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Multilevel Intervention to Support Tailored and Responsive HIV Pre-Exposure Prophylaxis Care in Rural North Carolina: Protocol for a Randomized Controlled Trial

Multilevel Intervention to Support Tailored and Responsive HIV Pre-Exposure Prophylaxis Care in Rural North Carolina: Protocol for a Randomized Controlled Trial

Screenshots from the Health Mpowerment app—(A) enhanced version of the Health Mpowerment app for the intervention condition and (B) limited version of the Health Mpowerment app for the control condition. PEP: postexposure prophylaxis; Pr EP: pre-exposure prophylaxis. Pr EP navigators will connect with participants immediately following app onboarding.

Sarah E Rutstein, Ella Ferguson, Odai Mansour, Nicole Brown, Jacob B Stocks, Anja Washington, Victoria Mobley, Shannon Dowler, Jessie Edwards, Lisa B Hightow-Weidman, Christopher B Hurt, Brian Pence, Kathryn E Muessig

JMIR Res Protoc 2025;14:e68085