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Published on 04.03.14 in Vol 16, No 3 (2014): March

This paper is in the following e-collection/theme issue:

    Original Paper

    Supporting Self-Care for Families of Children With Eczema With a Web-Based Intervention Plus Health Care Professional Support: Pilot Randomized Controlled Trial

    1Primary Care and Population Sciences, University of Southampton, Southampton, United Kingdom

    2Academic Unit of Psychology, Faculty of Social and Human Sciences, University of Southampton, Southampton, United Kingdom

    3Faculty of Medicine, University of Southampton, Southampton, United Kingdom

    Corresponding Author:

    Miriam Santer, MBBChir, MRCGP, PhD

    Primary Care and Population Sciences

    University of Southampton

    Aldermoor Health Centre

    Aldermoor Close

    Southampton, SO16 5ST

    United Kingdom

    Phone: 44 2380241019

    Fax:44 2380701125

    Email:


    ABSTRACT

    Background: Childhood eczema, or childhood atopic dermatitis, causes significant distress to children and their families through sleep disturbance and itch. The main cause of treatment failure is nonuse of prescribed treatments.

    Objective: The objective of this study was to develop and test a Web-based intervention to support families of children with eczema, and to explore whether support from a health care professional (HCP) is necessary to engage participants with the intervention.

    Methods: We followed the PRECEDE-PROCEED model: regular emollient use was the target behavior we were seeking to promote and we identified potential techniques to influence this. LifeGuide software was used to write the intervention website. Carers of children with eczema were invited through primary care mail-out and randomized to 3 groups: (1) website only, (2) website plus HCP support, or (3) usual care. Patient-Oriented Eczema Measure (POEM) scores were measured online by carer report at baseline and at 12 weeks. Qualitative interviews were carried out with 13 HCPs (primarily practice nurses) and 26 participants to explore their experiences of taking part in the study.

    Results: A total of 143 carers were recruited through 31 practices. We found a decrease of ≥2 in follow-up compared with baseline POEM score in 23 of 42 (55%) participants in the website only group, 16 of 49 (33%) in the usual care group, and 18 of 47 (38%) in the website plus HCP group. Website use data showed that 75 of 93 (81%) participants allocated to the website groups completed the core modules, but less than half used other key components (videos: 35%; regular text reminders: 39%). There were no consistent differences in website use between the website only or the website plus HCP groups. Qualitative feedback showed that most HCPs had initial concerns about providing support for eczema self-care because this was not a condition that they felt expert in. However, HCPs reported productive consultations and that they found it helpful to use the website in consultations, while observing that some participants seemed to need more support than others. Qualitative interviews with participants suggested that HCP support was valued highly only by a minority, generally those who were less confident in their management of eczema or less confident using the Internet.

    Conclusions: Our pilot trial demonstrated the potential for greater improvements in POEM scores in both website intervention groups and that a full-scale trial is feasible. Such a trial would quantify the effectiveness and cost-effectiveness of this intervention to determine whether it should be widely promoted to families of children with newly diagnosed eczema. In this study population, HCP support was not strongly valued by participants and did not lead to better outcomes or website use than use of the Web-based intervention alone.

    Trial Registration: International Standard Randomized Controlled Trial Number (ISRCTN): 98560867; http://www.controlled-trials.com/ISRCTN98560867 (Archived by WebCite at http://www.webcitation.org/6NcxvMtgN).

    J Med Internet Res 2014;16(3):e70)

    doi:10.2196/jmir.3035

    KEYWORDS



    Introduction

    Childhood eczema, or childhood atopic dermatitis, is very common, affecting more than 20% of children aged 5 years or younger at some point [1]. It can cause significant distress to the child and family because of sleep disturbance and itch [2]. The main cause of treatment failure is carers not using treatments correctly due to not understanding treatments, child refusal, or the therapy being too time-consuming [3]. Carers may need support in dealing with behavioral issues, such as scratching and sleep disturbance or children refusing topical treatments.

