This paper is in the following e-collection/theme issue:

Consumer & Patient Education and Shared-Decision Making (688) Digital Health Reviews (1318)

Published on in Vol 17, No 12 (2015): December

Internet-Based Direct-to-Consumer Genetic Testing: A Systematic Review

Internet-Based Direct-to-Consumer Genetic Testing: A Systematic Review

Internet-Based Direct-to-Consumer Genetic Testing: A Systematic Review

Authors of this article:

Loredana Covolo1 Author Orcid Image ;   Sara Rubinelli2 Author Orcid Image ;   Elisabetta Ceretti1 Author Orcid Image ;   Umberto Gelatti1 Author Orcid Image
Article Authors Cited by (102) Tweetations (29) Metrics

Journals

  1. Roberts J, Middleton A. Genetics in the 21st Century: Implications for patients, consumers and citizens. F1000Research 2018;6:2020 View
  2. Rutgers E, Balmana J, Beishon M, Benn K, Evans D, Mansel R, Pharoah P, Perry Skinner V, Stoppa-Lyonnet D, Travado L, Wyld L. European Breast Cancer Council manifesto 2018: Genetic risk prediction testing in breast cancer. European Journal of Cancer 2019;106:45 View
  3. Phillips S, Ali M, Modrich C, Oke S, Elokda A, Laddu D, Bond S. Advances in Health Technology Use and Implementation in the Era of Healthy Living: Implications for Precision Medicine. Progress in Cardiovascular Diseases 2019;62(1):44 View
  4. Park S, Thigpen J, Lee I. Coverage of pharmacogenetic tests by private health insurance companies. Journal of the American Pharmacists Association 2020;60(2):352 View
  5. Allen C, Gabriel J, Flynn M, Cunningham T, Wang C. The impact of raw DNA availability and corresponding online interpretation services: A mixed-methods study. Translational Behavioral Medicine 2018;8(1):105 View
  6. Schwartz L, Woloshin S. Medical Marketing in the United States, 1997-2016. JAMA 2019;321(1):80 View
  7. Kalokairinou L, Borry P, Howard H. Attitudes and experiences of European clinical geneticists towards direct-to-consumer genetic testing: a qualitative interview study. New Genetics and Society 2019;38(4):410 View
  8. Savard J, Hickerton C, Metcalfe S, Gaff C, Middleton A, Newson A. From Expectations to Experiences: Consumer Autonomy and Choice in Personal Genomic Testing. AJOB Empirical Bioethics 2020;11(1):63 View
  9. Dong Y, Branscum P. What Motivates Individuals to Get Obesity Related Direct-To-Consumer Genetic Tests? A Reasoned Action Approach. American Journal of Health Education 2019;50(6):356 View
  10. Hoxhaj I, Stojanovic J, Boccia S. European citizens’ perspectives on direct-to-consumer genetic testing: an updated systematic review. European Journal of Public Health 2023;33(5):947 View
  11. Peterson E, Chou W, Gaysynsky A, Krakow M, Elrick A, Khoury M, Kaphingst K. Communication of cancer-related genetic and genomic information: A landscape analysis of reviews. Translational Behavioral Medicine 2018;8(1):59 View
  12. Littlejohn P, Cop I, Brown E, Afroze R, Davison K. Comparison of Nutrigenomics Technology Interface Tools for Consumers and Health Professionals: Protocol for a Mixed-Methods Study. JMIR Research Protocols 2018;7(6):e115 View
  13. Abrahams M, Frewer L, Bryant E, Stewart-Knox B. Perceptions and experiences of early-adopting registered dietitians in integrating nutrigenomics into practice. British Food Journal 2018;120(4):763 View
  14. Thiebes S, Toussaint P, Ju J, Ahn J, Lyytinen K, Sunyaev A. Valuable Genomes: Taxonomy and Archetypes of Business Models in Direct-to-Consumer Genetic Testing. Journal of Medical Internet Research 2020;22(1):e14890 View
