Published on 09.07.13 in Vol 15, No 7 (2013): July
Effectiveness of Web-Based Self-Disclosure Peer-to-Peer Support for Weight Loss: Randomized Controlled Trial
Background: Obesity is one of the most common public health problems in the industrialized world as a cause of noncommunicable diseases. Although primarily used for one-on-one communication, email is available for uninterrupted support for weight loss, but little is known about the effects of dietitian group counseling for weight control via the Internet.
Objective: We developed a Web-based self-disclosure health support (WSHS) system for weight loss. This study aims to compare the effect of weight change between those using the WSHS and those using the email health support (EHS).
Methods: This study was designed as an open prospective individual randomized controlled trial. Eligible participants were aged 35 to 65 years with a body mass index (BMI) of ≥25.0 in their latest health examination. Participants were randomly assigned to either the WSHS group or the EHS group. Thirteen registered dietitians under the direction of a principal dietitian each instructed 6 to 8 participants from the respective groups. All participants in the WSHS group could receive nutritional advice and calculate their nutritive intake from a photograph of a meal on their computer screen from the Internet sent to them by their dietitian, receive supervision from the registered dietitian, and view fellow participants’ weight changes and lifestyle modifications. In the EHS group, a participant could receive one-on-one nutritional advice and calculate his/her nutritive intake from the photograph of a meal on computer screen sent by email from his/her dietitian, without being able to view fellow participants’ status. The follow-up period was 12 weeks for both groups. The primary outcome measure was change in body weight. The secondary outcome measure included changes in BMI and waist circumference. The intergroup comparison of the changes before and after intervention was evaluated using analysis of covariance.
Results: A total of 193 participants were randomly assigned to either the WSHS group (n=97) or the EHS group (n=96). Ten from the WSHS group and 8 from the EHS group dropped out during the study period, and the remaining 87 in the WSHS group and 88 in the EHS group were followed up completely. Weight loss was significantly greater in the WSHS group than in the EHS group (–1.6 kg vs –0.7 kg; adjusted P=.04). However, there were few differences in waist circumference between the 2 groups. (–3.3 cm vs –3.0 cm; adjusted P=.71).
Conclusions: Our newly developed WSHS system using forced self-disclosure had better short-term weight loss results. Further study in a longer-term trial is necessary to determine what effects this type of intervention might have on long-term cardiovascular disease.
Trial Registration: University Hospital Medical Information Network Clinical Trial Registration (UMIN-CTR): UMIN000009147; https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr.cgi?function=brows&action=brows&type=summary&recptno=R000010719&language=E (Archived by WebCite at http://www.webcitation.org/6HTCkhb1p).
J Med Internet Res 2013;15(7):e136
Obesity is one of the most common public health problems in the industrialized world as a cause of noncommunicable diseases, such as ischemic heart disease and diabetes mellitus [, ]. It has been reported that people are more likely to gain weight when obese persons are around them [ ]. In a similar way, behavior modification for weight loss might also transmit to others if a person makes an effort to lose weight. In addition, the necessity to enhance the motivation for weight loss in nutritional counseling has been emphasized [ ].
In nutritional counseling for weight loss, face-to-face support that takes into consideration the individual’s background and personal characteristics is generally conducted by registered dietitians [, ]. Recently, emails, which are primarily for one-on-one communication, have been used for weight loss [ - ]. Self-disclosure plays a central role in the development and maintenance of relationships [ ], and is also thought to be a critical component in enabling the therapeutic progress [ ]. Although writing about experiences of weight loss through blogging as a means of self-disclosure has expanded rapidly recently [ ], it is unclear whether forced self-disclosure via the Internet would be actually effective for weight loss.
We developed a Web-based self-disclosure health support (WSHS) system through which participants can receive counseling from a registered dietitian and compare their own changes in weight and lifestyle with those of others. This study aimed to compare the weight loss between the WSHS and the email health support (EHS). Our hypothesis is that weight loss would be greater in the WSHS group than in the EHS group.
This study was an open prospective individual randomized controlled trial (UMIN000009147), carried out from July 2008 through February 2009.
For this study, we recruited participants by mail, contacting clients of the Kyoto University Health Service, Japan, urging them to obtain nutritional counseling for weight loss. Men and women aged 35 to 65 years with a body mass index (BMI) of 25.0 kg/m2 or more from their latest health examination were eligible. Persons who agreed to participate in our study were invited to an initial face-to-face guidance interview. At this interview, those who had been receiving dietary and exercise therapies, or who could not access Internet or email, or who had a current BMI less than 24.5 kg/m2 were excluded from our intervention.