    A Cochrane review found that most studies of parental education for childhood eczema have been small or of poor quality [4]. The National Institute for Health and Care Excellence (NICE) guideline on eczema in children [5] concluded that lack of education about therapy leads to poor adherence (ie, carers not using creams) and consequently to treatment failure.

    Families of children with eczema express frustration that they do not receive enough support and information about how to manage the condition [6,7]. An Internet-delivered self-management intervention for carers offering information and support about childhood eczema to carers could address this gap. Web-based interventions have been shown to produce small but significant changes in health-related behaviors, particularly where intervention development is based on theory and multiple behavior techniques are incorporated [8]. In terms of patient outcomes, Web-based interventions for diabetes have shown small beneficial effects on blood glucose [9]. Among children and adults referred to secondary care for eczema, an eHealth package (including Internet-guided self-management and Web-based consultations) was found to be just as effective as usual face-to-face dermatology care, but was more cost-effective [10]. Internet-based self-management interventions have been found to lead to improved outcomes in other pediatric long-term illnesses, particularly asthma [11,12].

    The effectiveness of computerized mental health interventions have been shown to be enhanced by health care professional (HCP) support or other social support [13]. A systematic review that included interventions aimed at lifestyle change, mental health, or chronic conditions suggested that increased human support is associated with increased adherence to interventions [14]. However, many of the interventions studied in chronic conditions involved clinic-based HCP support for conditions such as diabetes, arthritis, or chronic pain. It is not clear for which conditions and to what extent HCP support is necessary to engage users with Web-based interventions for chronic illness.

    We developed a Web-based intervention aimed at improving management of childhood eczema by parents/carers. We sought to test the intervention in a pilot trial to investigate feasibility of intervention delivery and to gather preliminary information for a full-scale randomized controlled trial (RCT). We included 3 groups: (1) Web-based intervention plus usual care, (2) Web-based intervention plus HCP support plus usual care, and (3) usual care alone.


    Methods

    Development of Web-Based Intervention

    The home page on the SPaCE (Supporting Parents and Carers of Children with Eczema) website had a link to allow users to access brief information about members of the research team (including University affiliations) and the medical experts who developed the website. Participants then followed 2 short compulsory modules (approximately 20 minutes) on “What is eczema?” and “Emollient moisturizers” before reaching a menu of modules reflecting common concerns of carers of children with eczema. These were identified through previous qualitative interviews and discussion with patient support groups.

    We followed the PRECEDE-PROCEED model [15], using a team approach to identify relevant behaviors amenable to change and potential techniques for addressing these. Details of intervention development are presented in Textbox 1 and an overview of the intervention is given in Textbox 2.

    The intervention included 20 of 26 theory-based behavior change techniques listed in a taxonomy developed to standardize definitions [18] (Table 1). See Figures 1 and 2 for illustrative screenshots of the website. More screenshots are shown in Multimedia Appendix 1.


    Textbox 1. Development of the Web-based intervention for childhood eczema.
    View this box

    Textbox 2. Overview of Web-based intervention for childhood eczema.
    View this box
    Table 1. Behavior change techniques [16] that are incorporated into the SPaCE Web-based intervention.
    View this table
    Figure 1. Screenshot of SPaCE website welcome page.
    View this figure
    Figure 2. Screenshot of SPaCE menu of modules.
    View this figure

    Study Population

    Our intervention was aimed at carers of children with mild or moderate eczema; most of whom were managed in general practice in the United Kingdom. We recruited through a mail-out from 31 general practitioner (GP) practices in South West England, recruiting as many practices as possible from areas of social deprivation because this part of England is generally above average in terms of socioeconomic class. General practices posted invitations to parents/carers of children aged 5 years or younger with eczema. Carers were asked to post a reply to the research team if they wished to participate in the study.

