Published on in Vol 10, No 1 (2008): Jan-Mar

Effectiveness of a Web-Based Self-Help Intervention for Symptoms of Depression, Anxiety, and Stress: Randomized Controlled Trial

Effectiveness of a Web-Based Self-Help Intervention for Symptoms of Depression, Anxiety, and Stress: Randomized Controlled Trial

Effectiveness of a Web-Based Self-Help Intervention for Symptoms of Depression, Anxiety, and Stress: Randomized Controlled Trial

Authors of this article:

Annemieke van Straten ;   Pim Cuijpers ;   Niels Smits


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  118. van Ballegooijen W, Cuijpers P, van Straten A, Karyotaki E, Andersson G, Smit J, Riper H, García A. Adherence to Internet-Based and Face-to-Face Cognitive Behavioural Therapy for Depression: A Meta-Analysis. PLoS ONE 2014;9(7):e100674 View
  119. Hofer P, Waadt M, Aschwanden R, Milidou M, Acker J, Meyer A, Lieb R, Gloster A. Self-help for stress and burnout without therapist contact: An online randomised controlled trial. Work & Stress 2018;32(2):189 View
  120. Kolovos S, Kenter R, Bosmans J, Beekman A, Cuijpers P, Kok R, van Straten A. Economic evaluation of Internet-based problem-solving guided self-help treatment in comparison with enhanced usual care for depressed outpatients waiting for face-to-face treatment: A randomized controlled trial. Journal of Affective Disorders 2016;200:284 View
  121. Boenisch S, Kocalevent R, Matschinger H, Mergl R, Wimmer-Brunauer C, Tauscher M, Kramer D, Hegerl U, Bramesfeld A. Who receives depression-specific treatment? A secondary data-based analysis of outpatient care received by over 780,000 statutory health-insured individuals diagnosed with depression. Social Psychiatry and Psychiatric Epidemiology 2012;47(3):475 View
  122. Hill R, Moran N. Social marketing meets interactive media. International Journal of Advertising 2011;30(5):815 View
  123. Eklund C, Elfström M, Eriksson Y, Söderlund A. User experiences from a web-based, self-management programme: struggling with what I need when stress management is about me. European Journal of Physiotherapy 2019;21(1):39 View
  124. KLEMM P, HAYES E, DIEFENBECK C, MILCAREK B. Online Support for Employed Informal Caregivers. CIN: Computers, Informatics, Nursing 2014;32(1):10 View
  125. Boeschoten R, Dekker J, Uitdehaag B, Polman C, Collette E, Cuijpers P, Beekman A, van Oppen P. Internet-based self-help treatment for depression in multiple sclerosis: study protocol of a randomized controlled trial. BMC Psychiatry 2012;12(1) View
  126. van Luenen S, Kraaij V, Spinhoven P, Garnefski N. An Internet-based self-help intervention for people with HIV and depressive symptoms: study protocol for a randomized controlled trial. Trials 2016;17(1) View
  127. Tossmann D, Jonas B, Tensil M, Lang P, Strüber E. A Controlled Trial of an Internet-Based Intervention Program for Cannabis Users. Cyberpsychology, Behavior, and Social Networking 2011;14(11):673 View
  128. Geraedts A, Kleiboer A, Wiezer N, van Mechelen W, Cuijpers P. Web-based guided self-help for employees with depressive symptoms (Happy@Work): design of a randomized controlled trial. BMC Psychiatry 2013;13(1) View
  129. Donkin L, Hickie I, Christensen H, Naismith S, Neal B, Cockayne N, Glozier N. Sampling bias in an internet treatment trial for depression. Translational Psychiatry 2012;2(10):e174 View
  130. Hasson H, Brown C, Hasson D. Factors associated with high use of a workplace web-based stress management program in a randomized controlled intervention study. Health Education Research 2010;25(4):596 View
  131. Carter W, Fergus K, Ahmad S, McLeod D, Stephen J. Defining the Role of the Online Therapeutic Facilitator: Principles and Guidelines Developed for Couplelinks, an Online Support Program for Couples Affected by Breast Cancer. JMIR Cancer 2015;1(1):e4 View