  15. Garmany R, Lee C, Sharp R, Kullo I. Failure to follow up on a medically actionable finding from direct to consumer genetic testing: A case report. Molecular Genetics & Genomic Medicine 2020;8(6) View
  16. Rankin A, Bunting B, Poínhos R, van der Lans I, Fischer A, Kuznesof S, Almeida M, Markovina J, Frewer L, Stewart-Knox B. Food choice motives, attitude towards and intention to adopt personalised nutrition. Public Health Nutrition 2018;21(14):2606 View
  17. Savard J, Hickerton C, Tytherleigh R, Terrill B, Turbitt E, Newson A, Wilson B, Gray K, Gaff C, Middleton A, Stackpoole E, Metcalfe S. Australians’ views and experience of personal genomic testing: survey findings from the Genioz study. European Journal of Human Genetics 2019;27(5):711 View
  18. Gordon E, Babu D, Laney D. The future is now: Technology's impact on the practice of genetic counseling. American Journal of Medical Genetics Part C: Seminars in Medical Genetics 2018;178(1):15 View
  19. Vlahovich N, Hughes D, Griffiths L, Wang G, Pitsiladis Y, Pigozzi F, Bachl N, Eynon N. Genetic testing for exercise prescription and injury prevention: AIS-Athlome consortium-FIMS joint statement. BMC Genomics 2017;18(S8) View
  20. Pàmpols Ros T, García Sagredo J, Pérez Aytés A, Díaz de Bustamante A. Pruebas genéticas de venta directa a los consumidores. Perspectiva de la Comisión de Ética de la Asociación Española de Genética Humana. Medicina Clínica 2019;153(1):35 View
  21. Metcalfe S, Hickerton C, Savard J, Terrill B, Turbitt E, Gaff C, Gray K, Middleton A, Wilson B, Newson A. Australians’ views on personal genomic testing: focus group findings from the Genioz study. European Journal of Human Genetics 2018;26(8):1101 View
  22. Araujo Almeida V, Littlejohn P, Cop I, Brown E, Afroze R, Davison K. Comparison of Nutrigenomics Technology Interface Tools for Consumers and Health Professionals: A Sequential Explanatory Mixed Methods Investigation. Journal of Medical Internet Research 2019;21(6):e12580 View
  23. Kang K, Sun X, Wang L, Yao X, Tang S, Deng J, Wu X, Research Team W, Yang C, Chen G. Direct‐to‐consumer genetic testing in China and its role in GWAS discovery and replication. Quantitative Biology 2021;9(2):201 View
  24. Tiller J, Lacaze P. Regulation of Internet-based Genetic Testing: Challenges for Australia and Other Jurisdictions. Frontiers in Public Health 2018;6 View
  25. Bluth M. Introduction: Molecular Medicine in the Common Era. Clinics in Laboratory Medicine 2018;38(2):209 View
  26. Yin Z, Song L, Clayton E, Malin B, MacLure K. Health and kinship matter: Learning about direct-to-consumer genetic testing user experiences via online discussions. PLOS ONE 2020;15(9):e0238644 View
  27. Hurlimann T, Robitaille J, Vohl M, Godard B. Ethical Considerations in the Implementation of Nutrigenetics/Nutrigenomics. Personalized Medicine 2017;14(1):75 View
  28. Roberts J, Middleton A. Genetics in the 21st Century: Implications for patients, consumers and citizens. F1000Research 2017;6:2020 View
  29. Balasopoulou A, Mooy F, Baker D, Mitropoulou C, Skoufas E, Bulgiba A, Katsila T, Patrinos G. Advancing Global Precision Medicine: An Overview of Genomic Testing and Counseling Services in Malaysia. OMICS: A Journal of Integrative Biology 2017;21(12):733 View
  30. Schaper M, Wöhlke S, Schicktanz S. “I would rather have it done by a doctor”—laypeople’s perceptions of direct-to-consumer genetic testing (DTC GT) and its ethical implications. Medicine, Health Care and Philosophy 2019;22(1):31 View