    Inclusion/Exclusion Criteria

    Inclusion criteria included parent/carer of a child aged 5 years or younger with a GP diagnosis of eczema who had obtained a prescription for this in the past year. Exclusion criteria applied by GPs included child aged older than 5 years, known severe mental distress, recent bereavement, opposition to involvement in research, carer unable to give informed consent, or with insufficient English to use website or complete outcome measures. If carers did not wish to take part, they were invited to indicate on the reply slip why this was (see Figure 3). If a family had more than one child meeting eligibility criteria, they were asked to choose one child when answering questionnaire items about their child’s eczema.

    Figure 3. Flow of study participants through trial.
    View this figure

    Pilot Randomized Controlled Trial

    If carers replied that they were interested in participating, they were sent a unique log-in to complete online consent, baseline questionnaires, and randomization. Online randomization was carried out using LifeGuide software allocating participants to 1 of 3 equal groups: (1) usual care plus Web-based intervention, (2) usual care plus Web-based intervention plus HCP support, or (3) usual care.

    Emails were sent 12 weeks later requesting online questionnaire follow-up with 2 email reminders and subsequent phone follow-up for nonresponders requesting responses for core outcome measures.

    Health care professional support was a single appointment aimed at engaging carers with the intervention, rather than teaching them about eczema. In 11 practices this was carried out by a practice nurse, but 1 practice assigned the role to a health care assistant and 1 to a GP. Only one of the practice nurses had specific dermatology training. Health care professionals were asked to spend up to 1 hour familiarizing themselves with the intervention. Participating HCPs were then asked to phone participants to arrange a 20-minute appointment at a convenient time in the first few weeks after randomization. The HCPs were informed that their role was not to deliver eczema care, but to encourage participants to use the website as a resource to help them manage their child’s eczema. They were asked to have the website open during the appointment and to go through the core modules with the participants if they had not already completed them, and to discuss the 2-week challenge if they had not already done this. If they had completed these, the HCPs were asked to allow the participant to choose other modules to go through together.

    Usual care consisted of carers continuing to attend services in the usual way. For most participants this meant making an appointment with their GP when they felt it necessary. A minority were under regular secondary care review by a dermatologist or dermatology nurse.

    Outcome Measures

    Our primary outcome was the Patient-Oriented Eczema Measure (POEM) [19] questionnaire completed online by carers at 12 weeks. This includes 7 questions about eczema symptoms over the previous week which are summed to give a score from 0 (no eczema) to 28 (worst possible eczema). POEM is a patient-reported outcome that can be used by proxy (carer report), is recommended by NICE, and demonstrates good validity, repeatability, and responsiveness to change [20]. Disease-specific quality of life was measured by the Dermatitis Family Impact (DFI) questionnaire, Infants Dermatitis Quality of Life (IDQoL) index, and Children’s Dermatology Life Quality Index (CDLQI). The DFI [21] is a widely used validated instrument that measures the impact of eczema on the family’s quality of life. The IDQoL [22] and CDLQI [2] are validated measures in children aged 4 years or younger and 5 years or older, respectively.

    To explore the effectiveness of the intervention, the pilot study also included questionnaire items to measure adherence (self-reported emollient use) and attitudes that should predict adherence (instrumental and affective attitudes, perceived attitudes of others, and perceived control over adherence). We included the Problematic Experiences of Therapy Scale (PETS), used in previous studies to explore adherence to interventions [23,24]. The PETS asks participants to what extent they have been prevented from carrying out the intervention by socially acceptable reasons for noncompliance (eg, uncertainty about how to carry out treatment, lack of time) before asking about adherence to the intervention and to treatment (emollient use). We also asked participants to complete the Patient Enablement Instrument, which assesses whether they feel they can understand and manage treatment better [25].

    Quantitative Analysis

    A change in POEM score of 3 or more is thought to be clinically significant in a secondary care setting [26]. However, baseline POEM scores in primary care are lower because many children experience mild eczema; therefore, we determined a score change of 2 would likely to be a clinically significant difference. We wished to be able to detect a small difference because the intervention is relatively inexpensive and even small effect sizes are likely to be cost-effective for such a common condition. Differences between groups were examined using chi-square tests. Analyses were carried out on an intention-to-treat basis. Analyses were carried out using SPSS version 21 (IBM Corp, Armonk, NY, USA).