  132. Walter U, Krugmann C, Plaumann M. Burn-out wirksam prävenieren?. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 2012;55(2):172 View
  133. Eklund C, Elfström M, Eriksson Y, Söderlund A, Travlos A. Development of the web application My Stress Control—Integrating theories and existing evidence. Cogent Psychology 2018;5(1):1489457 View
  134. Schuurhuizen C, Braamse A, Beekman A, Bomhof-Roordink H, Bosmans J, Cuijpers P, Hoogendoorn A, Konings I, van der Linden M, Neefjes E, Verheul H, Dekker J. Screening and treatment of psychological distress in patients with metastatic colorectal cancer: study protocol of the TES trial. BMC Cancer 2015;15(1) View
  135. Goetz K, Loew T, Hornung R, Cojocaru L, Lahmann C, Tritt K. Primary Prevention Programme for Burnout-Endangered Teachers: Follow-Up Effectiveness of a Combined Group and Individual Intervention of AFA Breathing Therapy. Evidence-Based Complementary and Alternative Medicine 2013;2013:1 View
  136. Farhangi M, Jahangiry L, Mirinazhad M, Shojaeezade D, Montazeri A, Yaghoubi A. A web-based interactive lifestyle modification program improves lipid profile and serum adiponectin concentrations in patients with metabolic syndrome: the “Red Ruby” study. International Journal of Diabetes in Developing Countries 2017;37(1):21 View
  137. Persson Asplund R, Dagöö J, Fjellström I, Niemi L, Hansson K, Zeraati F, Ziuzina M, Geraedts A, Ljótsson B, Carlbring P, Andersson G. Internet-based stress management for distressed managers: results from a randomised controlled trial. Occupational and Environmental Medicine 2018;75(2):105 View
  138. Yu L, Wu C, Jang F. Psychiatric document retrieval using a discourse-aware model. Artificial Intelligence 2009;173(7-8):817 View
  139. Hedman E, Ljótsson B, Lindefors N. Cognitive behavior therapy via the Internet: a systematic review of applications, clinical efficacy and cost–effectiveness. Expert Review of Pharmacoeconomics & Outcomes Research 2012;12(6):745 View
  140. Latalova K, Prasko J, Kamaradova D, Jelenova D, Ociskova M, Sedlackova Z. Internet Psychoeducation for Bipolar Affective Disorder: Basis for Preparation and First Experiences. Psychiatric Quarterly 2014;85(2):241 View
  141. Christensen H, Griffiths K, Farrer L. Adherence in Internet Interventions for Anxiety and Depression. Journal of Medical Internet Research 2009;11(2):e13 View
  142. Braamse A, van Meijel B, Visser O, van Oppen P, Boenink A, Eeltink C, Cuijpers P, Huijgens P, Beekman A, Dekker J. Distress and quality of life after autologous stem cell transplantation: a randomized clinical trial to evaluate the outcome of a web-based stepped care intervention. BMC Cancer 2010;10(1) View
  143. Servant D, Leterme A, Barasino O, Rougegrez L, Duhamel A, Vaiva G. Efficacy of Seren@ctif, a Computer-Based Stress Management Program for Patients With Adjustment Disorder With Anxiety: Protocol for a Controlled Trial. JMIR Research Protocols 2017;6(10):e190 View
  144. Seekles W, van Straten A, Beekman A, van Marwijk H, Cuijpers P. Stepped care treatment for depression and anxiety in primary care. a randomized controlled trial. Trials 2011;12(1) View
  145. Kelders S, Kok R, Ossebaard H, Van Gemert-Pijnen J. Persuasive System Design Does Matter: a Systematic Review of Adherence to Web-based Interventions. Journal of Medical Internet Research 2012;14(6):e152 View
  146. Paul C, Carey M, Sanson-Fisher R, Houlcroft L, Turon H. The impact of web-based approaches on psychosocial health in chronic physical and mental health conditions. Health Education Research 2013;28(3):450 View
  147. Zhao D, Lustria M, Hendrickse J. Systematic review of the information and communication technology features of web- and mobile-based psychoeducational interventions for depression. Patient Education and Counseling 2017;100(6):1049 View
  148. Boele F, Verdonck-de Leeuw I, Cuijpers P, Reijneveld J, Heimans J, Klein M. Internet-based guided self-help for glioma patients with depressive symptoms: design of a randomized controlled trial. BMC Neurology 2014;14(1) View