At the first guidance interview, we obtained written informed consent and baseline characteristics, such as sex, age, body height and weight, and waist circumference, and established the participants’ own target level of weight loss. In addition, we conducted a baseline questionnaire survey on the participants’ quality of life (QOL) [, ]. QOL was measured using the Medical Outcomes Study Short-Form 36 survey (SF-36) [ , ], which is a self-reported measure that assesses 4 separate QOL domains, including general health perception, vitality, role of functioning related to physical and emotional problems, and mental health. Higher scores indicate a more positive health-related QOL for each item [ , ].
The participants were randomly assigned to either the WSHS group or the EHS group using the minimization method, balancing sex (male or female), age (<40 years or ≥40 years), and baseline body weight (<60 kg, 60-80 kg, or ≥80 kg) by 1 of the authors (MA). Then they were assigned a counselor-dietitian. A total of 13 registered dietitians under the direction of a principal dietitian provided nutritional counseling. Each dietitian was allocated to both 1 of the WSHS groups and 1 of the EHS groups to minimize the intergroup differences in dietitians’ counseling, with 6 to 8 participants of a group being supported by 1 assigned dietitian during the study period. Each dietitian uniformly counseled the participants in both groups based on the standardized manual on the nutritional values of diet records and a photograph of a meal  provided by the principal dietitian to maintain the homogeneity of guidance among dietitian counselors. The follow-up period was 12 weeks for both groups.
Interventions and Follow-up
The WSHS group members were given a personal account and password, and could freely access the WSHS system (). Each participant set his/her own username and target body weight at the beginning. All members were requested to fill in their present body weight and the level of their lifestyle modification attained such as food records and exercise, along with their motivation level, which were expressed in a 3-level scale (good, fair, and poor), on the screen of the individual’s system Web page every week. Participants received nutritional advice and had their nutritive intakes calculated by their dietitians using a photograph of a meal. A participant and his/her dietitian could discuss their questions and comments in this personal area. In this system, group members could view their fellow participants’ weight changes (not actual values) and their related conditions. A participant and his/her dietitian could put their queries or comments on the participant’s individual screen, but fellow participants could not write in this column.
The EHS group members were provided with a Microsoft Excel file. They set their target body weight loss at the beginning, and subsequently filled in their present body weight, their levels of lifestyle modification attainment, and their motivation level, similar to the WSHS group members. They could send questions and receive nutritional advice and photo-based nutritive intakes by email. However, the EHS was not a Web-based system, and the participants could not obtain information on their fellow participants’ health status via the Web.
The difference between the 2 interventions was that WSHS participants could receive advice from the corresponding dietitian and view other participant’s progress when they accessed this system, and EHS participants could only receive advice from the corresponding dietitian. After 12 weeks of online health support, the participants were asked to come in for remeasurement of their height, weight, waist circumference, and QOL by the same dietitian they saw at the beginning of the study.
The primary outcome measure was change in body weight. The secondary outcome measure included changes in BMI, waist circumference, and QOL.
The sample size was calculated based on weight loss during the 12 weeks. We hypothesized that participants assigned to the WSHS group would lose a mean of 2.0 kg after the 12-week intervention, compared with a loss of 1.0 kg in the EHS group with standard deviations of 2.0 kg for both groups [- ]. Based on 0.9 power to detect a significant difference (P=.05, 2-sided), 85 participants were required for each study group. To compensate for possible absences, we enrolled 90 participants per group.
We conducted intention-to-treat analyses in this study. All data are expressed as mean (SD). BMI was calculated as weight/height2. Baseline characteristics were compared between the groups using unpaired Student t test for numerical variables and Pearson chi-square test for categorical variables. The comparison of changes before and after intervention between the groups was evaluated using analysis of covariance adjusted for sex, age, and the baseline value of the corresponding item at the first guidance interview. All statistical analyses were performed using JMP 9 statistical software (SAS Institute, Inc, Cary, NC, USA). All tests were 2-tailed and P values of <.05 were considered statistically significant.
All procedures were conducted according to the Declaration of Helsinki. Participants submitted their written informed consent before participation. This study was approved by the Ethics Committee of Kyoto University Graduate School of Medicine.
A total of 196 participants were recruited for this trial from July 2008 through February 2009. Among them, 3 participants with a BMI of <24.5 at the first guidance interview were excluded, and the remaining 193 were randomly assigned to either the WSHS group (97) or the EHS group (96). Ten persons from the WSHS group and 8 from the EHS group dropped out during the study period, leaving 87 in the WSHS group and 88 in the EHS group to complete the study ().