    Qualitative Interviews With Health Care Professionals

    Qualitative interviews were carried out with 13 of 14 HCPs who provided support sessions, but one could not be contacted after repeated attempts. Interviews were carried out by phone by a researcher who was not otherwise involved in the study. The interview guide included general questions about their experiences of participating in the study and detailed questions about the conduct and content of appointments they had had with carers, including what parts of the website they had looked at, problems encountered at any stage, and their impressions of usefulness of the appointment for carers. Interviews were recorded, transcribed, and analyzed thematically.

    Qualitative Interviews With Participants

    Of the 143 parents/carers who took part in the pilot study, 82 agreed to be contacted for a feedback interview. We approached 45 of these after they had completed their follow-up questionnaire, purposively sampling those who had been in the website only or website plus HCP groups, including those who had not attended appointments. We also purposively sampled participants from lower socioeconomic class areas. Of the 45 we approached, 14 were uncontactable after 6 attempts, 4 declined to be interviewed, 1 gave email feedback, and 26 were interviewed. We offered a choice of telephone or face-to-face interview; 10 interviews were carried out by phone, 15 were carried out in participants’ homes, and 1 at a participant’s workplace. Interviews lasted from 20 to 60 minutes and were audio-recorded, transcribed, and analyzed thematically.

    Qualitative Analysis

    Thematic analysis was used to analyze the data [27]. Transcripts were read and reread to allow familiarization with the data. Initial coding was applied by MS then developed iteratively until all important information within the dataset was coded. Coding schedules and themes were further refined through discussion (MS, IM, and LY for HCP interviews; MS, HS, and LY for participant interviews). Coding was applied using NVivo 10 software to facilitate data handling. Pseudonyms have been assigned in reporting the findings.

    Ethics Approval

    Ethical approval for this study was given by the Berkshire Research Ethics Committee (MREC: 10/H0505/56) as a registered randomized controlled trial (ISRCTN 98560867).


    Results

    Recruitment and Participant Characteristics

    A total of 1947 invitation letters were sent from 31 GP practices to parents or carers of children with eczema. We received replies from 458 households (23.52%), with 233 of 1947 (11.97%) replying that they wished to take part in the study. The main reason for not wishing to take part was that their child’s eczema was no longer a problem (186/1947, 9.55%). In all, 149 of 1947 (7.65%) people registered online and were randomized into the trial, but 1 participant did not have usable data because of technical problems and was not included in the analysis. At follow-up, 88 of 143 (61.5%) completed the questionnaire online, 50 (35.0%) completed key questions by phone (POEM, DFI, and questions about adherence to emollient therapy), and 5 (3.5%) were uncontactable. Follow-up questions not asked by phone received response rates below 60%; therefore, they will not be presented here. Figure 3 shows the flow of participants through the study and Table 2 shows participant characteristics.

    Table 2. Participant characteristics.
    View this table

    Intervention Use

    Total time spent on the website ranged from 8 to 253 minutes with a median of 40 minutes (IQR 23-59). Of the 93 participants in the website groups, 75 (81%) completed the core modules. This was completed with relatively few visits, with only 45 of 93 (48%) participants in the website groups visiting 3 times or more. Key components of the intervention were thought to be watching videos and signing up to the 2-week challenge (see Table 1), but only 35% of website users watched 1 or more videos and only 39% signed up for short message service (SMS) text message alerts for the 2-week challenge. There were no consistent differences in website use between the website only and the website plus HCP groups (Table 3).

    Uptake of HCP support for the intervention was lower than expected. Only 23 of 50 (46%) participants who were allocated to the website plus HCP support group actually attended their appointments (12 declined the appointment, 9 participants could not be contacted to arrange an appointment, 6 made an appointment but did not attend).