  149. Elbers N, Akkermans A, Cuijpers P, Bruinvels D. Effectiveness of a web-based intervention for injured claimants: a randomized controlled trial. Trials 2013;14(1):227 View
  150. Gnagnarella P, Misotti A, Santoro L, Akoumianakis D, Del Campo L, De Lorenzo F, Lombardo C, Milolidakis G, Sullivan R, McVie J. Nutritional Online Information for Cancer Patients: a Randomized Trial of an Internet Communication Plus Social Media Intervention. Journal of Cancer Education 2016;31(3):472 View
  151. Knapstad M, Sæther S, Hensing G, Smith O. Prompt Mental Health Care (PMHC): work participation and functional status at 12 months post-treatment. BMC Health Services Research 2020;20(1) View
  152. Aronson I, Marsch L, Acosta M. Using findings in multimedia learning to inform technology-based behavioral health interventions. Translational Behavioral Medicine 2013;3(3):234 View
  153. Boeschoten R, Nieuwenhuis M, van Oppen P, Uitdehaag B, Polman C, Collette E, Cuijpers P, Beekman A, Dekker J. Feasibility and outcome of a web-based self-help intervention for depressive symptoms in patients with multiple sclerosis: A pilot study. Journal of the Neurological Sciences 2012;315(1-2):104 View
  154. Johansson R, Andersson G. Internet-based psychological treatments for depression. Expert Review of Neurotherapeutics 2012;12(7):861 View
  155. Ünlü Ince B, Cuijpers P, van 't Hof E, Riper H. Reaching and recruiting Turkish migrants for a clinical trial through Facebook: A process evaluation. Internet Interventions 2014;1(2):74 View
  156. Kenter R, Warmerdam L, Brouwer-Dudokdewit C, Cuijpers P, van Straten A. Guided online treatment in routine mental health care: an observational study on uptake, drop-out and effects. BMC Psychiatry 2013;13(1) View
  157. Novakova B, Harris P, Rawlings G, Reuber M. Coping with stress: A pilot study of a self-help stress management intervention for patients with epileptic or psychogenic nonepileptic seizures. Epilepsy & Behavior 2019;94:169 View
  158. Geraedts A, Kleiboer A, Wiezer N, van Mechelen W, Cuijpers P. Short-Term Effects of a Web-Based Guided Self-Help Intervention for Employees With Depressive Symptoms: Randomized Controlled Trial. Journal of Medical Internet Research 2014;16(5):e121 View
  159. Riper H. Online preventie en kortdurende behandeling van depressie: haalbaar, schaalbaar en effectief?. Bijblijven 2011;27(8):24 View
  160. Cowpertwait L, Clarke D. Effectiveness of Web-based Psychological Interventions for Depression: A Meta-analysis. International Journal of Mental Health and Addiction 2013;11(2):247 View
  161. Gökkaya F. Prevention of Occupational Burnout. İş ve İnsan Dergisi 2019;6(1):29 View
  162. Salisbury C, O’Cathain A, Thomas C, Edwards L, Montgomery A, Hollinghurst S, Large S, Nicholl J, Pope C, Rogers A, Lewis G, Fahey T, Yardley L, Brownsell S, Dixon P, Drabble S, Esmonde L, Foster A, Garner K, Gaunt D, Horspool K, Man M, Rowsell A, Segar J. An evidence-based approach to the use of telehealth in long-term health conditions: development of an intervention and evaluation through pragmatic randomised controlled trials in patients with depression or raised cardiovascular risk. Programme Grants for Applied Research 2017;5(1):1 View
  163. Ebert D, Lehr D, Baumeister H, Boß L, Riper H, Cuijpers P, Reins J, Buntrock C, Berking M. GET.ON Mood Enhancer: efficacy of Internet-based guided self-help compared to psychoeducation for depression: an investigator-blinded randomised controlled trial. Trials 2014;15(1) View
  164. Braamse A, van Meijel B, Visser O, Boenink A, Cuijpers P, Eeltink C, Hoogendoorn A, van Marwijk Kooy M, van Oppen P, Huijgens P, Beekman A, Dekker J. A randomized clinical trial on the effectiveness of an intervention to treat psychological distress and improve quality of life after autologous stem cell transplantation. Annals of Hematology 2016;95(1):105 View
