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Effectiveness of Self-Training With a Web-Based Digital Health Application Versus Physiotherapy in the Treatment of Disorders of the Patella: Randomized Controlled Trial

Effectiveness of Self-Training With a Web-Based Digital Health Application Versus Physiotherapy in the Treatment of Disorders of the Patella: Randomized Controlled Trial

This RCT is the first among the 11 RCTs to complete the treatment of the prespecified number of patients. At the time of writing this manuscript, the 10 remaining RCTs are still in the stage of data collection. In this work, different strategies for treating diseases of the patella (ICD-10 M22) were compared between an active control group (CG) that received the current standard therapy in Germany (CG SHI-PT) and an intervention group (IG) using the DHA Mawendo (IG DHA).

Tobias A Mayer, Daniel Koska, Ann-Kathrin Harsch, Christian Maiwald

J Med Internet Res 2025;27:e66463

Improving Diet Quality of People Living With Obesity by Building Effective Dietetic Service Delivery Using Technology in a Primary Health Care Setting: Protocol for a Randomized Controlled Trial

Improving Diet Quality of People Living With Obesity by Building Effective Dietetic Service Delivery Using Technology in a Primary Health Care Setting: Protocol for a Randomized Controlled Trial

The chat2 (Connecting Health and Technology 2) study is a 1-year randomized controlled trial (RCT). Consenting participants will be randomly assigned (1:1) to an intervention or minimal intervention control group. Figure 1 shows the CONSORT (Consolidated Standards of Reporting Trials) study design. Assessments will occur at 0, 6, and 12 months with the primary outcome assessed at 12 months. Study design with randomization to two groups: intervention and control groups.

Deborah A Kerr, Clare E Collins, Andrea Begley, Barbara Mullan, Satvinder S Dhaliwal, Claire E Pulker, Fengqing Zhu, Marie Fialkowski, Richard L Prince, Richard Norman, Anthony P James, Paul Aveyard, Helen Mitchell, Jacquie Garton-Smith, Megan E Rollo, Chloe Maxwell-Smith, Amira Hassan, Hayley Breare, Lucy M Butcher, Christina M Pollard

JMIR Res Protoc 2025;14:e64735

A Rent Subsidy and Identity Capital Intervention for Youth Exiting Homelessness: Protocol for the Transitioning Youth Out of Homelessness 2.0 Pilot Randomized Controlled Trial

A Rent Subsidy and Identity Capital Intervention for Youth Exiting Homelessness: Protocol for the Transitioning Youth Out of Homelessness 2.0 Pilot Randomized Controlled Trial

In March 2019 (after several months of prestudy collaboration), we began the Transitioning Youth Out of Homelessness (TYOH) study, a 2.5-year pilot community-based mixed method randomized controlled trial (RCT) with youth (mean age 22 years) from 3 cities in the province of Ontario [9]. All participants (n=24) received portable rent subsidies (ie, subsidies not tied to a specific location) for 2 years; 13 were randomly assigned an adult mentor.

Naomi S Thulien, Rowen K Stark, Alexandra Amiri, Alex Abramovich, Alex Akdikmen, Alexandra Carasco, Mardi Daley, Bernice Downey, Oluwapelumi (Pukky) Fambegbe, Tyler Frederick, Stephen W Hwang, Nicole Kozloff, Amanda Noble, Cheryl Pedersen, Marsha Rampersaud, Ruth Rodney, Tadios Tibebu, Rosane Nisenbaum

JMIR Res Protoc 2025;14:e66210

Assessment of an App-Based Sleep Program to Improve Sleep Outcomes in a Clinical Insomnia Population: Randomized Controlled Trial

Assessment of an App-Based Sleep Program to Improve Sleep Outcomes in a Clinical Insomnia Population: Randomized Controlled Trial

However, this research still followed the traditional CBT-I structure (ie, 6 weekly sessions lasting 90-120 minutes) and was not tested in a randomized controlled trial (RCT) [31]. While mindfulness is often incorporated as part of the cognitive component of CBT-I [32], the Headspace Sleep Program positions mindfulness as a foundational approach, introducing it first as a tool for building awareness of sleep habits and patterns.

Walter Staiano, Christine Callahan, Michelle Davis, Leah Tanner, Chelsea Coe, Sarah Kunkle, Ulrich Kirk

JMIR Mhealth Uhealth 2025;13:e68665

A Smartphone App Self-Management Program for Chronic Obstructive Pulmonary Disease: Randomized Controlled Trial of Clinical Outcomes

A Smartphone App Self-Management Program for Chronic Obstructive Pulmonary Disease: Randomized Controlled Trial of Clinical Outcomes

We conducted a single-center, 3-arm parallel pilot randomized controlled trial (RCT) to explore the effect of a smartphone app self-management program on clinical health outcomes in adults with COPD on a longitudinal basis of 12 months. The main components of this self-management program were monthly education, symptom tracking, communication with a health care professional, goal setting, and weekly motivational messages from the app.

Lisa Glynn, Eddie Moloney, Stephen Lane, Emma McNally, Carol Buckley, Margaret McCann, Catherine McCabe

JMIR Mhealth Uhealth 2025;13:e56318