan S, Hotopf M. Predictors of engagement with remote sensing technologies for symptom measurement in Major Depressive Disorder. Journal of Affective Disorders 2022;310:106 View
  31. Lau Y, Wong S, Cheng L, Lau S. Exploring experiences and needs of perinatal women in digital healthcare: A meta-ethnography of qualitative evidence. International Journal of Medical Informatics 2023;169:104929 View
  32. Ditton E, Knott B, Hodyl N, Horton G, Walker F, Nilsson M. Medical Student Experiences of Engaging in a Psychological Flexibility Skill Training App for Burnout and Well-being: Pilot Feasibility Study. JMIR Formative Research 2023;7:e43263 View
  33. Hafner J, Schönfeld S, Tokgöz P, Choroschun K, Schlubach A, Dockweiler C. Digital Health Interventions in Depression Care—A Survey on Acceptance from the Perspective of Patients, Their Relatives and Health Professionals. Healthcare 2022;10(10):2019 View
  34. Beahm J, McCall H, Carleton R, Titov N, Dear B, Hadjistavropoulos H. Insights into internet-delivered cognitive behavioural therapy for public safety personnel: Exploration of client experiences during and after treatment. Internet Interventions 2021;26:100481 View
  35. Sayar H, Vøllestad J, Nordgreen T. What I missed from my online therapist: A survey-based qualitative investigation of patient experiences of therapist contact in guided internet interventions. Frontiers in Psychology 2023;14 View
  36. Bisby M, Karin E, Hathway T, Scott A, Heriseanu A, Dudeney J, Fisher A, Gandy M, Cross S, Staples L, Titov N, Dear B. A meta-analytic review of randomized clinical trials of online treatments for anxiety: Inclusion/exclusion criteria, uptake, adherence, dropout, and clinical outcomes. Journal of Anxiety Disorders 2022;92:102638 View
  37. Murphy M, Newby J, Butow P, Joubert A, Kirsten L, Shaw J, Shepherd H, Andrews G. A mixed methods pilot and feasibility open trial of internet-delivered cognitive behaviour therapy (iCanADAPT Advanced) for people with advanced cancer with depression and/or anxiety. Internet Interventions 2021;26:100449 View
  38. Moghimi E, Knyahnytska Y, Omrani M, Nikjoo N, Stephenson C, Layzell G, Frederic Simpson A, Alavi N. Benefits of Digital Mental Health Care Interventions for Correctional Workers and Other Public Safety Personnel: A Narrative Review. Frontiers in Psychiatry 2022;13 View
  39. Ramos G, Montoya A, Hammons H, Smith D, Chavira D, Rith-Najarian L. Digital Intervention Barriers Scale–7 (DIBS-7): Development, Evaluation, and Preliminary Validation. JMIR Formative Research 2023;7:e40509 View
  40. Shkel J, Green G, Le S, Kaveladze B, Marcotte V, Rushton K, Nguyen T, Schueller S. Understanding Users’ Experiences of a Novel Web-Based Cognitive Behavioral Therapy Platform for Depression and Anxiety: Qualitative Interviews From Pilot Trial Participants. JMIR Formative Research 2023;7:e46062 View
  41. Wilson H, Hayward P, Donkin L. Will they or won't they? Understanding New Zealand adults' attitudes towards using digital interventions. Frontiers in Digital Health 2023;5 View
  42. Lau Y, Chew H, Ang W, Ang W, Yeo C, Lim G, Wong S, Lau S, Cheng L. Effects of digital health interventions on the psychological outcomes of perinatal women: umbrella review of systematic reviews and meta-analyses. Health Psychology Review 2023:1 View
  43. Drews‐Windeck E, Greenwood K, Cavanagh K. A systematic review and meta‐analysis of digital interventions targeted at individuals with borderline personality disorder (BPD), emotionally unstable personality disorder (EUPD), and related symptoms. Journal of Clinical Psychology 2023;79(9):2155 View
  44. Emerson M, Dinkel D, Watanabe-Galloway S, Torous J, Johnson D. Adaptation of digital navigation training for integrated behavioral health providers: Interview and survey study. Translational Behavioral Medicine 2023;13(8):612 View
  45. Wong A, Bayuo J, Wong F, Chow K, Wong S, Lau A. The Synergistic Effect of Nurse Proactive Phone Calls With an mHealth App Program on Sustaining App Usage: 3-Arm Randomized Controlled Trial. Journal of Medical Internet Research 2023;25:e43678 View
  46. von der Groeben S, Czaplicki A, Hegerl U, Reich H. Telemedicine during the COVID-19 pandemic in Germany: Results from three nationally representative surveys on use, attitudes and barriers among adults affected by depression. Internet Interventions 2023;32:100622 View