Baseline characteristics of the participants are shown in. Mean age was 50 years (SD 7), and mean body weight was approximately 78 kg (SD 10) in both groups. There were no significant differences in sex ratio, BMI, waist circumference, target body weight loss, or QOL levels between the groups.
Differences in changes of outcomes between the WSHS group and EHS group are shown in. The loss in body weight was significantly greater in the WSHS group than in the EHS group (–1.6 kg versus –0.7 kg; adjusted P=.04). The decrease in BMI tended to be also greater in the WSHS group than in the EHS group (–0.6 versus –0.3; adjusted P=.05) although it was statistically insignificant. There were no significantly different changes in waist circumference. Changes in QOL scores, general health perception, vitality, role functioning related to physical and emotional problems, and mental health were not significantly different between the groups.
|Participants’ characteristics||Web-based self-disclosure health support (n=97)||Email health support (n=96)||P value|
|Male, n (%)||84 (86.6)||82 (85.4)||.81a|
|Age (years), mean (SD)||50.7 (7.4)||49.6 (7.2)||.31b|
|Physical characteristics, mean (SD)|
|Body weight (kg)||78.8 (10.6)||77.1 (9.6)||.23b|
|Body mass index (kg/m2)||27.5 (3.1)||27.4 (2.5)||.28b|
|Waist circumference (cm)||94.9 (7.2)||93.6 (7.2)||.26b|
|Target weight loss (kg)||–4.5 (1.7)||–4.5 (1.9)||.95b|
|Quality of life from SF-36,cmean (SD)|
|General health perception||52.1 (17.3)||52.7 (13.9)||.79b|
|Vitality||55.0 (15.9)||55.4 (16.3)||.86b|
|Role functioningd||67.1 (21.3)||69.9 (17.7)||.34b|
|Mental health||66.0 (17.0)||66.2 (14.6)||.93b|
aPearson chi-square test.
bStudent t test.
cData from 86 participants in the Web-based self-disclosure health support group and 88 participants in the email health support group.
dRole functioning: role functioning related to physical and emotional problems.
|Changes in outcomes||Web-based self-disclosure health support (n=87)||Email health support (n=88)||P valuea|
|Physical changes mean (SD)|
|Body weight (kg)||–1.6 (2.7)||–0.7 (2.3)||.02||.04|
|Body mass index (kg/m2)||–0.6 (1.0)||–0.3 (0.8)||.03||.05|
|Waist circumference (cm)||–3.3 (3.3)||–3.0 (3.9)||.64||.71|
|Changes in items on quality of life from SF-36,cmean (SD)|
|General health perception||0.4 (13.3)||–1.4 (11.5)||.44||.36|
|Vitality||0.0 (13.3)||–0.6 (13.3)||.80||.98|
|Role functioningd||4.0 (26.1)||4.7 (19.1)||.89||.70|
|Mental health||0.5 (17.1)||1.1 (11.1)||.82||.66|
aAnalysis of covariance.
bP values were adjusted for sex, age, and the baseline value of the corresponding item at the first guidance interview.
cData from 57 participants in the Web-based self-disclosure health support system group and 59 participants in the email health support group were acquired.
dRole functioning: role functioning related to physical and emotional problems.
We developed the WSHS system, which is capable of activating self-disclosure, and evaluated its effectiveness in controlling body weight in a randomized controlled trial. In this trial, the WSHS yielded participants with a significantly greater weight loss than did the EHS. Although previous studies developed and evaluated weight loss applications [- ], our WSHS system is a first step in exploring the benefits of a system in which there is forced self-disclosure and helpful information on nutritional counseling.
It is well-known that face-to-face counseling is effective for weight loss and blood sugar control [, ]. However, it would be exceedingly difficult to continue face-to-face support for busy middle-aged workers who are candidates for cardiovascular diseases [ , ]. Here, Internet health care support, including email counseling, has shown itself to be similarly effective as the face-to-face method [ - ]. Because Internet services, including e-learning, are useful [ , ], our WSHS system can also be a useful tool for people who need health support. In addition, the beneficial effects of self-disclosure in health care counseling should be emphasized [ ]. The participants were fully aware of their fellow participants’ health status, which might have encouraged them to attain their own health goals.
