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Exploring the Dilemma of AI Use in Medical Research and Knowledge Synthesis: A Perspective on Deep Research Tools

Exploring the Dilemma of AI Use in Medical Research and Knowledge Synthesis: A Perspective on Deep Research Tools

“Overall, I think Deep Research does produce a good first draft that would probably be readily accepted in a mid-tier journal, but which could be significantly improved with editing and revisions. Perhaps the outputs might improve with better prompts or guidance (eg providing refined outlines and a reference list).”

Ariel Yuhan Ong, David A Merle, Siegfried K Wagner, Pearse A Keane

J Med Internet Res 2025;27:e75666

Bringing Executive Function Testing Online: Assessment Validation Study

Bringing Executive Function Testing Online: Assessment Validation Study

However, the timing varies considerably between the 2 tasks in that Freeze Frame utilizes a variable intertrial interval whereas SART has a consistent intertrial interval. The advantage of a variable time interval is that unlike consistent intertrial intervals, which increases attentional lapses and response anticipations [21], the unpredictable timing of the appearance of each image in Freeze Frame requires a more alert state and enhanced response control [22].

Mouna Attarha, Ana Carolina de Figueiredo Pelegrino, Lydia Ouellet, Sarah-Jane Grant, Etienne de Villers-Sidani, Thomas Van Vleet

JMIR Form Res 2025;9:e75687

The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

The Effect of Maternal Choline Intake on Offspring Cognition in Adolescence: Protocol for a 14-year Follow-Up of a Randomized Controlled Feeding Trial

One such study evaluated the effect of providing pregnant women with either 900 mg/day of a choline supplement or a placebo from week 17 of gestation through birth and found a beneficial effect of the choline supplement on 5-month-old infants’ auditory attentional gating [17].

Sophie A Roth, Angie E Lam, Barbara J Strupp, Richard L Canfield, Elisabeth Anne Larson

JMIR Res Protoc 2025;14:e73508

Patterns of Engagement With the mHealth Component of a Sexual and Reproductive Health Risk Reduction Intervention for Young People With Depression: Latent Trajectory Analysis

Patterns of Engagement With the mHealth Component of a Sexual and Reproductive Health Risk Reduction Intervention for Young People With Depression: Latent Trajectory Analysis

We undertook a secondary analysis of anonymized data collected from June 2021 to September 2023 in a randomized controlled trial of MARSSI versus a breast health podcast (Clinical Trials.gov NCT04798248).

Lydia A Shrier, Carly E Milliren, Brittany Ciriello, Madison M O'Connell, Sion Kim Harris

JMIR Mhealth Uhealth 2025;13:e70219

Data Dashboard Acceptability, Use, and Perceived Effectiveness in Disseminating Local Overdose Data and Resources in a Rural New York State County: A Cross-Sectional Study

Data Dashboard Acceptability, Use, and Perceived Effectiveness in Disseminating Local Overdose Data and Resources in a Rural New York State County: A Cross-Sectional Study

Following the launch of the dashboard, we conducted a cross-sectional study targeting adults older than 18 years who lived or worked in Cayuga County using a 20-question online Qualtrics survey [20]. We conducted 2 phases of participant recruitment, resulting in a convenience sample. During the initial recruitment phase, spanning from May to August 2023, participants were offered a US $10 Amazon gift card as an incentive.

Zhongxuan He, Monika Salvage, Corinna A Noel

Online J Public Health Inform 2025;17:e68977

A Resource-Efficient, High-Dose, Gamified Neurorehabilitation Program for Chronic Stroke at Home: Retrospective Real-World Analysis

A Resource-Efficient, High-Dose, Gamified Neurorehabilitation Program for Chronic Stroke at Home: Retrospective Real-World Analysis

All patients were assigned to a single-arm treatment group involving a high-dose, home-based training program (Figure 1 A–B). For the purposes of this work, we consider a high-dose program to be one that achieves a total dosage above 20 hours scheduled time, as these doses are generally considered to deliver outcomes above the minimum clinically important difference [2,5,29]. Overall, the program goal was to deliver 36 hours of training during the program.

Spencer A Arbuckle, Anna Sophie Knill, Michelle H Chan-Cortés, Gabriela Rozanski, Anastasia Elena Ford, Louis T Derungs, John W Krakauer, Naveed Ejaz, David Putrino, Jenna Tosto-Mancuso, Meret Branscheidt

JMIR Serious Games 2025;13:e69335

Authors’ Response to Peer Review of “Using Electrooculography and Electrodermal Activity During a Cold Pressor Test to Identify Physiological Biomarkers of State Anxiety: Feature-Based Algorithm Development and Validation Study”

Authors’ Response to Peer Review of “Using Electrooculography and Electrodermal Activity During a Cold Pressor Test to Identify Physiological Biomarkers of State Anxiety: Feature-Based Algorithm Development and Validation Study”

Specifically, we now included “In the cold-water trials, participants immersed their hand in a circulating water bath set to a constant temperature of 0-6°C. Participants maintained immersion for approximately 5 minutes or until voluntary withdrawal.” Furthermore, we have removed mention of exercise trials, as they were not used in dataset creation or analysis and are thus not relevant to the study.

Jadelynn Dao, Ruixiao Liu, Sarah Solomon, Samuel Aaron Solomon

JMIRx Med 2025;6:e77440

Using Electrooculography and Electrodermal Activity During a Cold Pressor Test to Identify Physiological Biomarkers of State Anxiety: Feature-Based Algorithm Development and Validation Study

Using Electrooculography and Electrodermal Activity During a Cold Pressor Test to Identify Physiological Biomarkers of State Anxiety: Feature-Based Algorithm Development and Validation Study

Peak detection was performed using the Scipy Signal find_peaks function, identifying peaks with a prominence exceeding 0.1 with a peak width greater than 0.04 seconds [30] (blinks typically last between 0.1 and 0.4 seconds [31], averaging around 0.25 s). To focus on blink-like events, we additionally applied criteria based on established blink characteristics: a maximum peak width of 0.5 seconds and a minimum peak height of 0.05 volts [30].

Jadelynn Dao, Ruixiao Liu, Sarah Solomon, Samuel Aaron Solomon

JMIRx Med 2025;6:e69472

Language Models for Multilabel Document Classification of Surgical Concepts in Exploratory Laparotomy Operative Notes: Algorithm Development Study

Language Models for Multilabel Document Classification of Surgical Concepts in Exploratory Laparotomy Operative Notes: Algorithm Development Study

For this reason, we frame our problem in terms of a multilabel document classification task [6] where operative notes take on a series of binary labels as to whether or not a certain intraoperative finding (eg, bleeding and contamination) or technique (eg, bowel resection, hand-sewn anastomosis, and style of fascial closure) occurred during the case.

Jeremy A Balch, Sasank S Desaraju, Victoria J Nolan, Divya Vellanki, Timothy R Buchanan, Lindsey M Brinkley, Yordan Penev, Ahmet Bilgili, Aashay Patel, Corinne E Chatham, David M Vanderbilt, Rayon Uddin, Azra Bihorac, Philip Efron, Tyler J Loftus, Protiva Rahman, Benjamin Shickel

JMIR Med Inform 2025;13:e71176