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The Effects of Acupoint Stimulation Combined With Transcutaneous Electrical Nerve Stimulation on Labor Pain: Protocol for a Stepped Wedge Cluster Randomized Controlled Trial

The Effects of Acupoint Stimulation Combined With Transcutaneous Electrical Nerve Stimulation on Labor Pain: Protocol for a Stepped Wedge Cluster Randomized Controlled Trial

After disinfecting the ear with an alcohol swab, the midwife will apply vaccaria seeds with adhesive tape onto the selected acupoints and press them for 1-2 min per side to enhance stimulation. Timing of application: The procedure will be performed at the onset of contractions. The seeds should be pressed for 1-2 min per contraction or as tolerated until placental delivery. Postprocedure care: The seeds can remain in place for up to 1-2 days post delivery to alleviate uterine contraction pain.

Yiyun Gu, Xiaojiao Wang, Chunxiang Zhu, Hui Min, Jialu Zhang, Liping Mao, Hua Gao, Hangyun Sun, Xinli Zhu, Chunyi Gu

JMIR Res Protoc 2025;14:e63050

Effectiveness of Neurofeedback-Assisted and Conventional 6-Week Web-Based Mindfulness Interventions on Mental Health of Chinese Nursing Students: Randomized Controlled Trial

Effectiveness of Neurofeedback-Assisted and Conventional 6-Week Web-Based Mindfulness Interventions on Mental Health of Chinese Nursing Students: Randomized Controlled Trial

Explain the 5 facets of mindfulness and the benefits of mindfulness practice Introduce the application of mindfulness practice in daily life and previous findings of mindfulness-based interventions Mindful eating practice Mindful breathing meditation Introduce the definition and practice methods of mindfulness Explain the importance and methods of mindfulness practice; introduce participants to talk to their bodies, relieve their pressure, and relax themselves Mindful body scan practice 3-min breathing space

Shu Jing, Zhenwei Dai, Xiaoyang Liu, Xuelin Yang, Jinglei Cheng, Tianming Chen, Zihang Feng, Xin Liu, Fenghe Dong, You Xin, Zhuoyan Han, Haiyan Hu, Xiaoyou Su, Chen Wang

J Med Internet Res 2025;27:e71741

Clinical Efficacy and Safety of the Herbal Prescription, HH333, in Preventing Recurrent Stroke in Patients With Ischemic Stroke Induced by Small-Vessel Disease: Protocol for Multicenter, Double-Blind, Randomized, Prospective, Pilot Clinical Trial

Clinical Efficacy and Safety of the Herbal Prescription, HH333, in Preventing Recurrent Stroke in Patients With Ischemic Stroke Induced by Small-Vessel Disease: Protocol for Multicenter, Double-Blind, Randomized, Prospective, Pilot Clinical Trial

An estimated glomerular filtration rate < 60 m L/min/1.73 m2 at screening. Within 24 hours of onset. Patients with Korean National Institutes of Health Stroke Scale (K-NIHSS) score 21 to 42. Pregnant, nurses, or women of childbearing potential who have negative pregnancy test results and have not agreed to use contraception during the study.

Han-Gyul Lee, Seungwon Kwon, Woo-Sang Jung, Sang-Kwan Moon, Cheol-Hyun Kim, Dong-Jun Choi

JMIR Res Protoc 2025;14:e70953