    Table 3. Intervention use.
    View this table

    Primary Outcome

    Baseline POEM scores were relatively low (mean 9.0, SD 6.6), with POEM scores of 0-2=clear/almost clear, 3-7=mild, 8-16=moderate, 17-24=severe, and 25-28=very severe [28]. All groups showed improvement by 12 weeks (mean 7.8, SD 6.6) (see Table 4). This improvement was greater in the website groups: there was a decrease of 2 or greater in follow-up compared with baseline POEM score in 23 of 42 (55%) participants in the website only group, 16 of 49 (33%) in the usual care group, and 18 of 47 (38%) in the website plus HCP group (P=.09). The mean change in POEM score between baseline and follow-up was 1.56 in the combined website groups and 0.41 in the usual care group (ie, a difference between groups of 1.15, 95% CI –0.81 to 2.3).

    To assess whether the intervention was more effective in those with higher baseline eczema severity, we restricted the analysis to the 96 participants with a baseline POEM score of 5 or more, but found a similar relationship: POEM score decreased by 2 or more in 21 of 30 (70%) participants in the website group, 17 of 35 (49%) in the website plus HCP group, and 13 of 31 (42%) in the usual care group (P=.07).

    We also wished to look at whether duration of eczema diagnosis influenced effectiveness of the intervention, but only 14 of 130 (10.8%) participants who answered this question reported that their child had had eczema for 6 months or less. This subgroup was too small to allow reliable comparisons to be made.

    Table 4. Patient-Oriented Eczema Measure (POEM) and Dermatitis Family Impact (DFI) scores at baseline and at 3-month follow-up.
    View this table

    Secondary Outcomes

    The DFI showed even lower baseline scores than POEM. The mean baseline score in this study was 5.7 (SD 5.6), and mean follow-up DFI was 4.8 (SD 5.1). This score is too low to demonstrate differences between groups because of floor effects.

    Health Care Provider Feedback

    Qualitative interviews were carried out with 13 HCPs, 11 practice nurses, 1 GP, and 1 health care assistant. All were women except for the GP. Our findings centered around the following themes: HCP apprehensions about taking part in the study, HCPs and the self-care support role, and HCP perceptions of the usefulness (or not) of the appointments. HCPs said they were pleased to be involved in a study that gave them the opportunity to provide a self-care support role. However, they did report feeling apprehensive initially about supporting self-care for a condition in which they did not view themselves as expert. Training was viewed as very minimal and some concerns remained after training. After seeing participants, HCPs thought consultations had gone well and felt supported by the website, saying that they liked having it open during consultations and felt this worked well. HCPs observed that some parents seemed to find the HCP session more useful than others and felt their support to be unnecessary in some cases:

    I think my only concern really was that they were going to expect me to know a tremendous amount about eczema, and that I wouldn’t sort of meet their expectations...but that didn’t really happen to be honest, because obviously all of the answers were on the website so they were in front of me as well as them.
    [Geena]
    I thought it was good they could point at, for instance use of steroids, and...discuss it in further detail. So they were able to pick an aspect that was from a third party, which is the website, and then bounce ideas or bounce queries off of me. And I think looking to the future, if people have that knowledge already, that might be something that they would be able to use more effectively in a consultation.
    [William]
    The one lady definitely liked the support, the other lady was sort of a bit like, well I’ve done it, why do I need to come in and talk to you about it?
    [Qadira]

    Participant Feedback

    Two men and 24 women, ages ranging from 24 to 44 years, were interviewed. Five were full-time carers and the remainder were working full-time or part-time in a wide range of occupations. Most parents interviewed were managing mild eczema. They had all been managing their child’s eczema for at least 6 months, but most had been managing it for some years.

    Most people found the website helpful, easy to use, and easy to understand. The benefits they ascribed to website use are shown in Table 5.

    Five of the 26 interviewees said they did not find the website helpful, either because it would have been helpful in the past but that they were confident in managing their child’s eczema now or because their child’s eczema was so mild that it did not feel relevant. However, there were others managing mild or longstanding eczema who still found the website helpful. So, although confidence in self-management appeared to be related to how useful they found SPaCE, duration of diagnosis and severity were not necessarily important.