  47. Forman-Hoffman V, Kvedar J, Ranta K. Potential Benefits of Remote Continuous Care for Depression. International Journal of Digital Health 2021;1(1):15 View
  48. Karlsson-Good M, Kaldo V, Lundberg L, Kraepelien M, Anthony S, Holländare F. Increasing the accessibility to internet-based cognitive behavioural therapy for depression: A single-blind randomized controlled trial of condensed versus full-text versions. Internet Interventions 2023;34:100678 View
  49. Lukka L, Salonen A, Vesterinen M, Karhulahti V, Palva S, Palva J. The qualities of patients interested in using a game-based digital mental health intervention for depression: a sequential mixed methods study. BMC Digital Health 2023;1(1) View
  50. Pokowitz E, Stiles B, Thomas R, Bullard K, Ludwig K, Gleeson J, Alvarez-Jimenez M, Perkins D, Penn D. User experiences of an American-adapted moderated online social media platform for first-episode psychosis: Qualitative analysis. DIGITAL HEALTH 2023;9:205520762311767 View
  51. Rajna P. Pszichoszomatikus tünetek és betegségek: a medicina vakfoltja. Orvosi Hetilap 2021;162(7):252 View
  52. Berg M, Klemetz H, Lindegaard T, Andersson G. Self-esteem in new light: a qualitative study of experiences of internet-based cognitive behaviour therapy for low self-esteem in adolescents. BMC Psychiatry 2023;23(1) View
  53. Ollier J, Suryapalli P, Fleisch E, Wangenheim F, Mair J, Salamanca-Sanabria A, Kowatsch T. Can digital health researchers make a difference during the pandemic? Results of the single-arm, chatbot-led Elena+: Care for COVID-19 interventional study. Frontiers in Public Health 2023;11 View
  54. Jackson H, Calear A, Batterham P, Ohan J, Farmer G, Farrer L. Skill Enactment and Knowledge Acquisition in Digital Cognitive Behavioral Therapy for Depression and Anxiety: Systematic Review of Randomized Controlled Trials. Journal of Medical Internet Research 2023;25:e44673 View
  55. Seaton N, Moss-Morris R, Hulme K, Macaulay H, Hudson J. A cognitive–behavioural therapy programme for managing depression and anxiety in long-term physical health conditions: mixed-methods real-world evaluation of the COMPASS programme. BJPsych Open 2023;9(5) View
  56. Singleton A, Raeside R, Hyun K, Hayes M, Sherman K, Elder E, Redfern J, Partridge S. A National Health and Wellness SMS Text Message Program for Breast Cancer Survivors During COVID-19 (EMPOWER-SMS COVID-19): Mixed Methods Evaluation Using the RE-AIM Framework. Journal of Medical Internet Research 2023;25:e45164 View
  57. Creber A, Leo D, Buckley B, Chowdhury M, Harrison S, Isanejad M, Lane D. Use of telemonitoring in patient self-management of chronic disease: a qualitative meta-synthesis. BMC Cardiovascular Disorders 2023;23(1) View
  58. Cederberg M, Barenfeld E, Ali L, Ekman I, Goulding A, Fors A. A lowered threshold to partnerships: a mixed methods process evaluation of participants’ experiences of a person-centred eHealth intervention. BMC Health Services Research 2023;23(1) View
  59. Patel P, Brown S, Guo B, Holmes E, Iyadurai L, Kingslake J, Highfield J, Morriss R. Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences. JMIR Formative Research 2024;8:e47458 View
  60. Heidari-Soureshjani R, Daneshvar M, Mohammadi T, Negarandeh R, Sayadi L. The effectiveness of telehealth interventions for people with multiple sclerosis: A systematic review and meta-analysis protocol. DIGITAL HEALTH 2023;9 View
  61. Deisenhofer A, Barkham M, Beierl E, Schwartz B, Aafjes-van Doorn K, Beevers C, Berwian I, Blackwell S, Bockting C, Brakemeier E, Brown G, Buckman J, Castonguay L, Cusack C, Dalgleish T, de Jong K, Delgadillo J, DeRubeis R, Driessen E, Ehrenreich-May J, Fisher A, Fried E, Fritz J, Furukawa T, Gillan C, Gómez Penedo J, Hitchcock P, Hofmann S, Hollon S, Jacobson N, Karlin D, Lee C, Levinson C, Lorenzo-Luaces L, McDanal R, Moggia D, Ng M, Norris L, Patel V, Piccirillo M, Pilling S, Rubel J, Salazar-de-Pablo G, Saunders R, Schleider J, Schnurr P, Schueller S, Siegle G, Uher R, Watkins E, Webb C, Wiltsey Stirman S, Wynants L, Youn S, Zilcha-Mano S, Lutz W, Cohen Z. Implementing precision methods in personalizing psychological therapies: Barriers and possible ways forward. Behaviour Research and Therapy 2024;172:104443 View
