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Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Jan 24, 2020
Open Peer Review Period: Jan 24, 2020 - Mar 20, 2020
Date Accepted: Jul 27, 2020
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Fueling Clinical and Translational Research in Appalachia: Informatics Platform Approach

Cecchetti AA, Bhardwaj N, Murughiyan U, Kothakapu G, Sundaram U

Fueling Clinical and Translational Research in Appalachia: Informatics Platform Approach

JMIR Med Inform 2020;8(10):e17962

DOI: 10.2196/17962

PMID: 33052114

PMCID: 7593861

Appalachian Informatics Platform – A Multicentric Data Warehouse with Embedded Data Analytics and Interactive Visualization for Clinical and Translational Research

  • Alfred A Cecchetti; 
  • Niharika Bhardwaj; 
  • Usha Murughiyan; 
  • Gouthami Kothakapu; 
  • Uma Sundaram

ABSTRACT

Background:

The Appalachian population is distinct, not just culturally and geographically, but also in its health care needs, facing the most health care disparities in the United States. Thus, to meet these unique demands, bringing in modern technologies to Appalachian medical centers and utilizing these technologies to develop solutions becomes critical. This requires the foundation of a centralized data warehouse with an arsenal of analytics and data science tools to transform healthcare data into actionable clinical interventions. It’s an especially challenging task given the fragmented state of medical data within Appalachia and the need for integration of other types of data such as environmental, social, economic, etc. with medical data.

Objective:

This paper presents the initial experience of developing an integrated platform at a mid-level Appalachian academic medical center along with its initial uses.

Methods:

The Appalachian Informatics Platform was developed by the Appalachian Clinical and Translational Science Institute’s Division of Clinical Informatics and consists of four major components: a centralized clinical data warehouse, modeling (statistical and machine learning), visualization, and model evaluation.

Results:

The Appalachian informatics platform is functional and has supported several research efforts since its implementation.

Conclusions:

The platform provides an inexpensive yet seamless way to translate clinical and translational research ideas into clinical applications for regions like Appalachia that have limited resources and a largely rural population.


 Citation

Please cite as:

Cecchetti AA, Bhardwaj N, Murughiyan U, Kothakapu G, Sundaram U

Fueling Clinical and Translational Research in Appalachia: Informatics Platform Approach

JMIR Med Inform 2020;8(10):e17962

DOI: 10.2196/17962

PMID: 33052114

PMCID: 7593861

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