    Table 5. Qualitative findings from participant interviews about experiences of using SPaCE website.
    View this table

    Feelings About Being Offered Health Care Provider Support

    In the website plus HCP group, 15 of 26 were interviewed, of whom 10 had attended appointments and 1 had discussed her daughter’s eczema by phone with the practice nurse. Of the remaining 4, 1 forgot to attend, 1 did not think she had been contacted by the practice, 1 said that the times offered by the nurse were unsuitable for her, and 1 declined the appointment. Sophie was offered a HCP appointment but did not attend:

    I might have done if he was younger and I was still in the state of, “I don’t know what I’m doing and am I doing it right,” but I think, because I feel like I know how it’s going that I didn’t really need any more help really. I think the website being there put me at ease, where if I’d have had no website and the nurse had rung, I would probably have gone to see her, if you see what I mean, because it was nice to have reassurance.
    [Sophie]

    Kim had a nurse appointment that she forgot to attend:

    I wanted to go and see her and tell her that I want to help the study, but like I didn’t, it sounds really conceited, but I didn’t think I would be told anything I didn’t know. Maybe I would have done, like I did in the modules, but I wasn’t really thinking it was going to be any great difference in what I already know.
    [Kim]

    The 11 interviewees in the website only group were mainly happy with their group allocation, saying that the website was enough or fit with everyday life better than attending a nurse appointment. Only 2 of 11 interviewees said that they would have liked to have been offered an appointment: one offered no reason and the other said it might have made her more enthusiastic about using the website more.

    Experiences of Participants Who Attended Health Care Provider Support Session

    Parents’ views regarding the value of the HCP support varied widely. Of the 10 who attended HCP appointments, 4 said they found the appointment useful (although one of these discussed food allergies rather than eczema), 3 said they did not find it useful, and the remainder were noncommittal about whether they found it useful or not. Reasons parents gave for not valuing the HCP appointment included not really feeling they needed help with eczema management (eg, parents felt confident in managing it) or that they felt confident in obtaining information through the Internet:

    We did go and see a nurse during the trial but she didn’t say anything different to what I already knew anyway, so when we made the appointment and went up to see her I must admit, I did think, “Why am I here?”
    [Charlotte]

    Among the few carers who found the HCP appointment useful, they reported that this had encouraged them to revisit the website or directed them to part of website they had not looked at before (eg, videos) or helped them to feel more confident about consulting in the future (although other participants ascribed this to the website rather than the nurse appointment). One participant had enjoyed her appointment, but had chosen to discuss health problems other than eczema and another valued her appointment because she was provided with emollient samples (although this was not part of the intervention):

    I met with the nurse practitioner at my GP surgery and she went through a couple of things on the website with me and we discussed some things together. So actually it brought me closer to the medical team within my own GP surgery as well, so the website was a bit of a connection...and, you know, it’s kind of-very much a long-term situation with eczema but at least I feel like I know who I can speak to if I need to get advice.
    [Emily]

    Nicole is unusual in our sample in that she did not feel comfortable with the Internet and, therefore, really valued the nurse input:

    To be honest I’m not a massive kind of computer person, I don’t work with computers...So it’s probably more to do with that I’m not really used to using them, I don’t really use computers in my daily life. So I think just going and speaking to the nurse was more helpful to me personally.
    [Nicole]

    Discussion

    Principal Results

    This pilot RCT showed a greater improvement in carer-reported eczema scores in both the website only and website plus HCP groups compared with a usual care group. Although the study was not powered, potentially important changes in outcomes were observed in the hypothesized direction and, although not significant at the 5% level, they were significant at the 10% level. Completion of core modules was good in both the website only and the website plus HCP groups, although uptake of some of the intervention components was low.

    This study showed the feasibility of HCPs using a website to support self-care for eczema within the consultation and that initial concerns about providing support for a condition they were not expert in dissipated after they had tried it. However, among this group of carers it seems that many did not particularly value the HCP support, as evidenced by the low take-up of support session appointments and the qualitative findings.

