On this page you will find automatically updated links (courtesy of Hubmed RSS) to recently published scholarly articles in other journals dealing with following topics:
Internet and medicine
Internet-based assessment of bowel symptoms and quality of life.
Eur J Gastroenterol Hepatol. 2008 Jun; 20(6): 503-5
Muth ER, Switzer FS
This leading article refers to the paper by Enck P, Kowalski A, Martens U and Klosterhalfen S. Internet-based assessment of bowel symptoms and quality of life. Eur J Gastroenterol Hepatol 2006; 18:1263-1269. We apologise to all concerned for the dissociation between the two papers, which was due to an administrative error.(Table is included in full-text article.)Internet-based questionnaires will, no doubt, continue to gain popularity. Internet presents an attractive medium for the researcher to collect large amounts of data with relatively little
PREDICTOR: A Web-Based Tool for the Prediction of Atomic Structure from Sequence for Double Helical DNA with up to 150 Base Pairs.
In Silico Biol. 2007; 7(6): 595-600
Farwer J, Packer MJ, Hunter CA
We announce the release of a web-based tool for DNA structure prediction (PREDICTOR) which allows the calculation of atomic structures of double-helical DNA with up to 150 Watson-Crick base pairs (http://farwer.staff.shef.ac.uk/ PREDICTOR). The semi-empirical method uses computational chemistry to extrapolate knowledge of sequence-dependent DNA structure contained in the X-ray crystal structure database. The properties of the base stacking interactions are treated theoretically, and an empirical model is used to add the conformational constraints imposed
Effects of sample preparation on stable isotope ratios of carbon and nitrogen in marine invertebrates: implications for food web studies using stable isotopes.
Oecologia. 2008 May 9;
Mateo MA, Serrano O, Serrano L, Michener RH
Trophic ecology has benefitted from the use of stable isotopes for the last three decades. However, during the last 10 years, there has been a growing awareness of the isotopic biases associated with some pre-analytical procedures that can seriously hamper the interpretation of food webs. We have assessed the extent of such biases by: (1) reviewing the literature on the topic, and (2) compiling C and N isotopic values of marine invertebrates reported in the literature with the associated sample preparation protocols. The factors considered were:
Chemists spin a web of data.
Nature. 2008 May 8; 453(7192): 139
Brumfiel G
Affygcqc: a web-based interface to detect outlying genechips with extreme studentized deviate tests.
J Bioinform Comput Biol. 2008 Apr; 6(2): 317-34
Osorio Y Fortéa J, Prina E, Lang T, Milon G, Davory C, Coppée JY, Regnault B
Affymetrix GeneChip((R)) oligonucleotide arrays are dedicated to analyzing gene expression differences across distinct experimental conditions. Data production for such arrays is an elaborate process with many potential sources of variability unrelated to biologically relevant gene expression variations. Therefore, rigorous data quality assessment is fundamental throughout the process for downstream biologically meaningful analyses. We have developed a program named AffyGCQC, which is the acronym
Web papers.
Med Teach. 2008 Mar; 30(2): 220-2
What medical educators need to know about "Web 2.0".
Med Teach. 2008 Mar; 30(2): 164-9
McGee JB, Begg M
"Web 2.0" describes a collection of web-based technologies which share a user-focused approach to design and functionality, where users actively participate in content creation and editing through open collaboration between members of communities of practice. The current generation of students in medical school made Web 2.0 websites such as Facebook and MySpace some of the most popular on the Internet. Medical educators and designers of educational software applications can benefit from understanding and applying Web 2.0 concepts to the curriculum and related websites.
IMGT((R)), the International ImMunoGeneTics Information System((R) )for Immunoinformatics : Methods for Querying IMGT((R)) Databases, Tools, and Web Resources in the Context of Immunoinformatics.
Mol Biotechnol. 2008 May 8;
Lefranc MP
IMGT((R)), the International ImMunoGeneTics information system((R)) ( http://imgt.cines.fr ), was created in 1989 by the Laboratoire d'ImmunoGénétique Moléculaire (LIGM) (Université Montpellier 2 and CNRS) at Montpellier, France, in order to standardize and manage the complexity of immunogenetics data. IMGT((R)) is recognized as the international reference in immunogenetics and immunoinformatics. IMGT((R)) is a high quality integrated knowledge resource, specialized in (i) the immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex (MHC) of human and
DNA hypermethylation and clinicopathological features in breast cancer: the Western New York Exposures and Breast Cancer (WEB) Study.