  31. Dekeuwer C. « Faire l’autruche ou l’idiot rationnel ? De l’attitude la plus sage à adopter face aux prédictions proposées par la médecine génomique ». Éthique & Santé 2018;15(4):238 View
  32. Horowitz A, Saperstein A, Little J, Maiers M, Hollenbach J. Consumer (dis-)interest in genetic ancestry testing: the roles of race, immigration, and ancestral certainty. New Genetics and Society 2019;38(2):165 View
  33. Turrini M, Prainsack B. Beyond clinical utility: The multiple values of DTC genetics. Applied & Translational Genomics 2016;8:4 View
  34. Turrini M. Online Genomes: Problematizing the disruptiveness of direct‐to‐consumer genetic tests. Sociology Compass 2018;12(11) View
  35. Haeusermann T, Fadda M, Blasimme A, Tzovaras B, Vayena E. Genes wide open: Data sharing and the social gradient of genomic privacy. AJOB Empirical Bioethics 2018;9(4):207 View
  36. Ballard L, Horton R, Fenwick A, Lucassen A. Genome sequencing in healthcare: understanding the UK general public’s views and implications for clinical practice. European Journal of Human Genetics 2020;28(2):155 View
  37. Molster C, Bowman F, Bilkey G, Cho A, Burns B, Nowak K, Dawkins H. The Evolution of Public Health Genomics: Exploring Its Past, Present, and Future. Frontiers in Public Health 2018;6 View
  38. Stewart K, Wesselius A, Schreurs M, Schols A, Zeegers M. Behavioural changes, sharing behaviour and psychological responses after receiving direct-to-consumer genetic test results: a systematic review and meta-analysis. Journal of Community Genetics 2018;9(1):1 View
  39. Pàmpols Ros T, García Sagredo J, Pérez Aytés A, Díaz de Bustamante A. Directed to consumer genetic testing. Perspective from the Ethics commission of the Spanish Society for Human Genetics. Medicina Clínica (English Edition) 2019;153(1):35 View
  40. Chokoshvili D, Vears D, Borry P. Growing complexity of (expanded) carrier screening: Direct-to-consumer, physician-mediated, and clinic-based offers. Best Practice & Research Clinical Obstetrics & Gynaecology 2017;44:57 View
  41. Lucchini V. Nutrigenetics in practice: little is better than nothing. Current Opinion in Food Science 2017;16:114 View
  42. King E, Mahon S. Genetic Testing: Challenges and Changes in Testing for Hereditary Cancer Syndromes. Clinical Journal of Oncology Nursing 2017;21(5):589 View
  43. Hall J, Gertz R, Amato J, Pagliari C. Transparency of genetic testing services for ‘health, wellness and lifestyle’: analysis of online prepurchase information for UK consumers. European Journal of Human Genetics 2017;25(8):908 View
  44. Haga S. First Responder to Genomic Information: A Guide for Primary Care Providers. Molecular Diagnosis & Therapy 2019;23(4):459 View
  45. Ortega-Paredes D, Larrea-Álvarez C, Herrera M, Fernandez-Moreira E, Larrea-Álvarez M. Assessing knowledge of genetics in undergraduate students in Quito, Ecuador. F1000Research 2019;8:290 View
  46. Drabsch T, Holzapfel C. A Scientific Perspective of Personalised Gene-Based Dietary Recommendations for Weight Management. Nutrients 2019;11(3):617 View
  47. Wade C. What Is the Psychosocial Impact of Providing Genetic and Genomic Health Information to Individuals? An Overview of Systematic Reviews. Hastings Center Report 2019;49(S1) View
  48. Ortega-Paredes D, Larrea-Álvarez C, Herrera M, Fernandez-Moreira E, Larrea-Álvarez M. Assessing knowledge of genetics in undergraduate students in Quito, Ecuador. F1000Research 2019;8:290 View