  165. Liou S, Wang P, Cheng C. Longitudinal study of perinatal maternal stress, depressive symptoms and anxiety. Midwifery 2014;30(6):795 View
  166. Cuijpers P, Smit F, Beekman A. Preventie van depressie: een overzicht. Psychologie en Gezondheid 2010;38(1):28 View
  167. Farrer L, Christensen H, Griffiths K, Mackinnon A, Domschke K. Internet-Based CBT for Depression with and without Telephone Tracking in a National Helpline: Randomised Controlled Trial. PLoS ONE 2011;6(11):e28099 View
  168. Frasquilho D, Matias R, Grácio J, Sousa B, Luís-Ferreira F, Leal J, Cardoso F, Oliveira-Maia A. Protocol for the Implementation and Assessment of “MoodUP”: A Stepped Care Model Assisted by a Digital Platform to Accelerate Access to Mental Health Care for Cancer Patients Amid the COVID-19 Pandemic. International Journal of Environmental Research and Public Health 2021;18(9):4629 View
  169. Hentati A, Forsell E, Ljótsson B, Lindefors N, Kraepelien M. A self-guided and monitored digital problem-solving intervention for patients with symptoms of depression or anxiety on the waiting list for treatment in routine psychiatric care: feasibility study. BJPsych Open 2022;8(2) View
  170. Nadort E, Schouten R, Boeschoten R, Smets Y, Chandie Shaw P, Vleming L, Dekker M, Westerman M, Hoogeveen E, Bos W, Schouten M, Farhat K, Dekker F, van Oppen P, Broekman B, Siegert C. Internet-based treatment for depressive symptoms in hemodialysis patients: A cluster randomized controlled trial. General Hospital Psychiatry 2022;75:46 View
  171. Foy J, Kelleher K, Laraque D. Enhancing Pediatric Mental Health Care: Strategies for Preparing a Primary Care Practice. Pediatrics 2010;125(Supplement_3):S87 View
  172. Krifa I, Hallez Q, van Zyl L, Braham A, Sahli J, Ben Nasr S, Shankland R. Effectiveness of an online positive psychology intervention among Tunisian healthcare students on mental health and study engagement during the Covid‐19 pandemic. Applied Psychology: Health and Well-Being 2022;14(4):1228 View
  173. Krijnen-de Bruin E, Muntingh A, Bourguignon E, Hoogendoorn A, Maarsingh O, van Balkom A, Batelaan N, van Straten A, van Meijel B. Usage Intensity of a Relapse Prevention Program and Its Relation to Symptom Severity in Remitted Patients With Anxiety and Depression: Pre-Post Study. JMIR Mental Health 2022;9(3):e25441 View
  174. Foy J, Green C, Earls M, Lavin A, Askew G, Baum R, Berger-Jenkins E, Gambon T, Nasir A, Wissow L, Joffe A. Mental Health Competencies for Pediatric Practice. Pediatrics 2019;144(5) View
  175. Timakum T, Xie Q, Song M. Analysis of E-mental health research: mapping the relationship between information technology and mental healthcare. BMC Psychiatry 2022;22(1) View
  176. Markossian T, Boyda J, Taylor J, Etingen B, Modave F, Price R, Kramer H. A Mobile App to Support Self-management of Chronic Kidney Disease: Development Study. JMIR Human Factors 2021;8(4):e29197 View
  177. ÖZER Ö, CEYHAN A. Kendi Kendine Yardım Temelli Çevrimiçi Psikososyal Destek Platformunun Geliştirilmesi. Afet ve Risk Dergisi 2021;4(2):371 View
  178. Zwi S, Isautier J, Webster A, Lambert K, Shepherd H, McCaffery K, Sud K, Saunders J, O'Lone E, Liu N, Kim J, Robbins A, Muscat D. A feasibility study of a best practice health literacy app for Australian adults with chronic kidney disease. PEC Innovation 2022;1:100047 View
  179. Spanhel K, Balci S, Feldhahn F, Bengel J, Baumeister H, Sander L. Cultural adaptation of internet- and mobile-based interventions for mental disorders: a systematic review. npj Digital Medicine 2021;4(1) View
  180. Galkin F, Kochetov K, Keller M, Zhavoronkov A, Etcoff N. Optimizing future well-being with artificial intelligence: self-organizing maps (SOMs) for the identification of islands of emotional stability. Aging 2022;14(12):4935 View