Breast Cancer Res Treat. 2008 May 8;
Tao MH, Shields PG, Nie J, Millen A, Ambrosone CB, Edge SB, Krishnan SS, Marian C, Xie B, Winston J, Vito D, Trevisan M, Freudenheim JL
Aberrant DNA hypermethylation of gene promoter regions has been increasingly recognized as a common molecular alteration in carcinogenesis. We evaluated the association between major clinicopathological features and hypermethylation of genes in tumors among 803 incidence breast cancer cases from a large population-based case-control study conducted in Western New York State. DNA samples were isolated from archive paraffin embedded tumor tissue and
NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11.
Nucleic Acids Res. 2008 May 7;
Lundegaard C, Lamberth K, Harndahl M, Buus S, Lund O, Nielsen M
NetMHC-3.0 is trained on a large number of quantitative peptide data using both affinity data from the Immune Epitope Database and Analysis Resource (IEDB) and elution data from SYFPEITHI. The method generates high-accuracy predictions of major histocompatibility complex (MHC): peptide binding. The predictions are based on artificial neural networks trained on data from 55 MHC alleles (43 Human and 12 non-human), and position-specific scoring matrices (PSSMs) for additional 67 HLA alleles. As only the MHC class I prediction
eHealth
Introducing ehealth to nursing homes: theoretical analysis of improving resident care.
J Med Syst. 2008 Apr; 32(2): 187-92
Breen GM, Zhang NJ
The purpose of this analysis argues that the technology acceptance model and the theory of task technology fit offer justification for the introduction and integration of ehealth web sites (i.e., WebMd.com) into nursing home care facility operations in the United States and abroad. The driving force behind this study concerns the significant care deficiencies in nursing homes, and how ehealth can ameliorate these conditions. Ehealth has never been a focus of study in nursing homes. Examining logistics relating to nursing homes and their residents may reveal which
An integrated strategy of knowledge application for optimal e-health implementation: A multi method study protocol.
BMC Med Inform Decis Mak. 2008 Apr 24; 8(1): 17
Gagnon MP, Legare F, Fortin JP, Lamothe L, Labrecque M, Duplantie J
ABSTRACT: BACKGROUND: E-health is increasingly valued for supporting: 1) access to quality health care services for all citizens; 2) information flow and exchange; 3) integrated health care services and 4) interprofessional collaboration. Nevertheless, several questions remain on the factors allowing an optimal integration of e-health in health care policies, organisations and practices. An evidence-based integrated strategy would maximise the efficacy and efficiency of e-health implementation. However,
E-health: implementation and evaluation research in Scotland - a scoping exercise.
J Telemed Telecare. 2008; 14(3): 119-21
Clark JS, Mair FS, O'Donnell C, Liu J
We searched the National Research Register (NRR) to identify funded research in Scotland (or in collaboration with a Scottish partner) in the area of implementation and evaluation of e-health services. A total of 61 research projects were identified which had been funded since 1 January 1995. These projects shared almost pound7 million of funding ( pound1 is $1.9 or euro1.3), the main funding sources being the Scottish Government and the European Union. Based on the projects reviewed, the majority of e-health research in Scotland was being
An assessment of technology-based service encounters & network security on the e-health care systems of medical centers in Taiwan.
BMC Health Serv Res. 2008; 8: 87
Chang HH, Chang CS
BACKGROUND: Enhancing service efficiency and quality has always been one of the most important factors to heighten competitiveness in the health care service industry. Thus, how to utilize information technology to reduce work load for staff and expeditiously improve work efficiency and healthcare service quality is presently the top priority for every healthcare institution. In this fast changing modern society, e-health care systems are currently the best possible way to achieve enhanced service efficiency and quality under the restraint of healthcare cost control.
eHealth interoperability.
Stud Health Technol Inform. 2008; 134: 245-53
Hammond WE
For improving quality and safety of patient's care, for keeping the costs of health services, but also for successfully managing public health communication and cooperation between all stakeholders is inevitable. Such interoperability can be provided at different levels from simple data exchange up to business interoperability. The paper introduces those interoperability levels and international standards specifying and facilitating them. In that context, the expression of business requirements by domain analysis models or story boards as well as by functional
Current status of national eHealth and telemedicine development in Finland.
Stud Health Technol Inform. 2008; 134: 199-208
Reponen J, Winblad I, Hämäläinen P
This eHealth paper shows the results of a survey produced by FinnTelemedicum, Centre of Excellence for Telehealth at the University of Oulu and STAKES (National Research and Development Centre for Welfare and Health development in Finland) under assignment of the Finnish Ministry of Social Affairs and Health. The survey shows the status and trends of the usage of eHealth applications in the Finnish health care in 2005. The results are compared to an earlier survey made in 2003. The 2005 survey included all service providers in public and
ICW eHealth Framework.