  49. Pettitt D, Smith J, Meadows N, Arshad Z, Schuh A, DiGiusto D, Bountra C, Holländer G, Barker R, Brindley D. Regulatory barriers to the advancement of precision medicine. Expert Review of Precision Medicine and Drug Development 2016;1(3):319 View
  50. Cumming G, Morris E, Simpson P, French T, Kahana E, Luciano J, Molik D. The future of post-reproductive health – The role of the Internet, the Web, information provision and access. Post Reproductive Health 2016;22(3):123 View
  51. Du L, Wang M. Genetic Privacy and Data Protection: A Review of Chinese Direct-to-Consumer Genetic Test Services. Frontiers in Genetics 2020;11 View
  52. Millward M, Tiller J, Bogwitz M, Kincaid H, Taylor S, Trainer A, Lacaze P. Impact of direct-to-consumer genetic testing on Australian clinical genetics services. European Journal of Medical Genetics 2020;63(9):103968 View
  53. Schienda J, Stopfer J. Cancer Genetic Counseling—Current Practice and Future Challenges. Cold Spring Harbor Perspectives in Medicine 2020;10(6):a036541 View
  54. Schneider R, Myers T, Rowbotham H, Luff M, Amodeo K, Sharma S, Wilson R, Jensen-Roberts S, Auinger P, McDermott M, Alcalay R, Biglan K, Kinel D, Tanner C, Winter-Evans R, Augustine E, Cannon P, Holloway R, Dorsey E. A Virtual Cohort Study of Individuals at Genetic Risk for Parkinson’s Disease: Study Protocol and Design. Journal of Parkinson's Disease 2020;10(3):1195 View
  55. Drabsch T, Gatzemeier J, Pfadenhauer L, Hauner H, Holzapfel C. Associations between Single Nucleotide Polymorphisms and Total Energy, Carbohydrate, and Fat Intakes: A Systematic Review. Advances in Nutrition 2018;9(4):425 View
  56. Lydon E, Ko E, Tsalik E. The host response as a tool for infectious disease diagnosis and management. Expert Review of Molecular Diagnostics 2018;18(8):723 View
  57. Braakhuis A, Monnard C, Ellis A, Rozga M. Consensus Report of the Academy of Nutrition and Dietetics: Incorporating Genetic Testing into Nutrition Care. Journal of the Academy of Nutrition and Dietetics 2021;121(3):545 View
  58. Calabrò G, Sassano M, Tognetto A, Boccia S. Citizens' Attitudes, Knowledge, and Educational Needs in the Field of Omics Sciences: A Systematic Literature Review. Frontiers in Genetics 2020;11 View
  59. Oliveri S, Marton G, Vergani L, Cutica I, Gorini A, Spinella F, Pravettoni G. Genetic Testing Consumers in Italy: A Preliminary Investigation of the Socio-Demographic Profile, Health-Related Habits, and Decision Purposes. Frontiers in Public Health 2020;8 View
  60. Majumder M, Guerrini C, McGuire A. Direct-to-Consumer Genetic Testing: Value and Risk. Annual Review of Medicine 2021;72(1):151 View
  61. Bayer S, Drabsch T, Schauberger G, Hauner H, Holzapfel C. Knowledge, opinions and expectations of adults concerning personalised genotype-based dietary recommendations: a German survey. Public Health Nutrition 2021;24(7):1916 View
  62. Nill A, Laczniak G. Direct-to-Consumer Genetic Testing and Its Marketing: Emergent Ethical and Public Policy Implications. Journal of Business Ethics 2022;175(4):669 View
  63. Taylor-Phillips S, Berhane S, Sitch A, Freeman K, Price M, Davenport C, Geppert J, Harris I, Osokogu O, Skrybant M, Deeks J. Information given by websites selling home self-sampling COVID-19 tests: an analysis of accuracy and completeness. BMJ Open 2020;10(11):e042453 View
  64. Koop A, Ghoz H, Stancampiano F, Nordelo K, Palmer W. A survey of lifestyle habits, physician counseling, and direct-to consumer genetic testing in patients with hereditary hemochromatosis. Clinics and Research in Hepatology and Gastroenterology 2021;45(2):101658 View
