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Currently submitted to: Journal of Medical Internet Research

Date Submitted: Jan 11, 2020
Open Peer Review Period: Jan 11, 2020 - Mar 7, 2020
(currently open for review)

Artificial Intelligence and Health Technology Assessment: Anticipating a New Level of Complexity

  • Hassane Alami; 
  • Pascale Lehoux; 
  • Yannick Auclair; 
  • Michèle de Guise; 
  • Marie-Pierre Gagnon; 
  • James Shaw; 
  • Denis Roy; 
  • Richard Fleet; 
  • Mohamed Ali Ag Ahmed; 
  • Jean-Paul Fortin; 


Artificial Intelligence is seen as a strategic lever to improve access, quality and efficiency of care and services, and to build learning and value-based health systems. Many studies examined the technical performance of AI within an experimental context. These studies provide limited insights into the issues that its use in a real-world context of care and services (RWCCS) raises. To help decision-makers address these issues in a systemic and holistic way, this article relies on the "Health Technology Assessment (HTA) core model" to contrast the expectations of the health sector towards the use of AI with the risks that should be mitigated for its responsible deployment. The analysis adopts the perspective of payors because of their central role in regulating, financing and reimbursing novel technologies. This article suggests that AI-based systems should be seen as a health system transformation lever, rather than a discrete set of technological devices. Their use could bring significant changes and impacts at several levels: technological, clinical, human and cognitive (patient and clinician), professional and organizational, economic, legal and ethical. The assessment of the "AI value proposition" should thus go beyond "technical performance" and "price" logics by performing a holistic analysis of value in a RWCCS. In order to guide AI developments, generate knowledge and draw lessons that can be translated into action, the right political, regulatory, organizational, clinical and technological conditions for innovation should be created as a first step.


Please cite as:

Alami H, Lehoux P, Auclair Y, de Guise M, Gagnon M, Shaw J, Roy D, Fleet R, Ag Ahmed MA, Fortin J

Artificial Intelligence and Health Technology Assessment: Anticipating a New Level of Complexity

JMIR Preprints. 11/01/2020:17707

DOI: 10.2196/preprints.17707


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