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Development of a GPT-4–Powered Virtual Simulated Patient and Communication Training Platform for Medical Students to Practice Discussing Abnormal Mammogram Results With Patients: Multiphase Study

Development of a GPT-4–Powered Virtual Simulated Patient and Communication Training Platform for Medical Students to Practice Discussing Abnormal Mammogram Results With Patients: Multiphase Study

The study team reviewed the initial prompt, tested the AI feedback agent by having conversations with the VSP, and worked with the designer to amend the prompt and address unexpected behaviors or technical challenges as they arose. To provide context to the AI debriefing agent, the designer prompted the agent to play the role of an experienced clinician and educator: You are an expert physician with years of experience and a clinical educator at the hospital simulation center.

Dan Weisman, Alanna Sugarman, Yue Ming Huang, Lillian Gelberg, Patricia A Ganz, Warren Scott Comulada

JMIR Form Res 2025;9:e65670

Enhancing Doctor-Patient Shared Decision-Making: Design of a Novel Collaborative Decision Description Language

Enhancing Doctor-Patient Shared Decision-Making: Design of a Novel Collaborative Decision Description Language

“Agenti() ⇒ Agentj()” or “Agenti() ⇐ Agentj()”: Indicates that the message is being passed to another agent. A message declaration needs to be specified on the sender side and a rule declaration on the receiver side. “then”: Indicates that the clause before it must continue the clause after it.

XiaoRui Guo, Liang Xiao, Xinyu Liu, Jianxia Chen, Zefang Tong, Ziji Liu

J Med Internet Res 2025;27:e55341

A Relational Agent Intervention for Adolescents Seeking Mental Health Treatment: Protocol for a Randomized Controlled Trial

A Relational Agent Intervention for Adolescents Seeking Mental Health Treatment: Protocol for a Randomized Controlled Trial

This may be particularly advantageous in adolescent MH interventions, as this group is well-versed in conversational agent and texting interactions [19]. Such interactions may improve users’ treatment responsiveness to interventions [20,21]. Woebot for Adolescents (W-Gen ZD) is an investigational mobile app with a relational agent, “Woebot,” that offers a CBT-guided self-help program designed to reduce symptoms of depression and/or anxiety.

Emil Chiauzzi, Athena Robinson, Kate Martin, Carl Petersen, Nicole Wells, Andre Williams, Mary Margaret Gleason

JMIR Res Protoc 2023;12:e44940

The Impact of a Place-Tailored Digital Health App Promoting Exercise Classes on African American Women’s Physical Activity and Obesity: Simulation Study

The Impact of a Place-Tailored Digital Health App Promoting Exercise Classes on African American Women’s Physical Activity and Obesity: Simulation Study

Therefore, we further developed our agent-based simulation model of Washington, DC to test the impact of such a place-tailored digital health app. All authors’ institutions were included in the institutional review board approval (IRB #00004203) at Johns Hopkins as the study began while certain members of the research team (MCF, KJO, YA, MM, SMB, PTW, SS, SR, MSG, MD, KR, DH, RS, and BYL) were based at Johns Hopkins.

Tiffany M Powell-Wiley, Marie F Martinez, Kosuke Tamura, Sam J Neally, Kelly J O'Shea, Kaveri Curlin, Yardley Albarracin, Nithya P Vijayakumar, Matthew Morgan, Erika Ortiz-Chaparro, Sarah M Bartsch, Foster Osei Baah, Patrick T Wedlock, Lola R Ortiz-Whittingham, Sheryl Scannell, Kameswari A Potharaju, Samuel Randall, Mario Solano Gonzales, Molly Domino, Kushi Ranganath, Daniel Hertenstein, Rafay Syed, Colleen Weatherwax, Bruce Y Lee

J Med Internet Res 2022;24(8):e30581

Interactive Versus Static Decision Support Tools for COVID-19: Randomized Controlled Trial

Interactive Versus Static Decision Support Tools for COVID-19: Randomized Controlled Trial

The other tool was implemented as a simple, interactive conversational agent, where participants clicked buttons to respond to questions, guiding them through the nodes of the decision tree step-by-step (Multimedia Appendix 2). The individual screens of the interactive DST were also designed using Microsoft Power Point and then linked together using In Vision [30], enabling dynamic interaction.

Alice Röbbelen, Malte L Schmieding, Marvin Kopka, Felix Balzer, Markus A Feufel

JMIR Public Health Surveill 2022;8(4):e33733

Digital Behavior Change Interventions for the Prevention and Management of Type 2 Diabetes: Systematic Market Analysis

Digital Behavior Change Interventions for the Prevention and Management of Type 2 Diabetes: Systematic Market Analysis

Intervention delivery characteristics of the companies’ digital behavior change interventions. a DBCI: digital behavior change intervention. b HHP: human health professional. c CA: conversational agent. d—app not accessible. e Hb A1c: glycated hemoglobin A1c. f GPS: Global Positioning System. g INR: Indian Rupee. h CHF: Swiss Franc. The findings regarding the usage of self-reports as well as sensor and device analytics are summarized in Figure 2.

Roman Keller, Sven Hartmann, Gisbert Wilhelm Teepe, Kim-Morgaine Lohse, Aishah Alattas, Lorainne Tudor Car, Falk Müller-Riemenschneider, Florian von Wangenheim, Jacqueline Louise Mair, Tobias Kowatsch

J Med Internet Res 2022;24(1):e33348

An Agent-Based Model of the Local Spread of SARS-CoV-2: Modeling Study

An Agent-Based Model of the Local Spread of SARS-CoV-2: Modeling Study

Agent-based models (ABMs) are a class of computational models based on computer simulations of actions and interactions of autonomous agents, aimed at evaluating how these actions affect the system as a whole. The agent-based approach emphasizes the importance of learning through the agent-environment interaction. This approach is part of a recent trend in the computational models of learning toward developing new ways of studying autonomous organisms in virtual or real environments.

Alessio Staffini, Akiko Kishi Svensson, Ung-Il Chung, Thomas Svensson

JMIR Med Inform 2021;9(4):e24192

Smartphone-Based Virtual Agents to Help Individuals With Sleep Concerns During COVID-19 Confinement: Feasibility Study

Smartphone-Based Virtual Agents to Help Individuals With Sleep Concerns During COVID-19 Confinement: Feasibility Study

We hypothesized that a virtual agent made available via a smartphone app would be efficient and acceptable not only in providing autonomous screening for insomnia complaints but also in establishing digital behavioral interventions to help the population during the COVID-19 crisis. Therefore, to test our hypothesis, we launched a proof-of-concept study during the COVID-19 confinement.  

Pierre Philip, Lucile Dupuy, Charles M Morin, Etienne de Sevin, Stéphanie Bioulac, Jacques Taillard, Fuschia Serre, Marc Auriacombe, Jean-Arthur Micoulaud-Franchi

J Med Internet Res 2020;22(12):e24268