  62. Ren L, Chen M, Jiang H, Wang Y, Xia L, Dong C. Perceptions of adult patients with cancer towards telemedicine: A qualitative meta-synthesis. Asia-Pacific Journal of Oncology Nursing 2024;11(2):100360 View
  63. Andersson G. Innovating CBT and Answering New Questions: the Role of Internet-Delivered CBT. International Journal of Cognitive Therapy 2023 View
  64. Valla L, Haga S, Garthus-Niegel S, Drozd F. Dropout or Drop-In Experiences in an Internet-Delivered Intervention to Prevent Depression and Enhance Subjective Well-Being During the Perinatal Period: Qualitative Study. JMIR Pediatrics and Parenting 2023;6:e46982 View
  65. Li Q, Piaseu N, Phumonsakul S, Thadakant S. Effects of a Comprehensive Dietary Intervention Program, Promoting Nutrition Literacy, Eating Behavior, Dietary Quality, and Gestational Weight Gain in Chinese Urban Women with Normal Body Mass Index during Pregnancy. Nutrients 2024;16(2):217 View
  66. Rimmer R, Woodham R, Cahill S, Fu C. Acceptability of home-based transcranial direct current stimulation (tDCS) in major depression: a qualitative analysis of individual experiences. Mental Health Review Journal 2024;29(1):79 View
  67. Posselt J, Baumann E, Dierks M. A qualitative interview study of patients' attitudes towards and intention to use digital interventions for depressive disorders on prescription. Frontiers in Digital Health 2024;6 View
  68. Ncheka J, Menon J, Davies E, Paul R, Mwaba S, Mudenda J, Wharrad H, Tak H, Glazebrook C. Implementing internet-based cognitive behavioural therapy (moodgym) for African students with symptoms of low mood during the COVID-19 pandemic: a qualitative feasibilty study. BMC Psychiatry 2024;24(1) View
  69. Malgaroli M, Hull T, Calderon A, Simon N. Linguistic markers of anxiety and depression in Somatic Symptom and Related Disorders: Observational study of a digital intervention. Journal of Affective Disorders 2024;352:133 View
  70. Thapar S, Nguyen M, Khan B, Fanaieyan R, Kishimoto V, Liu R, Bolea-Alamañac B, Leon-Carlyle M, O’Riordan A, Keresteci M, Bhattacharyya O. Patient and Therapist Perceptions of a Publicly Funded Internet-Based Cognitive Behavioral Therapy (iCBT) Program for Ontario Adults During the COVID-19 Pandemic: Qualitative Study. JMIR Formative Research 2024;8:e50113 View
  71. Armaou M, Pears M, Konstantinidis S, Blake H. Evolution of Primary Research Studies in Digital Interventions for Mental Well-Being Promotion from 2004 to 2023: A Bibliometric Analysis of Studies on the Web of Science. International Journal of Environmental Research and Public Health 2024;21(3):375 View
  72. Casu M, Caponnetto P. Breathing tech: digital health innovations for managing asthma-related psychological dimensions. Exploration of Digital Health Technologies 2024:46 View
  73. Ross D, McCallum N, Truuvert A, Butt A, Behdinan T, Rojas D, Soklaridis S, Vigod S. The development and evaluation of a virtual, asynchronous, trauma-focused treatment program for adult survivors of childhood interpersonal trauma. Journal of Mental Health 2024:1 View
  74. Naef A, Coduti E, Windisch P. The Anonymous Data Warehouse: A Hands-On Framework for Anonymizing Data From Digital Health Applications. Cureus 2024 View
  75. Caponnetto P, Prezzavento G, Casu M, Polosa R, Quattropani M. Psychological Factors, Digital Health Technologies, and Best Asthma Management as Three Fundamental Components in Modern Care: A Narrative Review. Applied Sciences 2024;14(8):3365 View
  76. Sudarshan S, Mehrotra S, Thirthalli J. Effectiveness of Blended Internet-based Self-help and Face-to-face Intervention for Depression: A Pilot Study from India. Indian Journal of Psychological Medicine 2024 View
  77. Abouzeid N, Lal S, Titi M. The role of sociodemographic factors on the acceptability of digital mental health care: A scoping review protocol. PLOS ONE 2024;19(4):e0301886 View
  78. Welsh E, McIntosh J, Vuong A, Cloud Z, Hartley E, Boyd J. Design of digital mental health platforms for family member co-completion: Scoping Review (Preprint). Journal of Medical Internet Research 2023 View

Books/Policy Documents

  1. Andersson G. Mental Health in a Digital World. View
  2. Andersson G, Carlbring P. Comprehensive Clinical Psychology. View