    Limitations

    Our initial mail-out received a low response rate; therefore, those using the intervention could be unrepresentative of families of children with eczema, possibly with higher health literacy or higher motivation than other families. Our intervention, if shown to be beneficial, is designed for dissemination to families of children newly diagnosed with eczema in primary care. Ideally, we would have carried out opportunistic recruitment of newly diagnosed families, but this would not be feasible in primary care so we recruited by mail-out instead, with the consequence that the intervention was less relevant to some families, probably contributing to the low response rate.

    The relatively low use of some components of the intervention (videos and 2-week challenge) suggests that we need to refine the intervention before further evaluation. Although the intervention was developed carefully and adapted on the basis of initial feedback, complex interventions and trials to examine their efficacy frequently need further iterative development [29].

    We are unable to comment on adherence to the target behavior (emollient use) for this intervention because these findings are extremely difficult to interpret. If eczema is in remission, then twice-daily emollient is adequate, but if there is a flare up, then more frequent application is required. Therefore, increased use of emollient can either be related to better adherence or worse eczema, and decreased use of emollient could mean worse adherence or better eczema. For instance, if a child was no longer bathing in soapy water as a result of the intervention, this could lead to an improvement in eczema and effective self-care could mean that emollient use stays the same or even decreases.

    Comparison With Prior Work

    Other studies have found that human support is important in engaging users with online interventions [14,30], but we did not find that in this study. Unsupported use of Web-based interventions requires a fairly high degree of critical health literacy and motivation (ie, due to high symptom distress) [31]. Qualitative interviewees in our study were predominantly comfortable obtaining information online and often referred to the mildness or severity of eczema as being important in how motivated they were to engage with the website. It may be that there are particular features of the population under study that means they are less likely to value health professional support, such as that they were adults aged 20 to 40 years (so relatively computer literate), that eczema is a condition in which a high degree of self-care is expected [7], and many were looking after relatively mild eczema. It is also possible that participants would have welcomed the support more if they had initiated contact with the HCP themselves, rather than the reverse.

    Conclusions

    We conclude that a full-scale RCT of this Web-based intervention is feasible. The findings presented here suggest that HCP support for this study population might not be necessary; therefore, this will not be included in the RCT. These findings also support keeping the invitation to participate quite broad because some parents caring for mild or longstanding eczema still valued having access to the website (even though it was targeted at the newly diagnosed). The website will be further refined before the next stage of evaluation.

    Acknowledgments

    We would like to thank the parents involved for participating in this research and the practices and Primary Care Research Network for facilitating this. We would like to thank the Centre for Evidence-Based Dermatology and the Nottingham Support Group for Carers of Children with Eczema for help with developing the intervention. This report is independent research arising from a Research for Patient Benefit grant from the National Institute of Health Research PB-PG-0110-20243. The views expressed in this publication are those of the authors and not necessarily those of the NHS, the National Institute of Health Research, or the Department of Health.

    Conflicts of Interest

    None declared.

    Multimedia Appendix 1

    Illustrative screenshots.

    PPTX File, 2MB

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    Abbreviations

    CDLQI: Children’s Dermatology Life Quality Index
    DFI: Dermatitis Family Impact
    GP: general practitioner
    HCP: health care professional
    IDQoL: Infants Dermatitis Quality of Life
    PETS: Problematic Experiences of Therapy Scale
    POEM: Patient-Oriented Eczema Measure
    RCT: randomized controlled trial
    SMS: short message service
    SPaCE: Supporting Parents and Carers of children with Eczema


    Edited by G Eysenbach; submitted 23.10.13; peer-reviewed by H Van Os-Medendorp, T Schopf; comments to author 15.11.13; revised version received 16.01.14; accepted 31.01.14; published 04.03.14

    ©Miriam Santer, Ingrid Muller, Lucy Yardley, Hana Burgess, Hannah Selinger, Beth L Stuart, Paul Little. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 04.03.2014.

    This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.