Stud Health Technol Inform. 2008; 134: 177-90
Klein K, Wolff AC, Ziebold O, Liebscher T
The ICW eHealth Framework (eHF) is a powerful infrastructure and platform for the development of service-oriented solutions in the health care business. It is the culmination of many years of experience of ICW in the development and use of in-house health care solutions and represents the foundation of ICW product developments based on the Java Enterprise Edition (Java EE). The ICW eHealth Framework has been leveraged to allow development by external partners - enabling adopters a straightforward integration into ICW solutions. The
eHealth: Connecting Health Care and Public Health.
Stud Health Technol Inform. 2008; 134: 169-76
Balas EA, Krishna S, Tessema TA
Reducing risks and improving benefits to the patients are requirements health professionals are faced with in their daily work. Furthermore, cuts in health funds and the competition for budgets require to enhancing efficacy and efficiency of health services. For meeting both challenges, adequate information and knowledge is needed, which can be gathered from documentation systems such as Electronic Health Records or Personal Health Records (PHRs), but also by performing dedicated clinical studies such as randomized controlled trials (RCTs) or
eHealth in Europe: from Vision to Reality.
Stud Health Technol Inform. 2008; 134: 163-8
Iakovidis I, Purcarea O
It is now 20 years that the European Union supports research and development of information and communication technologies based tools for healthcare (eHealth). From 1989 till today, funding has continually been increased, initiating new research, complementing Member State initiatives, strengthening European industrial competitiveness, and tackling new health and social problems related to the free movement of people in the EU. By now, many of the earlier visions and dreams have been realised or are close to wider implementation. Accordingly, the
eHealth for service delivery - special considerations for resource-challenged health systems.
Stud Health Technol Inform. 2008; 134: 97-106
Kwankam SY
Open Access
[Open-access endoscopy units.]
Med Clin (Barc). 2008 Apr 26; 130(15): 597-8
Sánchez Del Río García A, Alarcón Fernández O
An open challenge. Open access and the challenges for scientific publishing.
EMBO Rep. 2008 May; 9(5): 404-8
Bosch X
Diffusion of treatment research: does open access matter?
J Clin Psychol. 2008 Apr 18;
Hardisty DJ, Haaga DA
Advocates of the Open Access movement claim that removing access barriers will substantially increase the diffusion of academic research. If successful, this movement could play a role in efforts to increase utilization of psychotherapy research by mental health practitioners. In a pair of studies, mental health professionals were given either no citation, a normal citation, a linked citation, or a free access citation and were asked to find and read the cited article. After 1 week, participants read a vignette on the same topic as the article and gave recommendations
Exploring the assumptions underlying genetic variation in host nematode resistance (Open Access publication).
Genet Sel Evol. 2008 May-Jun; 40(3): 241-64
Doeschl-Wilson AB, Vagenas D, Kyriazakis I, Bishop SC
The wide range of genetic parameter estimates for production traits and nematode resistance in sheep obtained from field studies gives rise to much speculation. Using a mathematical model describing host - parasite interactions in a genetically heterogeneous lamb population, we investigated the consequence of: (i) genetic relationships between underlying growth and immunological traits on estimated genetic parameters for performance and nematode resistance, and (ii) alterations in resource allocation on these parameter
Benefits and dangers of university-sponsored open-access systems.
AJNR Am J Neuroradiol. 2008 Apr; 29(4): 617-8
Castillo M
A new paradigm for increasing use of open-access screening colonoscopy.
Clin Gastroenterol Hepatol. 2008 Apr; 6(4): 377-8
Holt CL, Schroy PC
Access evolved? Versatile open access policies are evolving together with scholarly information, but copyright issues remain unsettled.
EMBO Rep. 2008 Apr; 9(4): 317-21
Rinaldi A
Open access: taking full advantage of the content.
PLoS Comput Biol. 2008 Mar; 4(3): e1000037
Bourne PE, Fink JL, Gerstein M
Opening the lid on open access.
BMJ. 2008 Mar 29; 336(7646): 688-9
Mayor S
Creating open access to exercise for low-income patients through a community collaboration for quality improvement: if you build it, they will come.
J Ambul Care Manage. 2008 Apr-Jun; 31(2): 142-50
Candib LM, Silva M, Cashman SB, Ellstrom D, Mallett K
Community health centers face the need for safe, accessible, and affordable exercise for low-income patients to implement self-management strategies. This study reports on one federally qualified health center's experience developing a partnership with a local YWCA to offer open access to patients for physical activity. Over a 24-month period, 1060 adult patients made at least 1 visit to the YWCA, logging a total of 14,276 visits. Among the exercisers, 112 had diabetes and made 3225 visits. Frequent users (> or =24