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Mobile Therapeutic Attention for Treatment-Resistant Schizophrenia (m-RESIST) Solution for Improving Clinical and Functional Outcomes in Treatment-Resistant Schizophrenia: Prospective, Multicenter Efficacy Study

Mobile Therapeutic Attention for Treatment-Resistant Schizophrenia (m-RESIST) Solution for Improving Clinical and Functional Outcomes in Treatment-Resistant Schizophrenia: Prospective, Multicenter Efficacy Study

Vulnerable populations, such as individuals with schizophrenia, require additional research protections to ensure their privacy and security [43]. A cross-cultural psychological assessment focuses on understanding how a client’s cultural background influences their behavior, emotional state, and psychological needs. A recent review of 2248 studies found that only 57 specifically targeted migrants, refugees, or cultural minorities [58].

Jussi Seppälä, Eva Grasa, Anna Alonso-Solis, Alexandra Roldan-Bejarano, Marianne Haapea, Matti Isohanni, Jouko Miettunen, Johanna Caro Mendivelso, Cari Almazán, Katya Rubinstein, Asaf Caspi, Zolt Unoka, Kinga Farkas, Elisenda Reixach, Jesus Berdun, Judith Usall, Susana Ochoa, Iluminada Corripio, Erika Jääskeläinen, m-Resist Group

JMIR Hum Factors 2025;12:e67659

Machine Learning Model for Predicting Coronary Heart Disease Risk: Development and Validation Using Insights From a Japanese Population–Based Study

Machine Learning Model for Predicting Coronary Heart Disease Risk: Development and Validation Using Insights From a Japanese Population–Based Study

Therefore, this dataset is adequate to answer the research questions. Missing data analysis was conducted, and variables with more than 30% missing values were excluded to enhance model robustness. Missing data were imputed using Multivariate Imputation by Chained Equations. See Multimedia Appendix 1 for details on the percentage of missing data for each variable before imputation.

Thien Vu, Yoshihiro Kokubo, Mai Inoue, Masaki Yamamoto, Attayeb Mohsen, Agustin Martin-Morales, Research Dawadi, Takao Inoue, Jie Ting Tay, Mari Yoshizaki, Naoki Watanabe, Yuki Kuriya, Chisa Matsumoto, Ahmed Arafa, Yoko M Nakao, Yuka Kato, Masayuki Teramoto, Michihiro Araki

JMIR Cardio 2025;9:e68066

Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Because of the different modes of administration of these treatments, each group receives both an injection and oral tablets. The study therefore comprises three arms: (1) a “toxin” group treated with an injection of botulinum toxin and placebo oral baclofen; (2) a “baclofen” group treated with oral baclofen and an injection of placebo botulinum toxin; and (3) a double “placebo” group treated with placebo oral baclofen and an injection of placebo botulinum toxin.

Emmeline Montane, Nabila Brihmat, Camille Cormier, Claire Thalamas, Vanessa Rousseau, Gerard Tap, Xavier De Boissezon, Evelyne Castel-Lacanal, Baclotox Group, Philippe Marque

JMIR Res Protoc 2025;14:e62951

Telehealth Initiative to Enhance Primary Care Access in Brazil (UBS+Digital Project): Multicenter Prospective Study

Telehealth Initiative to Enhance Primary Care Access in Brazil (UBS+Digital Project): Multicenter Prospective Study

Data collection was conducted using the REDCap (Research Electronic Data Capture) database, and all information was anonymously recorded. All data collected and analyzed in this study were fully anonymized prior to use. No personally identifiable information was retained or included in any part of the dataset. The research team implemented strict data management procedures to ensure participant confidentiality throughout the study, in compliance with ethical and legal standards.

Celina de Almeida Lamas, Patrícia Gabriela Santana Alves, Luciano Nader de Araújo, Ana Beatriz de Souza Paes, Ana Claudia Cielo, Luciana Maciel de Almeida Lopes, André Longo Araújo de Melo, Thais Yokoyama, Clarice Pagani Savastano, Paula Gobi Scudeller, Carlos Carvalho, Digital Primary Health Unit HCFMUSP Study Group

J Med Internet Res 2025;27:e68434

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

The purpose of this 1-year feasibility study was to work with a community engagement group to develop and test the implementation of a VR HMD exergaming program for children with special needs at a high school. The overall purpose of this study was to identify a replicable protocol that could be implemented within the daily operations of a high school through the following research questions: How much exercise can students feasibly fit within a school-based program?

Byron Lai, Ashley Wright, Bailey Hutchinson, Larsen Bright, Raven Young, Drew Davis, Sultan Ali Malik, James H Rimmer, Pelham High Community Engagement Group

JMIR Form Res 2025;9:e65801

Disease Prediction Using Machine Learning on Smartphone-Based Eye, Skin, and Voice Data: Scoping Review

Disease Prediction Using Machine Learning on Smartphone-Based Eye, Skin, and Voice Data: Scoping Review

A literature review is a systematic way of collecting studies relevant to a research topic, assessing the methodologies and results of the studies, and making recommendations for improvements if necessary [11]. In the health care domain, the implementation of literature reviews has been considered important for conducting further research and developing guidelines for clinical practice [12].

Research Dawadi, Mai Inoue, Jie Ting Tay, Agustin Martin-Morales, Thien Vu, Michihiro Araki

JMIR AI 2025;4:e59094

Assessment of Health System Readiness and Quality of Dementia Services in Peru: Protocol for a Qualitative Study With Stakeholder Interviews and Documentation Review

Assessment of Health System Readiness and Quality of Dementia Services in Peru: Protocol for a Qualitative Study With Stakeholder Interviews and Documentation Review

Using tracers in health systems research is based on the premise that focusing on carefully selected health problems allows for the identification of weaknesses within the system and facilitates more direct insight of its performance [7,8]. Dementia affects multiple aspects of individual and family well-being, serving as an indicator of multimorbidity in both people with dementia and their carers.

Maria Lazo-Porras, Francisco Jose Tateishi-Serruto, Christopher Butler, María Sofía Cuba-Fuentes, Daniela Rossini-Vilchez, Silvana Perez-Leon, Miriam Lúcar-Flores, J Jaime Miranda, Antonio Bernabe-Ortiz, Francisco Diez-Canseco, Graham Moore, Filipa Landeiro, Maria Kathia Cardenas, Juan Carlos Vera Tudela, Lee White, Rafael A Calvo, William Whiteley, Jemma Hawkins, IMPACT Salud Study Group

JMIR Res Protoc 2025;14:e60296

Patient Experiences With a Mobile Self-Care Solution for Low-Complex Orthopedic Injuries: Mixed Methods Study

Patient Experiences With a Mobile Self-Care Solution for Low-Complex Orthopedic Injuries: Mixed Methods Study

Two independent researchers specialized in qualitative research, not involved in daily clinical practice or the VFC research team, conducted digital semistructured interviews to minimize social-desirability bias. The interviews were held within 6 and 10 weeks post injury to warrant an optimal recall. The interviews were guided by a topic list based on literature, including previously mentioned Bowen feasibility parameters (Multimedia Appendix 4) [8].

Jelle Spierings, Gijs Willinge, Marike Kokke, Sjoerd Repping, Wendela de Lange, Thijs Geerdink, Ruben van Veen, Detlef van der Velde, Carel Goslings, Bas Twigt, Collaboration Group

JMIR Hum Factors 2025;12:e53074