Although reduction in body weight was significantly greater in the WSHS group than in the EHS group, there were no significant differences in waist circumference between the groups. Intra-abdominal fat accumulation of 100 cm2 or more is one of the cardiovascular risk factors . An 85-cm waist circumference corresponds to approximately 100 cm2 of intra-abdominal fat accumulation, and is used as a simple diagnostic criterion of metabolic syndrome in Japan [ ]. It is known that the measurement of waist circumference varies with participants’ intention to flatten their stomach [ ], and this flattening might have affected the evaluation of waist circumference in this study.
This study also evaluated 4 SF-36 items as weight loss-associated QOL, but there were few differences in the changes between groups. In previous studies, QOL in obese persons was lower because they were more likely to have low back pain, joint disorders, sleep disorders, and depression [- ]. Patients with metabolic syndrome were also more likely to be depressive [ ]. Furthermore, persons who had succeeded in weight loss improved their own general perception of health and physical functioning [ , ]. The short length of our study or the small intergroup difference in weight loss might have blurred the effects on QOL. Further investigation is needed to evaluate whether WSHS will lead to greater QOL [ ]. The number of Internet users reached approximately 2.3 billion people in 2012 across the globe [ ]. Therefore, nutritional counseling via the Internet can reach more people and offer more continuous professional support [ ]. The WSHS system might cost more to produce than the EHS system; therefore, the cost-effectiveness is an important issue that should be discussed in the future. However, the WSHS systems using forced self-disclosure could be a promising means for decreasing the current high rates of obesity.
This study has some inherent limitations. First, the WSHS system is limited to those who can use a personal computer. Second, we only observed the effect on weight loss. The true endpoint of nutritional counseling should be the reduction in mortality and morbidity from cardiovascular diseases. Weight loss could prevent cardiovascular events . Therefore, we consider that weight change is reasonable as a short-term index. Third, lack of information on the number of interactions over the computer/Web interface over the study period and the dietitian interaction with each participant was another limitation because their differences might influence the difference in weight loss among participants. Fourth, information was lacking on social influence on participants’ behaviors, which might also have a possible effect on the change of weight loss. Finally, although weight change has been commonly used as a reasonable short-term index, the short observation period of this study is another important limitation because obesity is a chronic condition and requires long-term solutions.
Our newly developed WSHS system using forced self-disclosure would be significantly more effective than the EHS system for short-term weight loss. A longer-term trial that further explores the theoretical differences between these 2 interventions would be necessary to draw conclusions about the WSHS effect on longer-term health conditions.
We gratefully acknowledge the generous cooperation of Keiko Ueyama, Yukiyo Matsuoka, Ayumi Okada, Tomoko Kitamura, Masumi Hinatsu, and other allied registered dietitians for their crucially helpful support with their dietetical specialties. We are also deeply indebted to the faculty of Kyoto University School of Public Health for their valuable comments concerning design and data analyses, which were critical for the success of the study. Our thanks also to Yoshimitsu Takahashi, PhD, for his generous support.
Conflicts of Interest
Multimedia Appendix 1
CONSORT-EHEALTH checklist V1.6.2 . jmir_v15i7e136_app1.pdf, 1001KB
- Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA 2012 Feb 1;307(5):491-497. [CrossRef] [Medline]
- Must A, Spadano J, Coakley EH, Field AE, Colditz G, Dietz WH. The disease burden associated with overweight and obesity. JAMA 1999 Oct 27;282(16):1523-1529. [Medline]
- Christakis NA, Fowler JH. The spread of obesity in a large social network over 32 years. N Engl J Med 2007 Jul 26;357(4):370-379. [CrossRef] [Medline]
- Ministry of Health, Labour and Welfare, Health Service Bureau. Ministry of Health, Labour and Welfare. Program concerning standard specific health diagnosis and health guidance (final version) [in Japanese] URL: http://www.mhlw.go.jp/bunya/kenkou/seikatsu/pdf/02.pdf [accessed 2012-08-20] [WebCite Cache]
- Dalle Grave R, Calugi S, Centis E, Marzocchi R, El Ghoch M, Marchesini G. Lifestyle modification in the management of the metabolic syndrome: achievements and challenges. Diabetes Metab Syndr Obes 2010;3:373-385 [FREE Full text] [CrossRef] [Medline]
- Anderson JW, Reynolds LR, Bush HM, Rinsky JL, Washnock C. Effect of a behavioral/nutritional intervention program on weight loss in obese adults: a randomized controlled trial. Postgrad Med 2011 Sep;123(5):205-213. [CrossRef] [Medline]
- Tate DF, Jackvony EH, Wing RR. Effects of Internet behavioral counseling on weight loss in adults at risk for type 2 diabetes: a randomized trial. JAMA 2003 Apr 9;289(14):1833-1836. [CrossRef] [Medline]
- Tate DF, Wing RR, Winett RA. Using Internet technology to deliver a behavioral weight loss program. JAMA 2001 Mar 7;285(9):1172-1177. [Medline]
- Collins CE, Morgan PJ, Jones P, Fletcher K, Martin J, Aguiar EJ, et al. Evaluation of a commercial web-based weight loss and weight loss maintenance program in overweight and obese adults: a randomized controlled trial. BMC Public Health 2010;10:669 [FREE Full text] [CrossRef] [Medline]
- Tate DF, Jackvony EH, Wing RR. A randomized trial comparing human e-mail counseling, computer-automated tailored counseling, and no counseling in an Internet weight loss program. Arch Intern Med 2006;166(15):1620-1625. [CrossRef] [Medline]
- Harvey-Berino J, Pintauro S, Buzzell P, Gold EC. Effect of internet support on the long-term maintenance of weight loss. Obes Res 2004 Feb;12(2):320-329. [CrossRef] [Medline]
- Appel LJ, Clark JM, Yeh HC, Wang NY, Coughlin JW, Daumit G, et al. Comparative effectiveness of weight-loss interventions in clinical practice. N Engl J Med 2011 Nov 24;365(21):1959-1968. [CrossRef] [Medline]
- Collins NL, Miller LC. Self-disclosure and liking: a meta-analytic review. Psychol Bull 1994 Nov;116(3):457-475. [Medline]
- Chaudoir SR, Fisher JD. The disclosure processes model: understanding disclosure decision making and postdisclosure outcomes among people living with a concealable stigmatized identity. Psychol Bull 2010 Mar;136(2):236-256 [FREE Full text] [CrossRef] [Medline]
- Leggatt-Cook C, Chamberlain K. Blogging for weight loss: personal accountability, writing selves, and the weight-loss blogosphere. Sociol Health Illn 2012 Sep;34(7):963-977. [CrossRef] [Medline]
- Ware J, Kosinski M, Dewey J. How to Score Version 2 of the SF-36 Health Survey (Standard & Acute Forms). Lincoln, RI: Quality Metric Incorporated; 2001.
- Fukuhara S, Suzukamo Y. Manual of the SF-36v2 [in Japanese]. Kyoto, Japan: Institute for Health Outcomes & Process Evaluation Research; 2004.
- Japan Diabetes Society. Food exchange list for diabetic diet therapy 6th edition [in Japanese]. Tokyo, Japan: Japan Diabetes Society; Jul 14, 2012.
- Committee diagnostic criteria for metabolic syndrome. Definition and diagnostic criteria of metabolic syndrome [in Japanese]. The Journal of the Japanese Society of Internal Medicine 2005;95(4):188-203 http://www.webcitation.org/6HUPn4D81 [FREE Full text] [WebCite Cache]
- The Japan Society for the Study of Obesity. Committee to create guidelines for obesity treatment. In: 2006 Guidelines for Treatment of Obesity [in Japanese]. Tokyo, Japan: The Japan Society for the Study of Obesity; Apr 15, 2006.