  65. Oliveri S, Cincidda C, Ongaro G, Cutica I, Gorini A, Spinella F, Fiorentino F, Baldi M, Pravettoni G. What people really change after genetic testing (GT) performed in private labs: results from an Italian study. European Journal of Human Genetics 2022;30(1):62 View
  66. Hui V, Li H, Chow J, Ng C, Lui C, Fung J, Mak C, Chung B, Lau K. Understanding and perception of direct‐to‐consumer genetic testing in Hong Kong. Journal of Genetic Counseling 2021;30(6):1640 View
  67. Bayer S, Holzapfel C. Personalisierte, genbasierte Ernährungsempfehlungen zur Gewichtsreduktion. Ernährung & Medizin 2021;36(02):53 View
  68. Peck L, Borle K, Folkersen L, Austin J. Why do people seek out polygenic risk scores for complex disorders, and how do they understand and react to results?. European Journal of Human Genetics 2022;30(1):81 View
  69. Bates M. Direct-To-Consumer Genetic Testing: Is the Public Ready for Simple, At-Home DNA Tests to Detect Disease Risk?. IEEE Pulse 2018;9(6):11 View
  70. Obayashi C, Asahara K, Umeda M. Difficulties in providing genetic consultations by public health nurses in Japan. Public Health Nursing 2022;39(5):1107 View
  71. Ormondroyd E, Border P, Hayward J, Papanikitas A. Genomic health data generation in the UK: a 360 view. European Journal of Human Genetics 2022;30(7):782 View
  72. Kopanitsa G. Study of patients' attitude to automatic interpretation of laboratory test results and its influence on follow-up rate. BMC Medical Informatics and Decision Making 2022;22(1) View
  73. Foss K, O’Daniel J, Berg J, Powell S, Cadigan R, Kuczynski K, Milko L, Saylor K, Roberts M, Weck K, Henderson G. The Rise of Population Genomic Screening: Characteristics of Current Programs and the Need for Evidence Regarding Optimal Implementation. Journal of Personalized Medicine 2022;12(5):692 View
  74. Lowes K, Borle K, Folkersen L, Austin J. A qualitative study exploring the consumer experience of receiving self-initiated polygenic risk scores from a third-party website. European Journal of Human Genetics 2023;31(4):424 View
  75. Martins M, Murry L, Telford L, Moriarty F. Direct-to-consumer genetic testing: an updated systematic review of healthcare professionals’ knowledge and views, and ethical and legal concerns. European Journal of Human Genetics 2022;30(12):1331 View
  76. Cernat A, Bashir N, Ungar W. Considerations for developing regulations for direct-to-consumer genetic testing: a scoping review using the 3-I framework. Journal of Community Genetics 2022;13(2):155 View
  77. Allen C, Andersen B, Khoury M, Roberts M. Current Social Media Conversations about Genetics and Genomics in Health: A Twitter-Based Analysis. Public Health Genomics 2018;21(1-2):93 View
  78. Beccia F, Hoxhaj I, Sassano M, Stojanovic J, Acampora A, Pastorino R, Boccia S. Survey of Professionals of the European Public Health Association (EUPHA) towards Direct-to-Consumer Genetic Testing. European Journal of Public Health 2023;33(1):139 View
  79. Ongaro G, Brivio E, Cincidda C, Oliveri S, Spinella F, Steinberger D, Cutica I, Gorini A, Pravettoni G. Genetic testing users in Italy and Germany: Health orientation, health‐related habits, and psychological profile. Molecular Genetics & Genomic Medicine 2022;10(3) View
  80. Lee J, Kwon K. Development of customized inner beauty products and customized cosmetics apps according to the use of NRF2 through DTC genetic testing after the COVID‐19 pandemic. Journal of Cosmetic Dermatology 2022;21(6):2288 View