  181. Mamukashvili-Delau M, Koburger N, Dietrich S, Rummel-Kluge C. Efficacy of computer- and/or internet-based cognitive-behavioral guided self-management for depression in adults: a systematic review and meta-analysis of randomized controlled trials. BMC Psychiatry 2022;22(1) View
  182. Lo H, Chen W, Chang S. Tai Chi Training and Educational Intervention Improved Self-care Behaviors and Lowered Blood Pressure in Hypertensive Outpatients. Journal of Comprehensive Nursing Research and Care 2017;2(2) View
  183. Kaufman N. Health Information Technology in the Service of Depression Treatment. Diabetes Spectrum 2010;23(1):5 View
  184. Takagi G. The effect of mechanical feedback on outcome in self-care support tool based on solution-focused brief therapy. Psychotherapy Research 2023:1 View
  185. ÖZER Ö, KÖKSAL B. Üniversite Öğrencilerine Yönelik Ruh Sağlığı Hizmetlerinde İnternet Tabanlı Müdahaleler: Bir Gözden Geçirme. OSMANGAZİ JOURNAL OF MEDICINE 2023 View
  186. Wicaksana A, Apriliyasari R, Tsai P. Effect of self-help interventions on psychological, glycemic, and behavioral outcomes in patients with diabetes: A meta-analysis of randomized controlled trials. International Journal of Nursing Studies 2024;149:104626 View
  187. Mamukashvili-Delau M, Koburger N, Dietrich S, Rummel-Kluge C. Long-Term Efficacy of Internet-Based Cognitive Behavioral Therapy Self-Help Programs for Adults With Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials. JMIR Mental Health 2023;10:e46925 View
  188. Kulke J, Nacke B, Jacobi C. Fostering resilience during the COVID‐19 pandemic via a digital mental health intervention—A pilot study. Mental Health Science 2023;1(3):147 View
  189. Özer Ö, Ceyhan A, Struijs S. User profile of an online cognitive behavioral therapy self-help platform in Turkey. Current Psychology 2024;43(7):6022 View
  190. Bjornstad G, Sonthalia S, Rouse B, Freeman L, Hessami N, Dunne J, Axford N. A comparison of the effectiveness of cognitive behavioural interventions based on delivery features for elevated symptoms of depression in adolescents: A systematic review. Campbell Systematic Reviews 2024;20(1) View
  191. Kolaas K, Berman A, Hedman-Lagerlöf E, Lindsäter E, Hybelius J, Axelsson E. Internet-delivered transdiagnostic psychological treatments for individuals with depression, anxiety or both: a systematic review with meta-analysis of randomised controlled trials. BMJ Open 2024;14(4):e075796 View
  192. Lin J, Sander L, Paganini S, Schlicker S, Ebert D, Berking M, Bengel J, Nobis S, Lehr D, Mittag O, Riper H, Baumeister H. Effectiveness and cost-effectiveness of a guided internet- and mobile-based depression intervention for individuals with chronic back pain: protocol of a multi-centre randomised controlled trial. BMJ Open 2017;7(12):e015226 View

Books/Policy Documents

  1. Olthuis J, Watt M, Bailey K, Hayden J, Stewart S, Olthuis J. Cochrane Database of Systematic Reviews. View
  2. Walter U, Plaumann M, Krugmann C. Burnout for Experts. View
  3. Langrial S. Assistive Technologies for Physical and Cognitive Disabilities. View
  4. Casey P. Principles of Social Psychiatry. View
  5. Thew M. Role Emerging Occupational Therapy. View
  6. Manfrida G, Albertini V, Eisenberg E. Clinical Interventions in Systemic Couple and Family Therapy. View
  7. Håvik R, Wake J, Flobak E, Lundervold A, Guribye F. Internet Science. View
  8. Becker D. Advances in Information and Communication Networks. View
  9. Blasko K, Murphy P. Parenting and Children's Resilience in Military Families. View
  10. Langrial S. Human-Computer Interaction. View
  11. Lehto T. Critical Issues for the Development of Sustainable E-health Solutions. View
  12. Radden J. Philosophical Issues in Pharmaceutics. View
  13. . Lesen macht gesund. View
  14. . Pediatric Psychopharmacology for Primary Care. View
  15. Golbourn-King L, Kotera Y. Current and Future Trends in Health and Medical Informatics. View