- Utsugi S, Nagata J, Sato K, Ishizuka K, Kubota A. Effects of a weight loss program that set the behavioral goals to reduce body weight based on the target consumption energy [in Japanese]. URL: http://www.dietitian.or.jp/jdainfo/report/pdf/55-3jissenjirei.pdf [accessed 2012-08-20] [WebCite Cache]
- Richardson CR, Buis LR, Janney AW, Goodrich DE, Sen A, Hess ML, et al. An online community improves adherence in an internet-mediated walking program. Part 1: results of a randomized controlled trial. J Med Internet Res 2010;12(4):e71 [FREE Full text] [CrossRef] [Medline]
- Anderson-Bill ES, Winett RA, Wojcik JR. Social cognitive determinants of nutrition and physical activity among web-health users enrolling in an online intervention: the influence of social support, self-efficacy, outcome expectations, and self-regulation. J Med Internet Res 2011;13(1):e28 [FREE Full text] [CrossRef] [Medline]
- van Genugten L, van Empelen P, Boon B, Borsboom G, Visscher T, Oenema A. Results from an online computer-tailored weight management intervention for overweight adults: randomized controlled trial. J Med Internet Res 2012;14(2):e44 [FREE Full text] [CrossRef] [Medline]
- Moore TJ, Alsabeeh N, Apovian CM, Murphy MC, Coffman GA, Cullum-Dugan D, et al. Weight, blood pressure, and dietary benefits after 12 months of a Web-based Nutrition Education Program (DASH for health): longitudinal observational study. J Med Internet Res 2008;10(4):e52 [FREE Full text] [CrossRef] [Medline]
- Tanaka M, Adachi Y, Adachi K, Sato C. Effects of a non-face-to-face behavioral weight-control program among Japanese overweight males: a randomized controlled trial. Int J Behav Med 2010 Mar;17(1):17-24. [CrossRef] [Medline]
- Hiuge-Shimizu A, Kishida K, Funahashi T, Ishizaka Y, Oka R, Okada M, et al. Absolute value of visceral fat area measured on computed tomography scans and obesity-related cardiovascular risk factors in large-scale Japanese general population (the VACATION-J study). Ann Med 2012 Feb;44(1):82-92. [CrossRef] [Medline]
- Examination Committee of Criteria for Obesity Disease in Japan, Japan Society for the Study of Obesity. New criteria for "obesity disease" in Japan. Circ J 2002 Nov;66(11):987-992 http://www.webcitation.org/6HU1rAFuw [FREE Full text] [WebCite Cache]
- Imafuku Y. Evaluation of the Measurement of Waist Circumference [in Japanese]. The Official Journal of the Japanese Society of Laboratory Medicine 2007;55(12):1097-1102.
- Livingston EH, Ko CY. Use of the health and activities limitation index as a measure of quality of life in obesity. Obes Res 2002 Aug;10(8):824-832. [CrossRef] [Medline]
- Kushner RF, Foster GD. Obesity and quality of life. Nutrition 2000 Oct;16(10):947-952. [Medline]
- Vetter ML, Wadden TA, Lavenberg J, Moore RH, Volger S, Perez JL, et al. Relation of health-related quality of life to metabolic syndrome, obesity, depression and comorbid illnesses. Int J Obes (Lond) 2011 Aug;35(8):1087-1094 [FREE Full text] [CrossRef] [Medline]
- Samper-Ternent R, Al Snih S. Obesity in Older Adults: Epidemiology and Implications for Disability and Disease. Rev Clin Gerontol 2012 Feb 1;22(1):10-34 [FREE Full text] [Medline]
- Patrick DL, Skalicky AM, Edwards TC, Kuniyuki A, Morales LS, Leng M, et al. Weight loss and changes in generic and weight-specific quality of life in obese adolescents. Qual Life Res 2011 Aug;20(6):961-968. [CrossRef] [Medline]
- D'Hondt M, Vanneste S, Pottel H, Devriendt D, Van Rooy F, Vansteenkiste F. Laparoscopic sleeve gastrectomy as a single-stage procedure for the treatment of morbid obesity and the resulting quality of life, resolution of comorbidities, food tolerance, and 6-year weight loss. Surg Endosc 2011 Aug;25(8):2498-2504. [CrossRef] [Medline]
- Internet World Stats. Internet users in the world URL: http://www.internetworldstats.com/stats.htm [accessed 2012-08-20] [WebCite Cache]
- Stevens VJ, Funk KL, Brantley PJ, Erlinger TP, Myers VH, Champagne CM, et al. Design and implementation of an interactive website to support long-term maintenance of weight loss. J Med Internet Res 2008;10(1):e1 [FREE Full text] [CrossRef] [Medline]
- Goodpaster BH, Delany JP, Otto AD, Kuller L, Vockley J, South-Paul JE, et al. Effects of diet and physical activity interventions on weight loss and cardiometabolic risk factors in severely obese adults: a randomized trial. JAMA 2010 Oct 27;304(16):1795-1802 [FREE Full text] [CrossRef] [Medline]
- Eysenbach G, CONSORT-EHEALTH Group. CONSORT-EHEALTH: improving and standardizing evaluation reports of Web-based and mobile health interventions. J Med Internet Res 2011;13(4):e126 [FREE Full text] [CrossRef] [Medline]
|BMI: body mass index|
|EHS: email health support|
|QOL: quality of life|
|WSHS: Web-based self-disclosure health support|
Edited by G Eysenbach; submitted 22.10.12; peer-reviewed by K Funk, S Langrial, P Gardiner; comments to author 14.11.12; revised version received 27.12.12; accepted 08.05.13; published 09.07.13
©Mie Imanaka, Masahiko Ando, Tetsuhisa Kitamura, Takashi Kawamura. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 09.07.2013.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.