  81. Banerjee S, Sussman A, Schofield E, Guest D, Dailey Y, Schwartz M, Buller D, Hunley K, Kaphingst K, Berwick M, Hay J. “Let’s Talk about Skin Cancer”: Examining Association between Family Communication about Skin Cancer, Perceived Risk, and Sun Protection Behaviors. Journal of Health Communication 2021;26(8):576 View
  82. Grandhi S, Plotnick L. Do I Spit or Do I Pass?. Proceedings of the ACM on Human-Computer Interaction 2022;6(GROUP):1 View
  83. Nolan J, Ormondroyd E. Direct‐to‐consumer genetic tests providing health risk information: A systematic review of consequences for consumers and health services. Clinical Genetics 2023;104(1):3 View
  84. Lubin I, Astles J, Bunn J, Cornish N, Lazaro G, Marshall A, Stang H, De Jesús V. The Clinical Laboratory Is an Integral Component to Health Care Delivery : An Expanded Representation of the Total Testing Process. American Journal of Clinical Pathology 2023;160(2):124 View
  85. Jaya H, Idayu Matusin S, Mustapa A, Abdullah M, Haji Abdul Hamid M. Public knowledge of and attitudes toward genetics and genetic testing in Brunei Darussalam. Frontiers in Genetics 2023;14 View
  86. Cutica I, Cincidda C, Oliveri S, Mainetti R, Borghese N, Pravettoni G. Effectiveness of Serious Games in Improving Genetic Literacy and Genetic Risk Awareness in the General Public: A Pilot Study. Games for Health Journal 2024;13(2):75 View
  87. Nienaber-Rousseau C. Understanding and applying gene–environment interactions: a guide for nutrition professionals with an emphasis on integration in African research settings. Nutrition Reviews 2024 View
  88. Cook A. Recommendations for Improving the Use of Direct-To-Consumer Genetic Testing Databases in Law Enforcement Investigations. Journal of Science Policy & Governance 2024;24(01) View
  89. Yim J. Current Landscape and Perspectives of Direct-to-Consumer Genetic Testing. Laboratory Medicine Online 2024;14(3):191 View
  90. Onstwedder S, Jansen M, Cornel M, Rigter T. Policy Guidance for Direct-to-Consumer Genetic Testing Services: Framework Development Study. Journal of Medical Internet Research 2024;26:e47389 View
  91. Bojarczuk A. Ethical Aspects of Human Genome Research in Sports—A Narrative Review. Genes 2024;15(9):1216 View
  92. Oyovwi M, Ohwin E, Rotu R, Olowe T. Internet-Based Abnormal Chromosomal Diagnosis During Pregnancy Using a Noninvasive Innovative Approach to Detecting Chromosomal Abnormalities in the Fetus: Scoping Review. JMIR Bioinformatics and Biotechnology 2024;5:e58439 View
  93. Penna L, Amemiya R, Pires T, Bonasser L, Carvalheira L, Fridman C, Mingroni-Netto R, Naslavsky M, di Lazzaro Filho R. Motivations, perceptions and impacts of direct-to-consumer genetic testing among users in Brazil. Journal of Community Genetics 2024 View

Books/Policy Documents

  1. Volpi P, Bisciotti G. Muscle Injury in the Athlete. View
  2. Braconi D, Cicaloni V, Spiga O, Santucci A. Trends in Personalized Nutrition. View
  3. Barbosa M, Catalano D, Fiore D. Computer Security – ESORICS 2017. View
  4. Mitchell I, Guichon J. Ethics in Pediatrics. View
  5. Colson N, Adamski M. Emerging Technologies and Work-Integrated Learning Experiences in Allied Health Education. View
  6. Pastorino R, Lang M, Zawati M, Calabrò G, Hoxhaj I, Houwink E, Sassano M, Boccia S. Personalised Health Care. View
  7. Benedetti D, Marron J. Ethical Challenges in Cancer Diagnosis and Therapy. View
  8. Pointner A, Haslberger A. Advances in Precision Nutrition, Personalization and Healthy Aging. View
  9. Ducournau P. S’entreprendre avec ses gènes. View